Compile Data Set for Download or QSAR
Report error Found 592 Enz. Inhib. hit(s) with all data for entry = 12066
TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675686BDBM675686(3-((2S)-3-(8-(4-bromo-3-chlorophenylsulfonyl)-1-ox...)
Affinity DataIC50: 4.36nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675561BDBM675561(3-((S)-2-hydroxy-3-((R)-8-(naphthalen-2-ylsulfonyl...)
Affinity DataIC50: 4.41nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675560BDBM675560(3-((S)-2-hydroxy-3-((S)-8-(naphthalen-2-ylsulfonyl...)
Affinity DataIC50: 4.53nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675690BDBM675690(3-((2S)-3-(8-(4-bromo-3-methylphenylsulfonyl)-1-ox...)
Affinity DataIC50: 4.78nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676041BDBM676041(US11987588, Compound 510 | 3-((S)-3-((R)-8-(3-chlo...)
Affinity DataIC50: 4.89nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675682BDBM675682(3-((2S)-3-(8-(4-chloro-3-methylphenylsulfonyl)-1-o...)
Affinity DataIC50: 5.38nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675532BDBM675532(3-((2S)-2-hydroxy-3-(8-(naphthalen-2-ylsulfonyl)-1...)
Affinity DataIC50: 5.40nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676044BDBM676044(US11987588, Compound 513 | 3-((S)-3-((R)-8-(3-chlo...)
Affinity DataIC50: 6.36nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676043BDBM676043(US11987588, Compound 512 | 3-((S)-2-hydroxy-3-((R)...)
Affinity DataIC50: 6.62nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675572BDBM675572(3-((2S)-3-(8-(chroman-6-ylsulfonyl)-1-oxa-8-azaspi...)
Affinity DataIC50: 6.82nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676040BDBM676040(US11987588, Compound 509 | 3-((S)-2-hydroxy-3-((R)...)
Affinity DataIC50: 6.95nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676057BDBM676057(US11987588, Compound 526 | 3-((S)-2-hydroxy-3-((R)...)
Affinity DataIC50: 6.97nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675610BDBM675610(3-((2S)-3-(8-(4'-(aminomethyl)biphenyl-3-ylsulfony...)
Affinity DataIC50: 7.15nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675826BDBM675826(3-((S)-3-((S)-8-(3-(1H-pyrazol-3-yl)phenylsulfonyl...)
Affinity DataIC50: 7.22nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675716BDBM675716(3-((2S)-3-(8-(7-chlorobenzo[c][1,2,5]oxadiazol-4-y...)
Affinity DataIC50: 7.25nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675746BDBM675746(3-((S)-2-hydroxy-3-((R)-8-(3-(1-methyl-1H-pyrazol-...)
Affinity DataIC50: 7.41nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675547BDBM675547(3-((2S)-2-hydroxy-3-(8-(5,6,7,8-tetrahydronaphthal...)
Affinity DataIC50: 7.47nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675802BDBM675802(3-((S)-3-((R)-8-(4-bromo-3-methylphenylsulfonyl)-1...)
Affinity DataIC50: 7.53nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675718BDBM675718(3-((2S)-2-hydroxy-3-(8-(5-phenylthiophen-2-ylsulfo...)
Affinity DataIC50: 7.72nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676048BDBM676048(US11987588, Compound 517 | 3-((S)-3-((R)-8-(3-chlo...)
Affinity DataIC50: 7.74nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675710BDBM675710(3-((2S)-3-(8-(3-fluoro-5-methylphenylsulfonyl)-1-o...)
Affinity DataIC50: 8.15nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675661BDBM675661(3-((2S)-2-hydroxy-3-(8-(6-phenoxypyridin-3-ylsulfo...)
Affinity DataIC50: 8.32nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676036BDBM676036(US11987588, Compound 505 | 3-((S)-3-((R)-8-(1H-pyr...)
Affinity DataIC50: 8.46nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675720BDBM675720(3-((2S)-2-hydroxy-3-(8-(4-methyl-3,4-dihydro-2H-be...)
Affinity DataIC50: 8.51nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675729BDBM675729(3-((2S)-3-(8-(3-cyano-4-methylphenylsulfonyl)-1-ox...)
Affinity DataIC50: 8.65nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675738BDBM675738(3-((2S)-3-(8-(3-chloro-4-methoxyphenylsulfonyl)-1-...)
Affinity DataIC50: 8.79nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675822BDBM675822(3'-((S)-3-((S)-2-hydroxy-3-(3-(N-methylsulfamoyl)p...)
Affinity DataIC50: 8.84nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675864BDBM675864(US11987588, Compound 333 | 3-((2S)-3-(8-(4-ethyl-3...)
Affinity DataIC50: 9.02nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676058BDBM676058(US11987588, Compound 527 | 3-((S)-3-((R)-8-(3-chlo...)
Affinity DataIC50: 9.03nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675615BDBM675615(3-((2S)-3-(8-(3-(1H-pyrazol-3-yl)phenylsulfonyl)-1...)
Affinity DataIC50: 9.09nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675617BDBM675617(3-((2S)-2-hydroxy-3-(8-(4'-(methylsulfonamido)biph...)
Affinity DataIC50: 9.36nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675798BDBM675798(3-((S)-2-hydroxy-3-((R)-8-(4-methoxy-3-methylpheny...)
Affinity DataIC50: 9.43nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675752BDBM675752(3-((2S)-2-hydroxy-3-(8-(1-methyl-1H-indol-5-ylsulf...)
Affinity DataIC50: 9.58nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675632BDBM675632(N-ethyl-3-((2S)-2-hydroxy-3-(8-(naphthalen-2-ylsul...)
Affinity DataIC50: 9.62nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675737BDBM675737(3-((2S)-3-(8-(4-chloro-3-methoxyphenylsulfonyl)-1-...)
Affinity DataIC50: 9.62nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675950BDBM675950(US11987588, Compound 419 | 3-((S)-3-((S)-8-(4'-(am...)
Affinity DataIC50: 9.69nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675616BDBM675616(3'-(3-((S)-2-hydroxy-3-(3-(N-methylsulfamoyl)pheno...)
Affinity DataIC50: 9.73nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675619BDBM675619(3-((2S)-2-hydroxy-3-(8-(3-(pyridin-3-yl)phenylsulf...)
Affinity DataIC50: 9.82nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675942BDBM675942(3-((2S)-3-(8-(4'-(aminomethyl)-4-(trifluoromethoxy...)
Affinity DataIC50: 9.84nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675550BDBM675550(3-((2S)-3-(8-(3,4-dimethylphenylsulfonyl)-1-oxa-8-...)
Affinity DataIC50: 10nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675670BDBM675670(3-((2S)-3-(8-(3-chloro-2-fluorophenylsulfonyl)-1-o...)
Affinity DataIC50: 10.2nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675951BDBM675951(US11987588, Compound 420 | 3-((S)-3-((R)-8-(4'-(am...)
Affinity DataIC50: 10.2nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676059BDBM676059(US11987588, Compound 528 | 3-((S)-2-hydroxy-3-((R)...)
Affinity DataIC50: 10.2nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675645BDBM675645(3-((2S)-3-(8-(4'-(cyanomethoxy)biphenyl-3-ylsulfon...)
Affinity DataIC50: 10.3nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675634BDBM675634(3-((2S)-3-(8-(3-(6-aminopyridin-3-yl)phenylsulfony...)
Affinity DataIC50: 10.5nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 676024BDBM676024(US11987588, Compound 493 | 3-((S)-3-((R)-8-(3-cyan...)
Affinity DataIC50: 10.6nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675812BDBM675812(3-((S)-2-hydroxy-3-((R)-8-(5-methyl-1-phenyl-1H-py...)
Affinity DataIC50: 10.7nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675733BDBM675733(3-((2S)-3-(8-(2-chloro-5-fluorophenylsulfonyl)-1-o...)
Affinity DataIC50: 10.8nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675663BDBM675663(3-((2S)-2-hydroxy-3-(8-(5-methyl-1-phenyl-1H-pyraz...)
Affinity DataIC50: 10.8nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

TargetBeta-3 adrenergic receptor(Human)
Arena Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 675638BDBM675638(3-((2S)-2-hydroxy-3-(8-(3-(2-methylpyridin-4-yl)ph...)
Affinity DataIC50: 10.9nMAssay Description:HTRF cAMP assays were performed according to manufacturer's instructions (Cisbio, cAMP Dynamic 2 Assay Kit; #62AM4PEJ). CHO-K1 cells stably expre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2024
Entry Details
US Patent

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