Compile Data Set for Download or QSAR
Report error Found 400 Enz. Inhib. hit(s) with all data for entry = 12104
TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50009049BDBM50009049(CHEMBL12047 | (+/-)(1-Methyl-2-phenyl-ethyl)-(4-ph...)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679152BDBM679152(US11999676, Compound 14)
Affinity DataKi:  3nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679358BDBM679358(US11999676, Compound 222)
Affinity DataKi:  4.97nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679360BDBM679360(US11999676, Compound 225)
Affinity DataKi:  4.99nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679359BDBM679359(US11999676, Compound 223)
Affinity DataKi:  5.01nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679206BDBM679206(US11999676, Compound 68 | US11999676, Compound 69)
Affinity DataKi:  5.53nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679206BDBM679206(US11999676, Compound 68 | US11999676, Compound 69)
Affinity DataKi:  5.53nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679150BDBM679150(US11999676, Compound 12)
Affinity DataKi:  6nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50041279BDBM50041279(((R)-1-Methyl-2-phenyl-ethyl)-(3-phenyl-propyl)-am...)
Affinity DataKi:  6nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679307BDBM679307(US11999676, Compound 170 | US11999676, Compound 17...)
Affinity DataKi:  6.74nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679307BDBM679307(US11999676, Compound 170 | US11999676, Compound 17...)
Affinity DataKi:  6.74nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679349BDBM679349(US11999676, Compound 212 | US11999676, Compound 21...)
Affinity DataKi:  6.86nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679349BDBM679349(US11999676, Compound 212 | US11999676, Compound 21...)
Affinity DataKi:  6.86nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 85392BDBM85392(CAS_131443 | NSC_131443 | PPAP, (-) | US11999676, ...)
Affinity DataKi:  7nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679254BDBM679254(US11999676, Compound 117 | US11999676, Compound 12...)
Affinity DataKi:  7.08nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679254BDBM679254(US11999676, Compound 117 | US11999676, Compound 12...)
Affinity DataKi:  7.08nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679333BDBM679333(US11999676, Compound 196 | US11999676, Compound 19...)
Affinity DataKi:  7.12nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679333BDBM679333(US11999676, Compound 196 | US11999676, Compound 19...)
Affinity DataKi:  7.12nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 50006975BDBM50006975(CHEMBL19802 | [2-(4-Bromo-phenyl)-1-methyl-ethyl]-...)
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679181BDBM679181(US11999676, Compound 43)
Affinity DataKi:  8nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679327BDBM679327(US11999676, Compound 190 | US11999676, Compound 19...)
Affinity DataKi:  8.28nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679327BDBM679327(US11999676, Compound 190 | US11999676, Compound 19...)
Affinity DataKi:  8.28nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679262BDBM679262(US11999676, Compound 125)
Affinity DataKi:  8.58nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679147BDBM679147(US11999676, Compound 9)
Affinity DataKi:  8.70nMAssay Description:Synaptic vesicles were prepared from rat brain using a modification of a previously described procedure (Teng et al., 1998). Briefly, fresh whole bra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679212BDBM679212(US11999676, Compound 74)
Affinity DataKi:  8.82nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679156BDBM679156(US11999676, Compound 18)
Affinity DataKi:  9nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679321BDBM679321(US11999676, Compound 184 | US11999676, Compound 18...)
Affinity DataKi:  9.06nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679321BDBM679321(US11999676, Compound 184 | US11999676, Compound 18...)
Affinity DataKi:  9.06nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679254BDBM679254(US11999676, Compound 117 | US11999676, Compound 12...)
Affinity DataKi:  9.85nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679254BDBM679254(US11999676, Compound 117 | US11999676, Compound 12...)
Affinity DataKi:  9.85nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679172BDBM679172(US11999676, Compound 34)
Affinity DataKi:  10nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679177BDBM679177(US11999676, Compound 39 | US11999676, Compound 126...)
Affinity DataKi:  10nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679167BDBM679167(US11999676, Compound 29)
Affinity DataKi:  11nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679329BDBM679329(US11999676, Compound 192 | US11999676, Compound 19...)
Affinity DataKi:  11.9nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679329BDBM679329(US11999676, Compound 192 | US11999676, Compound 19...)
Affinity DataKi:  11.9nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679154BDBM679154(US11999676, Compound 16)
Affinity DataKi:  12nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679225BDBM679225(US11999676, Compound 87 | US11999676, Compound 90 ...)
Affinity DataKi:  12.7nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679225BDBM679225(US11999676, Compound 87 | US11999676, Compound 90 ...)
Affinity DataKi:  12.7nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679225BDBM679225(US11999676, Compound 87 | US11999676, Compound 90 ...)
Affinity DataKi:  12.7nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679225BDBM679225(US11999676, Compound 87 | US11999676, Compound 90 ...)
Affinity DataKi:  12.7nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679158BDBM679158(US11999676, Compound 20)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679180BDBM679180(US11999676, Compound 42 | US11999676, Compound 115...)
Affinity DataKi:  13nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679197BDBM679197(US11999676, Compound 59)
Affinity DataKi:  13.1nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679258BDBM679258(US11999676, Compound 121 | US11999676, Compound 12...)
Affinity DataKi:  13.4nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679258BDBM679258(US11999676, Compound 121 | US11999676, Compound 12...)
Affinity DataKi:  13.4nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679155BDBM679155(US11999676, Compound 17)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679146BDBM679146(US11999676, Compound 8)
Affinity DataKi:  14nMAssay Description:Inhibition of [3H]DA uptake was conducted using isolated synaptic vesicle preparations (Teng et al., 1997). Briefly, rat striata were homogenized wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679355BDBM679355(US11999676, Compound 218 | US11999676, Compound 21...)
Affinity DataKi:  14.2nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679355BDBM679355(US11999676, Compound 218 | US11999676, Compound 21...)
Affinity DataKi:  14.2nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

TargetSodium-dependent dopamine transporter(Rat)
University Of Kentucky Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 679297BDBM679297(US11999676, Compound 160 | US11999676, Compound 16...)
Affinity DataKi:  14.3nMAssay Description:[3H]DA and [3H]5-HT uptake into striatal synaptosomes was determined to evaluate compound inhibition of the dopamine transporter (DAT) and the seroto...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
US Patent

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