Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 12240
LigandChemical structure of BindingDB Monomer ID 484440BDBM484440(US10934285, Example 24 | US12053470, Compound 47)
Affinity DataIC50: 1nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408072BDBM408072(US10336774, Example 57 | US12053470, Compound 13)
Affinity DataIC50: 3nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408073BDBM408073(US10336774, Example 58 | US12053470, Compound 14)
Affinity DataIC50: 4nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484467BDBM484467(US10934285, Example 53 | US12053470, Compound 46)
Affinity DataIC50: 4nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689290BDBM689290(US12053470, Compound 18 | (2R,4R)-4-amino-8-(5-((2...)
Affinity DataIC50: 4.5nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689281BDBM689281(US12053470, Compound 12 | (1R,3R)-8-(6-amino-5-((2...)
Affinity DataIC50: 5nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484429BDBM484429(US10934285, Example 13 | US12053470, Compound 52)
Affinity DataIC50: 5nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689316BDBM689316(US12053470, Compound 44 | N-(3-((3-amino-5-(4-amin...)
Affinity DataIC50: 6nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689296BDBM689296(US12053470, Compound 24 | (S)-8-(5-((2-amino-3- ch...)
Affinity DataIC50: 6nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689292BDBM689292(US12053470, Compound 20 | (1R)-8-(5-((2-amino-3- c...)
Affinity DataIC50: 6nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689291BDBM689291(US12053470, Compound 19 | (1R,3R)-8-(5-((2-amino-3...)
Affinity DataIC50: 6nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484430BDBM484430(US10934285, Example 14 | US12053470, Compound 51)
Affinity DataIC50: 6nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484423BDBM484423(US10934285, Example 7 | US12053470, Compound 48)
Affinity DataIC50: 6nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 408067BDBM408067(US10336774, Example 52 | US12053470, Compound 11)
Affinity DataIC50: 7nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50553790BDBM50553790(CHEMBL4763213 | US12053470, Compound 23)
Affinity DataIC50: 7nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484418BDBM484418(US10934285, Example 2 | US12053470, Compound 50)
Affinity DataIC50: 7nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484468BDBM484468(US10934285, Example 54 | US12053470, Compound 54)
Affinity DataIC50: 7.30nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689294BDBM689294(US12053470, Compound 22 | (3S,4S)-8-(5-((2-amino-3...)
Affinity DataIC50: 8nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689313BDBM689313(US12053470, Compound 41 | (R)-3-(6-amino-2- methyl...)
Affinity DataIC50: 9nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689284BDBM689284(US12053470, Compound 15 | (1R)-8-(6-amino-5-((2-am...)
Affinity DataIC50: 9nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689289BDBM689289(US12053470, Compound 17 | (3S,4S)-8-(6-amino-5-((2...)
Affinity DataIC50: 9nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50553783BDBM50553783(Ptpn11 inhibitor tno155 | Shp2 inhibitor tno155 | ...)
Affinity DataIC50: 10nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50553787BDBM50553787(CHEMBL4755819 | US12053470, Compound 5)
Affinity DataIC50: 11nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 396027BDBM396027(US10308660, Example 129 | US12053470, Compound 29)
Affinity DataIC50: 14nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50553789BDBM50553789(CHEMBL4747789 | US12053470, Compound 6)
Affinity DataIC50: 14nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689293BDBM689293(US12053470, Compound 21 | (3S,4S)-8-(5-((6-amino-2...)
Affinity DataIC50: 14nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 395966BDBM395966(US10308660, Example 42 | US12053470, Compound 33)
Affinity DataIC50: 14nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689312BDBM689312(US12053470, Compound 40 | 3-(6-amino-2-methylpyrid...)
Affinity DataIC50: 16nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 395944BDBM395944(US10308660, Example 20 | US12053470, Compound 30)
Affinity DataIC50: 17nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689300BDBM689300(US12053470, Compound 28 | 6-amino-2-((1R,3R)-1-ami...)
Affinity DataIC50: 18nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689325BDBM689325(US12053470, Compound 53 | (S)-N-(3-((3-amino-5-(4-...)
Affinity DataIC50: 18nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 395955BDBM395955(US10308660, Example 31 | US12053470, Compound 32)
Affinity DataIC50: 20nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689303BDBM689303(US12053470, Compound 31 | 6-amino-2-((3S,4S)-4-ami...)
Affinity DataIC50: 21nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484441BDBM484441(N-(3-((3-Amino-5-((3S,4S)-4-amino-3-methyl-2-oxa-8...)
Affinity DataIC50: 23nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689279BDBM689279(US12053470, Compound 10 | (S)-8-(6-amino-5-((2- (t...)
Affinity DataIC50: 25nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 396038BDBM396038(US10308660, Example 140 | US12053470, Compound 36)
Affinity DataIC50: 25nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689315BDBM689315(US12053470, Compound 43 | 2-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 26nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689309BDBM689309(US12053470, Compound 37 | (R)-6-(1-amino-8- azaspi...)
Affinity DataIC50: 26nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 392315BDBM392315(6-(4-(aminomethyl)-4-methylpiperidin-1-yl)-3-((2-(...)
Affinity DataIC50: 29nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 395936BDBM395936(US10308660, Example 12 | US12053470, Compound 27)
Affinity DataIC50: 33nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689314BDBM689314(US12053470, Compound 42 | 6-((3S,4S)-4-amino-3-met...)
Affinity DataIC50: 36nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689276BDBM689276(US12053470, Compound 7 | (3S,4S)-8-(6-amino-5-(2,3...)
Affinity DataIC50: 39nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 484442BDBM484442(US10934285, Example 28 | US12053470, Compound 49)
Affinity DataIC50: 42nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50530239BDBM50530239(CHEMBL4442335 | US12053470, Compound 26)
Affinity DataIC50: 48nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 395844BDBM395844(6-amino-2-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspi...)
Affinity DataIC50: 53nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 689310BDBM689310(US12053470, Compound 38 | 2-(4-(aminomethyl)-4- me...)
Affinity DataIC50: 62nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 38042BDBM38042(US10093646, Example 12 | US10774065, Example 12 | ...)
Affinity DataIC50: 65nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 492388BDBM492388(US10975080, Example 85 | US12053470, Compound 39)
Affinity DataIC50: 67nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 38019BDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 71nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50546225BDBM50546225(CHEMBL4752507 | US12053470, Compound 9)
Affinity DataIC50: 73nMAssay Description:More specifically, the phosphatase reactions were performed at room temperature in 384-well black polystyrene plate, flat bottom, low flange, non-bin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2024
Entry Details
US Patent

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