Compile Data Set for Download or QSAR
Report error Found 746 Enz. Inhib. hit(s) with all data for entry = 12260
TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691028BDBM691028(US12065436, Compound 417 | (R)-N-(5-(5-ethylisoxaz...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691231BDBM691231(US12065436, Compound 620 | (R)-3-chloro-N-(5-(5-et...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691025BDBM691025((R)-N-(5-(5-ethylisoxazol-3-yl)-2,3- dihydro-1H-in...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691035BDBM691035(US12065436, Compound 424 | (S)-N-(6-(5-ethylisoxaz...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691175BDBM691175(US12065436, Compound 564 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 600nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690915BDBM690915(methyl (R)-(5-(5-ethyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691268BDBM691268(US12065436, Compound 657 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691264BDBM691264(US12065436, Compound 653 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691066BDBM691066(US12065436, Compound 455 | (S)-N-(6-(5-ethyl-1,2,4...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691020BDBM691020((R)-N-(5-(5-cyclobutyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690951BDBM690951((S)-N-(6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691064BDBM691064(US12065436, Compound 453 | (S)-N-(6-(5-(difluorome...)
Affinity DataIC50: 700nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690851BDBM690851((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690997BDBM690997((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690852BDBM690852((R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690703BDBM690703((R)-N-(5-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690864BDBM690864((R)-N-(5-(5-ethylisoxazol-3-yl)-2,3- dihydro-1H-in...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690956BDBM690956(methyl (R)-(5-(5-ethylisoxazol-3-yl)- 2,3-dihydro-...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691244BDBM691244(US12065436, Compound 633 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690839BDBM690839((S)-N-(6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691177BDBM691177(US12065436, Compound 566 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691032BDBM691032(US12065436, Compound 421 | (S)-N-(6-(5-ethylisoxaz...)
Affinity DataIC50: 800nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691042BDBM691042(US12065436, Compound 431 | (R)-N-(5-(5-ethylisoxaz...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691269BDBM691269(US12065436, Compound 658 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691044BDBM691044(US12065436, Compound 433 | (S)-N-(6-(5-ethylisoxaz...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690752BDBM690752((R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690944BDBM690944(2,2-difluoroethyl (R)-(5-(5-ethyl- 1,2,4-oxadiazol...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690794BDBM690794((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690726BDBM690726((R)-N-(5-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691059BDBM691059(US12065436, Compound 448 | (R)-N-(5-(5-(difluorome...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690802BDBM690802((S)-N-(6-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690933BDBM690933(isobutyl (R)-(5-(5-ethyl-1,2,4- oxadiazol-3-yl)-2,...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691220BDBM691220(US12065436, Compound 609 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690735BDBM690735((S)-N-(6-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691214BDBM691214((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690704BDBM690704((R)-N-(5-(5-(difluoromethyl)-1,2,4- oxadiazol-3-yl...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690960BDBM690960(methyl (S)-(6-(5-ethyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691258BDBM691258(US12065436, Compound 647 | (R)-2-chloro-N-(5-(5-et...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690934BDBM690934(cyclopropylmethyl (R)-(5-(5-ethyl- 1,2,4-oxadiazol...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691288BDBM691288(US12065436, Compound 677 | (R)-N-(5-(5-(difluorome...)
Affinity DataIC50: 900nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690754BDBM690754((R)-N-(5-(5-cyclobutyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691010BDBM691010((R)-N-(5-(5-cyclobutyl-1,2,4- oxadiazol-3-yl)-2,3-...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691173BDBM691173(US12065436, Compound 562 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690849BDBM690849((S)-N-(6-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691178BDBM691178(US12065436, Compound 567 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691239BDBM691239(US12065436, Compound 628 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691206BDBM691206(US12065436, Compound 595 | (R)-N-(5-(5-ethyl-1,2,4...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690868BDBM690868((R)-N-(5-(3-ethyl-1,2,4-oxadiazol-5- yl)-2,3-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 691214BDBM691214((R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3- yl)-2,3-dihyd...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetMyosin-1(Bovine)
Cytokinetics

US Patent
LigandChemical structure of BindingDB Monomer ID 690833BDBM690833((S)-N-(6-(5-cyclopropyl-1,2,4- oxadiazol-3-yl)-2,3...)
Affinity DataIC50: 1.00E+3nMAssay Description:To evaluate the effect of compounds on the ATPase activity of full-length cardiac myosin in the context of the native sarcomere, skinned myofibril as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

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