Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 12323
TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695523BDBM695523(US12084416, Example 21)
Affinity DataIC50: 2.40nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695530BDBM695530(US12084416, Example 91)
Affinity DataIC50: 2.90nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695533BDBM695533(US12084416, Example 111)
Affinity DataIC50: 4.30nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695535BDBM695535(US12084416, Example 127)
Affinity DataIC50: 5.60nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695536BDBM695536(US12084416, Example 129)
Affinity DataIC50: 5.90nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695514BDBM695514(US12084416, Example 4)
Affinity DataIC50: 7.40nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695526BDBM695526(US12084416, Example 63)
Affinity DataIC50: 8nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695528BDBM695528(US12084416, Example 84)
Affinity DataIC50: 8.5nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695539BDBM695539(US12084416, Example 144)
Affinity DataIC50: 8.60nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695525BDBM695525(US12084416, Example 56)
Affinity DataIC50: 8.80nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695521BDBM695521(US12084416, Example 13)
Affinity DataIC50: 9nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695519BDBM695519(US12084416, Example 8)
Affinity DataIC50: 10.7nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695541BDBM695541(US12084416, Example 149)
Affinity DataIC50: 11nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695540BDBM695540(US12084416, Example 147)
Affinity DataIC50: 11nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695524BDBM695524(US12084416, Example 23)
Affinity DataIC50: 14nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695537BDBM695537(US12084416, Example 131)
Affinity DataIC50: 16nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695529BDBM695529(US12084416, Example 90)
Affinity DataIC50: 16nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695534BDBM695534(US12084416, Example 125)
Affinity DataIC50: 16.4nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695522BDBM695522(US12084416, Example 14)
Affinity DataIC50: 17nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695538BDBM695538(US12084416, Example 139)
Affinity DataIC50: 21nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695542BDBM695542(US12084416, Example 153)
Affinity DataIC50: 32nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695532BDBM695532(US12084416, Example 105)
Affinity DataIC50: 61nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695520BDBM695520(US12084416, Example 10)
Affinity DataIC50: 64nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695531BDBM695531(US12084416, Example 100)
Affinity DataIC50: 70nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent

TargetInterleukin-1 beta(Human)
Zydus Lifesciences

US Patent
LigandChemical structure of BindingDB Monomer ID 695527BDBM695527(US12084416, Example 71)
Affinity DataIC50: 87nMAssay Description:THP1 monocytes were differentiated with PMA (100 ng/mL) and incubated at 37 deg C. for 20 hrs in presence of 5% CO2. 2×105 differentiated cells were ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
1/6/2025
Entry Details
US Patent