Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 12481
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50569896(CHEMBL4865688 | US12145923, Compound (S)-C10)
Affinity DataIC50: 5.00E+4nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50248919((S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsu...)
Affinity DataIC50: 7.40E+4nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705346(US12145923, Compound (S)-C8)
Affinity DataIC50: 8.00E+4nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50569895(CHEMBL4862887 | US12145923, Compound C10)
Affinity DataIC50: 8.00E+4nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525176(CHEMBL4466435 | US12145923, Compound (S)-C9)
Affinity DataIC50: 1.20E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525166(CHEMBL4543264 | US12145923, Compound (S)-A4)
Affinity DataIC50: 1.30E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705341(US12145923, Compound (S)-B11)
Affinity DataIC50: 1.90E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50569876(CHEMBL4874067 | US12145923, Compound C9)
Affinity DataIC50: 2.10E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705338(US12145923, Compound A4)
Affinity DataIC50: 2.30E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525172(CHEMBL4443701 | US12145923, Compound (S)-C4)
Affinity DataIC50: 2.40E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525165(CHEMBL4527894 | US12145923, Compound (S)-C5)
Affinity DataIC50: 2.40E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705343(US12145923, Compound (S)-B12)
Affinity DataIC50: 2.50E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525174(CHEMBL4592339 | US12145923, Compound (S)-C6)
Affinity DataIC50: 2.50E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525175(CHEMBL4520636 | US12145923, Compound (S)-A1)
Affinity DataIC50: 2.70E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705336(US12145923, Compound B4)
Affinity DataIC50: 3.00E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525177(CHEMBL4532140 | US12145923, Compound (S)-C7)
Affinity DataIC50: 3.30E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525175(CHEMBL4520636 | US12145923, Compound (S)-A1)
Affinity DataIC50: 3.80E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705345(US12145923, Compound B8)
Affinity DataIC50: 5.70E+5nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50569922(CHEMBL4863942 | US12145923, Compound (S)-C17)
Affinity DataIC50: 1.10E+6nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705330(US12145923, Compound C1)
Affinity DataIC50: 1.50E+6nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM50525164(CHEMBL4536368 | US12145923, Compound (S)-A3)
Affinity DataIC50: 1.80E+6nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Shanghai Institute of Materia Medica

US Patent
LigandPNGBDBM705329(US12145923, Compound A2)
Affinity DataIC50: 2.99E+6nMAssay Description:The scintillation Proximity Assay (SPA) method was used to determine the inhibitory effect of compounds on the activity of PDE4D catalytic domain. Hu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
4/8/2025
Entry Details
US Patent