Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 12672
TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719056(US12221449, Compound I-2)
Affinity DataIC50: 1.35nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719057(US12221449, Compound I-2S)
Affinity DataIC50: 1.40nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622503(US20230312582, Example Compound Formula (I) | US12...)
Affinity DataIC50: 1.59nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622500(US20230312582, Example Control | US12221449, Contr...)
Affinity DataIC50: 2.60nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719054(US12221449, Compound I-1R)
Affinity DataIC50: 2.67nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719053(US12221449, Compound I-1)
Affinity DataIC50: 4.24nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetAutotaxin(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719055(US12221449, Compound I-1S)
Affinity DataIC50: 28.6nMAssay Description:The inhibitory activities of the compounds on the autotaxin enzyme were detected using the Autotaxin Inhibitor Screening Assay Kit (Cayman, 700580). ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622500(US20230312582, Example Control | US12221449, Contr...)
Affinity DataIC50: 6.69E+3nMAssay Description:Full-automatic electrophysiological patch clamp QPatch was used to detect the inhibitory effect of compounds on hERG. Cells used in this test were CH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719057(US12221449, Compound I-2S)
Affinity DataIC50: 8.78E+3nMAssay Description:Full-automatic electrophysiological patch clamp QPatch was used to detect the inhibitory effect of compounds on hERG. Cells used in this test were CH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM622503(US20230312582, Example Compound Formula (I) | US12...)
Affinity DataIC50: 9.48E+3nMAssay Description:Full-automatic electrophysiological patch clamp QPatch was used to detect the inhibitory effect of compounds on hERG. Cells used in this test were CH...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719054(US12221449, Compound I-1R)
Affinity DataIC50: 2.20E+4nMAssay Description:Full-automatic electrophysiological patch clamp QPatch was used to detect the inhibitory effect of compounds on hERG. Cells used in this test were CH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Wuhan Humanwell Innovative Drug Research And Development Center

US Patent
LigandPNGBDBM719053(US12221449, Compound I-1)
Affinity DataIC50: 2.23E+4nMAssay Description:Full-automatic electrophysiological patch clamp QPatch was used to detect the inhibitory effect of compounds on hERG. Cells used in this test were CH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/15/2025
Entry Details
US Patent