Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 12746
TargetCytochrome P450 2C19(Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM724725((S)—N-(3-cyano-4-fluorophenyl)-2,4-dimethyl-5-(2-o...)
Affinity DataIC50: 2.00E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of human liver microsomes (protein concentration: 0.2 mg/mL, Corning), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetCytochrome P450 1A2(Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM724725((S)—N-(3-cyano-4-fluorophenyl)-2,4-dimethyl-5-(2-o...)
Affinity DataIC50: 4.90E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of human liver microsomes (protein concentration: 0.2 mg/mL, Corning), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetCytochrome P450 2D6(Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM724725((S)—N-(3-cyano-4-fluorophenyl)-2,4-dimethyl-5-(2-o...)
Affinity DataIC50: 5.40E+4nMAssay Description:500 μL of a final incubation system contains 50 μL of human liver microsomes (protein concentration: 0.2 mg/mL, Corning), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM724725((S)—N-(3-cyano-4-fluorophenyl)-2,4-dimethyl-5-(2-o...)
Affinity DataIC50: 2.00E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of human liver microsomes (protein concentration: 0.2 mg/mL, Corning), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetCytochrome P450 2B6(Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM724725((S)—N-(3-cyano-4-fluorophenyl)-2,4-dimethyl-5-(2-o...)
Affinity DataIC50: 2.00E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of human liver microsomes (protein concentration: 0.2 mg/mL, Corning), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent

TargetCytochrome P450 3A4(Human)
Chia Tai Tianqing Pharmaceutical Group Co.

US Patent
LigandPNGBDBM724725((S)—N-(3-cyano-4-fluorophenyl)-2,4-dimethyl-5-(2-o...)
Affinity DataIC50: 2.00E+5nMAssay Description:500 μL of a final incubation system contains 50 μL of human liver microsomes (protein concentration: 0.2 mg/mL, Corning), 1 μL of mixed CYP450 specif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/3/2025
Entry Details
US Patent