Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 12776
LigandChemical structure of BindingDB Monomer ID 727042BDBM727042(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574352BDBM50574352(CHEMBL4876088 | US12252491, Example 19)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727041BDBM727041(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574355BDBM50574355(CHEMBL4874078 | US12252491, Example 26)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574356BDBM50574356(CHEMBL4845695 | US12252491, Example 27)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727048BDBM727048(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[(1S)-2-methoxy...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727049BDBM727049(4-Cyclopropyl-N—[(S)-(4,4-difluorocyclohexyl)-[7-[...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727047BDBM727047(N—[(S)-(4,4-difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574353BDBM50574353(CHEMBL4860250 | US12252491, Example 20)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574354BDBM50574354(CHEMBL4866932 | US12252491, Example 21)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 50574357BDBM50574357(CHEMBL4855085 | US12252491, Example 28)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727035BDBM727035(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726971BDBM726971(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 9.45nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726976BDBM726976(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 10.6nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727046BDBM727046(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 11.4nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726969BDBM726969(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 13nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726828BDBM726828(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 15.2nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726975BDBM726975(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 15.5nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726720BDBM726720(3-Cyclopropyl-N—[(S)-(4,4-difluorocyclohexyl)-[7-[...)
Affinity DataIC50: 15.7nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727036BDBM727036(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 18.1nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727040BDBM727040(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 19.3nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726970BDBM726970(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 20nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726905BDBM726905(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 27.7nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727038BDBM727038(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 36.1nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726974BDBM726974(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 37.8nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 726978BDBM726978(3-(3,3-Difluorocyclobutyl)-N—[(S)-(4,4-difluorocyc...)
Affinity DataIC50: 47nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727037BDBM727037(3-[Cyclopropyl(difluoro)methyl]-N—[(S)-(4,4-difluo...)
Affinity DataIC50: 47.1nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 727039BDBM727039(N—[(S)-(4,4-Difluorocyclohexyl)-[7-[[(4S)-2-oxo-4-...)
Affinity DataIC50: 51.9nMAssay Description:The ability of compounds to inhibit the binding of IL-17A to IL-17RA may be assessed with an AlphaLISA assay. Expression and purification of protein ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/22/2025
Entry Details
US Patent