Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 12791
TargetPhenylalanine-4-hydroxylase(Human)
Som Innovation Biotech

US Patent
LigandPNGBDBM729096(US12257253, Compound Hydrastinine)
Affinity DataKd:  2.99E+3nMAssay Description:ITC experiments were performed at 25° C. using a MicroCal PEAQ-ITC microcalorimeter (Malvern). PAH proteins were prepared in a HEPES buffer (HEPES 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/29/2025
Entry Details
US Patent

TargetPhenylalanine-4-hydroxylase(Human)
Som Innovation Biotech

US Patent
LigandPNGBDBM6644(Pteridine deriv. 11 | 6-phenylpteridine-2,4,7-tria...)
Affinity DataKd:  3.03E+3nMAssay Description:ITC experiments were performed at 25° C. using a MicroCal PEAQ-ITC microcalorimeter (Malvern). PAH proteins were prepared in a HEPES buffer (HEPES 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2025
Entry Details
US Patent

TargetPhenylalanine-4-hydroxylase(Human)
Som Innovation Biotech

US Patent
LigandPNGBDBM50373697(Sapropterin | TETRAHYDROBIOPTERIN | US12257253, Co...)
Affinity DataKd:  4.07E+4nMAssay Description:ITC experiments were performed at 25° C. using a MicroCal PEAQ-ITC microcalorimeter (Malvern). PAH proteins were prepared in a HEPES buffer (HEPES 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2025
Entry Details
US Patent