Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 12908
TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739683BDBM739683((R)-1-(3-((3-(cyclopent-1-en-1-yl)-1H-pyrrolo[2,3-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739682BDBM739682((R)-1-(3-((3-cyclopentyl-1H-pyrrolo[2,3-b]pyridin-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739681BDBM739681(1-((3R)-3-((5-(2,2-difluorocyclopropyl)-7H- pyrrol...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739680BDBM739680(1-((R)-3-((5-((1R,2R)-2-(methoxymethyl)cyclopropyl...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739678BDBM739678(1-((2S,5R)-5-((5-(cyclopropylmethyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739677BDBM739677((R)-1-(3-((5-(1-methylcyclopropyl)-7H-pyrrolo[2,3-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739676BDBM739676((R)-1-(3-((3-(cyclopentylmethyl)-1H-pyrrolo[2,3- b...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739690BDBM739690(1-((2S,5R)-5-((5-((3-ethylcyclopentyl)methyl)-7H- ...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739689BDBM739689(1-((2S,5R)-5-((3-(cyclopropylmethyl)-1H-pyrrolo[2,...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739688BDBM739688(1-((2S,5R)-5-((3-(cyclopropanecarbonyl)-1H- pyrrol...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739686BDBM739686(1-((2S,5R)-5-((5-(cyclopropanecarbonyl)-7H- pyrrol...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739685BDBM739685(tert-butyl 4-(((3R,6S)-1-acryloyl-6-methylpiperidi...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739684BDBM739684(1-((2S,5R)-5-((5-cyclopentyl-7H-pyrrolo[2,3- d]pyr...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739662BDBM739662((R)-1-(3-((3-(cyclopropanecarbonyl)-1H-pyrrolo[2,3...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739674BDBM739674((R)-1-(3-((5-(cyclobutylmethyl)-7H-pyrrolo[2,3- d]...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739673BDBM739673((R)-1-(3-((3-(cyclopropylmethyl)-1H-pyrrolo[2,3- b...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739672BDBM739672((R)-1-(3-((5-(cyclopropylmethyl)-7H-pyrrolo[2,3- d...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739671BDBM739671(1-((2S,5R)-5-((5-(cyclobutanecarbonyl)-7H- pyrrolo...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739670BDBM739670(isobutyl 4-(((3R,6S)-1-acryloyl-6-methylpiperidin-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739667BDBM739667((R)-1-(3-((3-(1-methylcyclopropane-1-carbonyl)-1H-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739713BDBM739713((E)-1-((2S,5R)-5-((5-((R)-2,2-difluorocyclopropyl)...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739709BDBM739709(1-((2S,5R)-5-((5-((1R,3R)-2,2-difluoro-3- methylcy...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739708BDBM739708(1-((2S,5R)-5-((5-((1S,3S)-2,2-difluoro-3- methylcy...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739723BDBM739723(1-((2R)-5-((5-((S)-2,2-difluorocyclopropyl)-7H- py...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739721BDBM739721(1-((2S,5R)-5-((5-((S)-2,2-difluorocyclopropyl)-7H-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739718BDBM739718(1-((2S,5S)-5-((5-((R)-2,2-difluorocyclopropyl)-7H-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739699BDBM739699(1-((2S,5R)-5-((5-((1R,2R)-2- (methoxymethyl)cyclop...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739698BDBM739698(1-((2S,5R)-5-((5-(2-(methoxymethyl)cyclopropyl)-7H...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739696BDBM739696(1-((2S,5S)-5-((5-(cyclopropylmethyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739693BDBM739693(1-((2R,5S)-5-((5-(cyclopropylmethyl)-7H-pyrrolo[2,...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739692BDBM739692(1-(5-((5-(cyclopropylmethyl)-7H-pyrrolo[2,3- d]pyr...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739707BDBM739707(1-((2S,5R)-5-((5-((R)-2,2-difluoro-3,3- dimethylcy...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739706BDBM739706(1-((2S,5R)-5-((5-((1R,3S)-2,2-difluoro-3- methylcy...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739705BDBM739705(1-((2S,5R)-5-((5-((1S,3R)-2,2-difluoro-3- methylcy...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739704BDBM739704(1-((2S,5R)-5-((5-(2,2-difluoro-1-methylcyclopropyl...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739703BDBM739703(1-((2S,5R)-5-((5-((S)-2,2-difluorocyclopropyl)-7H-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739702BDBM739702(1-((2S,5R)-5-((5-((R)-2,2-difluorocyclopropyl)-7H-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739701BDBM739701(1-((2S,5R)-5-((5-(2,2-difluorocyclopropyl)-7H- pyr...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739700BDBM739700(1-((2S,5R)-5-((5-((1S,2S)-2- (methoxymethyl)cyclop...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739731BDBM739731(ethyl 5-((1-acryloylpiperidin-4-yl)amino)-1H-pyrro...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739730BDBM739730(1-((R)-3-((5-((1S,5R)-6,6-difluorobicyclo[3.1.0]he...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739729BDBM739729(1-((R)-3-((5-((1R,5S)-6,6-difluorobicyclo[3.1.0]he...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739728BDBM739728(1-((2S,5R)-5-((3-((1R,2R)-2- (methoxymethyl)cyclop...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739726BDBM739726(1-((2S,5R)-5-((3-((S)-2,2-difluorocyclopropyl)-1H-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739725BDBM739725(1-((2S,5R)-5-((3-((R)-2,2-difluorocyclopropyl)-1H-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739735BDBM739735(1-(4-((7-(cyclobutanecarbonyl)-5H-pyrrolo[2,3-b]py...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739734BDBM739734(1-(4-((7-(cyclopropanecarbonyl)-5H-pyrrolo[2,3-b]p...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739732BDBM739732(ethyl 2-((1-acryloylpiperidin-4--yl)amino)-5H-pyrr...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739657BDBM739657(isopropyl 4-(((3R,6S)-1-acryloyl-6-methylpiperidin...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Aclaris Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 739656BDBM739656(propyl 4-(((3R,6S)-1-acryloyl-6-methylpiperidin-3-...)
Affinity DataIC50: 10nMAssay Description:The ability of candidate compounds to interact with JAK3 is quantitated by a mobility shift assay using an LC3000 instrument developed by Caliper Lif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/11/2025
Entry Details
US Patent

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