Compile Data Set for Download or QSAR
Report error Found 129 Enz. Inhib. hit(s) with all data for entry = 13047
LigandPNGBDBM755028(3-[7-chloro-8-(trifluoromethyl)-4H-[1,2,4]triazolo...)
Affinity DataKi:  0.270nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  0.340nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755021(3-(7,8-dichloro-1-methyl-4H-[1,2,4]triazolo[4,3-a]...)
Affinity DataKi:  0.360nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755022(4-fluoro-3-[(4S)-7,8-dichloro-1,4-dimethyl-4H-[1,2...)
Affinity DataKi:  0.380nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755024(8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5H-pyri...)
Affinity DataKi:  0.390nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755023((5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-...)
Affinity DataKi:  0.390nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755031(3-(7,8-dichloro-1-methyl-4H-[1,2,4]triazolo[4,3-a]...)
Affinity DataKi:  0.400nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755026(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methyl-7-...)
Affinity DataKi:  0.440nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755030(6,7-dichloro-5-(2,6-difluoro-3-hydroxy-phenyl)-1-m...)
Affinity DataKi:  0.460nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  0.530nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755033([7-chloro-6-(2-fluoro-5-hydroxy-phenyl)-8-(trifluo...)
Affinity DataKi:  0.850nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755032(8,9-dichloro-7-(2,6-difluoro-3-hydroxy-phenyl)-5H-...)
Affinity DataKi:  0.850nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755027(3-[7-chloro-1-methyl-8-(trifluoromethyl)-4H-[1,2,4...)
Affinity DataKi:  0.860nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755035(4-fluoro-3-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  0.990nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755034([7-chloro-6-(2-fluoro-5-hydroxy-phenyl)-8-(trifluo...)
Affinity DataKi:  1.04nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755028(3-[7-chloro-8-(trifluoromethyl)-4H-[1,2,4]triazolo...)
Affinity DataKi:  1.04nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  1.10nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755036((5S)-8,9-dichloro-7-(2,6-difluoro-3-hydroxy-phenyl...)
Affinity DataKi:  1.30nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755023((5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-...)
Affinity DataKi:  1.40nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755025([7,8-dichloro-6-(2-fluoro-5-hydroxy-phenyl)-4H-[1,...)
Affinity DataKi:  1.40nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755021(3-(7,8-dichloro-1-methyl-4H-[1,2,4]triazolo[4,3-a]...)
Affinity DataKi:  1.45nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  1.49nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM50001765(Halcion | CHEMBL646 | 8-chloro-6-(2-chlorophenyl)-...)
Affinity DataKi:  1.5nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM513333(US11091471, Example RE-A | US20240279218, Example ...)
Affinity DataKi:  1.5nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755029(8-chloro-7-(2-fluoro-5-hydroxy-phenyl)-9-(trifluor...)
Affinity DataKi:  1.54nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755035(4-fluoro-3-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  1.75nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755029(8-chloro-7-(2-fluoro-5-hydroxy-phenyl)-9-(trifluor...)
Affinity DataKi:  1.88nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM513334(US11091471, Example RE-B | US20240279218, Example ...)
Affinity DataKi:  1.90nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755022(4-fluoro-3-[(4S)-7,8-dichloro-1,4-dimethyl-4H-[1,2...)
Affinity DataKi:  1.99nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755046(6-[(4S)-7-chloro-2,4-dimethyl-8-(trifluoromethyl)-...)
Affinity DataKi:  2.07nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755037(2,4-difluoro-3-[(4S)-7,8-dichloro-1,4-dimethyl-4H-...)
Affinity DataKi:  2.12nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755030(6,7-dichloro-5-(2,6-difluoro-3-hydroxy-phenyl)-1-m...)
Affinity DataKi:  2.12nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755024(8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5H-pyri...)
Affinity DataKi:  2.18nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755025([7,8-dichloro-6-(2-fluoro-5-hydroxy-phenyl)-4H-[1,...)
Affinity DataKi:  2.22nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.27nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.27nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755043(6-[(4S)-7-chloro-2,4-dimethyl-8-(trifluoromethyl)-...)
Affinity DataKi:  2.32nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755026(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methyl-7-...)
Affinity DataKi:  2.35nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755045(5-chloro-6-[(4S)-7-chloro-2,4-dimethyl-8-(trifluor...)
Affinity DataKi:  2.80nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM513333(US11091471, Example RE-A | US20240279218, Example ...)
Affinity DataKi:  2.80nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.90nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719133(6,7-dichloro-5-(2-fluoro-5-hydroxy-phenyl)-1-methy...)
Affinity DataKi:  2.90nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755041(6-[(4S)-7-chloro-1,4-dimethyl-8-(trifluoromethyl)-...)
Affinity DataKi:  3.08nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755037(2,4-difluoro-3-[(4S)-7,8-dichloro-1,4-dimethyl-4H-...)
Affinity DataKi:  3.12nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755027(3-[7-chloro-1-methyl-8-(trifluoromethyl)-4H-[1,2,4...)
Affinity DataKi:  3.25nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755044(5-chloro-6-[(4S)-7-chloro-1,4-dimethyl-8-(trifluor...)
Affinity DataKi:  3.25nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755023((5S)-8,9-dichloro-7-(2-fluoro-5-hydroxy-phenyl)-5-...)
Affinity DataKi:  3.30nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755022(4-fluoro-3-[(4S)-7,8-dichloro-1,4-dimethyl-4H-[1,2...)
Affinity DataKi:  3.35nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM719134(6-chloro-5-(2-fluoro-5-hydroxy-phenyl)-1,7-dimethy...)
Affinity DataKi:  3.49nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

LigandPNGBDBM755034([7-chloro-6-(2-fluoro-5-hydroxy-phenyl)-8-(trifluo...)
Affinity DataKi:  3.60nMAssay Description:Radioligand binding assays were carried out in a volume of 200 μL (96-well plates) which contained 100 μL of cell membranes, [3H]RO7239181 at a conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

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