Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 13095
TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757725(US12358911, Compound 10)
Affinity DataIC50: 5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757721(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757724(7-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-...)
Affinity DataIC50: 7.5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757721(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 7.5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757717(amino)-N-hydroxypyrimidine-5-carboxamide | US1235...)
Affinity DataIC50: 7.5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757723(amino)-N-hydroxybenzamide | US12358911, Compound ...)
Affinity DataIC50: 10nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757722(pyridin-3-yl)-N-hydroxypiperidine-4-carboxamide |...)
Affinity DataIC50: 10nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757717(amino)-N-hydroxypyrimidine-5-carboxamide | US1235...)
Affinity DataIC50: 10nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757721(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 10nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757720(5-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 10nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757724(7-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-...)
Affinity DataIC50: 17.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757719(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 17.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757718((E)-3-(4-(((6-((6-acetyl-8-cyclopentyl-5-methyl-7-...)
Affinity DataIC50: 17.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757725(US12358911, Compound 10)
Affinity DataIC50: 17.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757725(US12358911, Compound 10)
Affinity DataIC50: 30nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757724(7-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-...)
Affinity DataIC50: 30nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757718((E)-3-(4-(((6-((6-acetyl-8-cyclopentyl-5-methyl-7-...)
Affinity DataIC50: 30nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757717(amino)-N-hydroxypyrimidine-5-carboxamide | US1235...)
Affinity DataIC50: 30nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757724(7-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-...)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757723(amino)-N-hydroxybenzamide | US12358911, Compound ...)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757717(amino)-N-hydroxypyrimidine-5-carboxamide | US1235...)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757722(pyridin-3-yl)-N-hydroxypiperidine-4-carboxamide |...)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757721(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757725(US12358911, Compound 10)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757720(5-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757719(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 37.5nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 1(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757719(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 62.5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757718((E)-3-(4-(((6-((6-acetyl-8-cyclopentyl-5-methyl-7-...)
Affinity DataIC50: 62.5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757718((E)-3-(4-(((6-((6-acetyl-8-cyclopentyl-5-methyl-7-...)
Affinity DataIC50: 75nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757719(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 87.5nMAssay Description:The inhibitory effect of compounds on HDAC-1 and HDAC-6 function was determined in vitro using an optimized homogenous assay performed in 384-well pl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757718((E)-3-(4-(((6-((6-acetyl-8-cyclopentyl-5-methyl-7-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757722(pyridin-3-yl)-N-hydroxypiperidine-4-carboxamide |...)
Affinity DataIC50: 2.00E+3nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757721(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757719(6-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757723(amino)-N-hydroxybenzamide | US12358911, Compound ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757720(5-((2-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757724(7-((6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757717(amino)-N-hydroxypyrimidine-5-carboxamide | US1235...)
Affinity DataIC50: 1.00E+4nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
Hangzhou Innogate Pharma

US Patent
LigandPNGBDBM757725(US12358911, Compound 10)
Affinity DataIC50: 1.00E+4nMAssay Description:Method 1: In vitro enzymatic activity of the CDK isoforms CDK2/CycA2, CDK4/CycD3 and CDK6/cycD3 were measured using Mobility Shift Assay that monitor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/29/2025
Entry Details
US Patent