Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 13133
TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50119287(CHEMBL3617543 | US12377086, Compound 51)
Affinity DataKi:  20nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataKi:  250nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataKi:  280nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50119287(CHEMBL3617543 | US12377086, Compound 51)
Affinity DataIC50: 310nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataKi:  350nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM32203(cid_1923 | CHEMBL310555 | 8-quinolinol | quinolin-...)
Affinity DataKi:  360nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM50119287(CHEMBL3617543 | US12377086, Compound 51)
Affinity DataKi:  420nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataKi:  490nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataKi:  530nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataKi:  580nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM50361473(CHEMBL1435274 | US12377086, Compound 44)
Affinity DataKi:  660nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32203(cid_1923 | CHEMBL310555 | 8-quinolinol | quinolin-...)
Affinity DataKi:  670nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50361473(CHEMBL1435274 | US12377086, Compound 44)
Affinity DataKi:  670nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 670nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataIC50: 740nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM50370827(CHEMBL374569 | US12377086, Compound 45)
Affinity DataIC50: 760nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM50119287(CHEMBL3617543 | US12377086, Compound 51)
Affinity DataIC50: 810nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32142(cid_416002 | 5-amino-8-quinolinol | AS-0308-225 | ...)
Affinity DataKi:  880nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM76301(5,7-dibromo-8-quinolinol | MLS002207288 | cid_2453...)
Affinity DataKi:  900nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM76301(5,7-dibromo-8-quinolinol | MLS002207288 | cid_2453...)
Affinity DataKi:  920nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM76305(MLS002695956 | cid_2817 | 5-chloro-8-quinolinol | ...)
Affinity DataKi:  960nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM76302(cid_6301 | SMR001549973 | MLS002695929 | 5,7-dichl...)
Affinity DataKi:  960nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM32142(cid_416002 | 5-amino-8-quinolinol | AS-0308-225 | ...)
Affinity DataKi:  990nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM64987(SMR000059036 | MLS000069750 | cid_19910 | nitroxol...)
Affinity DataIC50: 1.00E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM76302(cid_6301 | SMR001549973 | MLS002695929 | 5,7-dichl...)
Affinity DataKi:  1.10E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32147(AS-229 | cid_2722 | CHLOROXINE | US12377086, Compo...)
Affinity DataKi:  1.10E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32188(cid_2788 | TG2-36-2 | CLIOQUINOL | Clioquinol (CQ)...)
Affinity DataKi:  1.10E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM32188(cid_2788 | TG2-36-2 | CLIOQUINOL | Clioquinol (CQ)...)
Affinity DataKi:  1.20E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM32147(AS-229 | cid_2722 | CHLOROXINE | US12377086, Compo...)
Affinity DataKi:  1.30E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM76305(MLS002695956 | cid_2817 | 5-chloro-8-quinolinol | ...)
Affinity DataKi:  1.40E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataIC50: 1.60E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM32142(cid_416002 | 5-amino-8-quinolinol | AS-0308-225 | ...)
Affinity DataIC50: 1.70E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM761675(US12377086, Compound 43)
Affinity DataIC50: 1.90E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM50361473(CHEMBL1435274 | US12377086, Compound 44)
Affinity DataIC50: 1.90E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM50361473(CHEMBL1435274 | US12377086, Compound 44)
Affinity DataIC50: 2.20E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM32203(cid_1923 | CHEMBL310555 | 8-quinolinol | quinolin-...)
Affinity DataIC50: 2.30E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM76301(5,7-dibromo-8-quinolinol | MLS002207288 | cid_2453...)
Affinity DataIC50: 3.20E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32203(cid_1923 | CHEMBL310555 | 8-quinolinol | quinolin-...)
Affinity DataIC50: 3.60E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM76301(5,7-dibromo-8-quinolinol | MLS002207288 | cid_2453...)
Affinity DataIC50: 3.80E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32142(cid_416002 | 5-amino-8-quinolinol | AS-0308-225 | ...)
Affinity DataIC50: 3.80E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32147(AS-229 | cid_2722 | CHLOROXINE | US12377086, Compo...)
Affinity DataIC50: 4.10E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM76305(MLS002695956 | cid_2817 | 5-chloro-8-quinolinol | ...)
Affinity DataIC50: 4.10E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM477700(US12377086, Compound 5)
Affinity DataKi:  4.50E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM32188(cid_2788 | TG2-36-2 | CLIOQUINOL | Clioquinol (CQ)...)
Affinity DataIC50: 4.80E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM76302(cid_6301 | SMR001549973 | MLS002695929 | 5,7-dichl...)
Affinity DataIC50: 4.80E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM32188(cid_2788 | TG2-36-2 | CLIOQUINOL | Clioquinol (CQ)...)
Affinity DataIC50: 5.10E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM76305(MLS002695956 | cid_2817 | 5-chloro-8-quinolinol | ...)
Affinity DataIC50: 5.30E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM76302(cid_6301 | SMR001549973 | MLS002695929 | 5,7-dichl...)
Affinity DataIC50: 5.30E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetVIM-2 type metallo-beta-lactamase(Pseudomonas aeruginosa)TBA
LigandPNGBDBM761660(US12377086, Compound 17)
Affinity DataKi:  5.30E+3nMAssay Description:VIM-2 was diluted to 6 μM with 50 mM HEPES, pH 7.5, containing 150 mM NaCl. The diluted protein solution was used to make several 5 mL aliquots. L-Ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetMetallo-beta lactamase [126-247,M154L](Klebsiella pneumoniae)TBA
LigandPNGBDBM761660(US12377086, Compound 17)
Affinity DataKi:  5.80E+3nMAssay Description:Nitrocefin (Cayman, CAS 41906-86-9) was used as the chromogenic substrate for all biochemical assays. The enzymatic activity of purified VIM-2 and ND...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
US Patent

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