Compile Data Set for Download or QSAR
Report error Found 115 Enz. Inhib. hit(s) with all data for entry = 13175
TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM190202(US9175331, 32 | EPZ008337 | US12390472, Example EP...)
Affinity DataIC50: 0.5nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM190202(US9175331, 32 | EPZ008337 | US12390472, Example EP...)
Affinity DataIC50: 0.5nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM190202(US9175331, 32 | EPZ008337 | US12390472, Example EP...)
Affinity DataIC50: 0.5nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764975(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 0.510nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764976(3-(ethyl(tetrahydro-2H-pyran-4-yl) amino)-N-((4-me...)
Affinity DataIC50: 0.510nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764976(3-(ethyl(tetrahydro-2H-pyran-4-yl) amino)-N-((4-me...)
Affinity DataIC50: 0.510nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764975(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 0.510nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764976(3-(ethyl(tetrahydro-2H-pyran-4-yl) amino)-N-((4-me...)
Affinity DataIC50: 0.510nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764975(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 0.520nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM50594148(CHEMBL5207948 | US12390472, Example 91)
Affinity DataIC50: 0.600nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM50594147(CHEMBL5203091 | US12390472, Example 68)
Affinity DataIC50: 0.600nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM50594148(CHEMBL5207948 | US12390472, Example 91)
Affinity DataIC50: 0.700nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM50594148(CHEMBL5207948 | US12390472, Example 91)
Affinity DataIC50: 0.700nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM50594147(CHEMBL5203091 | US12390472, Example 68)
Affinity DataIC50: 1nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM50594147(CHEMBL5203091 | US12390472, Example 68)
Affinity DataIC50: 1.10nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764973(3-((8-oxabicyclo[3.2.1]octan-3-yl)(ethyl) amino)-5...)
Affinity DataIC50: 1.10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764972(3-((4,4-difluorocyclohexyl)(ethyl)amino)-5-(trans-...)
Affinity DataIC50: 1.20nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764968(WO2012142513, Compound 194 | tert-butyl 3-(3-(((4,...)
Affinity DataIC50: 1.30nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764969(WO2012142513, Compound 195 | 5-(azetidin-3-yloxy)-...)
Affinity DataIC50: 1.90nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764968(WO2012142513, Compound 194 | tert-butyl 3-(3-(((4,...)
Affinity DataIC50: 2nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764973(3-((8-oxabicyclo[3.2.1]octan-3-yl)(ethyl) amino)-5...)
Affinity DataIC50: 2nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764933(3-((4,4-difluorocyclohexyl)(ethyl) amino)-N-((4,6-...)
Affinity DataIC50: 2.30nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764972(3-((4,4-difluorocyclohexyl)(ethyl)amino)-5-(trans-...)
Affinity DataIC50: 2.60nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764933(3-((4,4-difluorocyclohexyl)(ethyl) amino)-N-((4,6-...)
Affinity DataIC50: 3nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764978(3-((4,4-difluorocyclohexyl)(ethyl)amino)-N-((4-hyd...)
Affinity DataIC50: 3.10nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764973(3-((8-oxabicyclo[3.2.1]octan-3-yl)(ethyl) amino)-5...)
Affinity DataIC50: 3.30nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764968(WO2012142513, Compound 194 | tert-butyl 3-(3-(((4,...)
Affinity DataIC50: 3.40nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764969(WO2012142513, Compound 195 | 5-(azetidin-3-yloxy)-...)
Affinity DataIC50: 3.70nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764969(WO2012142513, Compound 195 | 5-(azetidin-3-yloxy)-...)
Affinity DataIC50: 4.90nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641N]()
Evopoint Biosciences

US Patent
LigandPNGBDBM764933(3-((4,4-difluorocyclohexyl)(ethyl) amino)-N-((4,6-...)
Affinity DataIC50: 5.20nMAssay Description:ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of DMSO was 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764972(3-((4,4-difluorocyclohexyl)(ethyl)amino)-5-(trans-...)
Affinity DataIC50: 5.5nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764905(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764925(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764912(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764934(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764915(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764947(2-chloro-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin...)
Affinity DataIC50: 10nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2 [Y641F](Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764978(3-((4,4-difluorocyclohexyl)(ethyl)amino)-N-((4-hyd...)
Affinity DataIC50: 14nMAssay Description:Table 4: ProceduresCompounds at different concentrations were dissolved in 100% DMSO and transferred to test plates, and the final concentration of D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764978(3-((4,4-difluorocyclohexyl)(ethyl)amino)-N-((4-hyd...)
Affinity DataIC50: 21nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764961(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764962(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764959(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764960(methyl 4-((2-(3-(((4,6-dimethyl-2-oxo-1,2-dihydrop...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764966(2-chloro-3-(ethyl(tetrahydro-2H-pyran-4-yl)amino)-...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764963(2-chloro-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764889(5-cyclobutoxy-N-((4,6-dimethyl-2-oxo-1,2-dihydropy...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764890(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764894(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764891(5-(3,3-difluorocyclobutoxy)-N-((4,6-dimethyl-2-oxo...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetHistone-lysine N-methyltransferase EZH2(Human)
Evopoint Biosciences

US Patent
LigandPNGBDBM764892(N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)met...)
Affinity DataIC50: 55nMAssay Description:Table 1: Test ConditionsEZH2 enzyme complex: 25 ng/uLHistone H3 peptide substrate: 4 uMSAM: 2 uMReaction time: 300 minProcedures1. Each compound disc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

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