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Found
27
Enz. Inhib. hit(s) with all data for entry = 13179
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765063
(US12391669, Compound 47)
Copy SMILES
Affinity Data
IC50: 10nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765075
(US12391669, Compound 25)
Copy SMILES
Affinity Data
IC50: 32nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765078
(US12391669, Compound 20)
Copy SMILES
Affinity Data
IC50: 52nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765079
(US12391669, Compound 67)
Copy SMILES
Affinity Data
IC50: 63nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765062
(US12391669, Compound 96)
Copy SMILES
Affinity Data
IC50: 98nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765075
(US12391669, Compound 25)
Copy SMILES
Affinity Data
IC50: 117nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765085
(salt | US12391669, Compound 11)
Copy SMILES
Affinity Data
IC50: 119nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765062
(US12391669, Compound 96)
Copy SMILES
Affinity Data
IC50: 120nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765063
(US12391669, Compound 47)
Copy SMILES
Affinity Data
IC50: 181nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765077
(US12391669, Compound 16)
Copy SMILES
Affinity Data
IC50: 228nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765074
(US12391669, Compound 84)
Copy SMILES
Affinity Data
IC50: 296nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765071
(US12391669, Compound 30)
Copy SMILES
Affinity Data
IC50: 439nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765081
(US12391669, Compound 35)
Copy SMILES
Affinity Data
IC50: 443nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765083
(US12391669, Compound 51)
Copy SMILES
Affinity Data
IC50: 524nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765076
(US12391669, Compound 73)
Copy SMILES
Affinity Data
IC50: 961nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765082
(US12391669, Compound 39)
Copy SMILES
Affinity Data
IC50: 1.14E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765076
(US12391669, Compound 73)
Copy SMILES
Affinity Data
IC50: 1.57E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765080
(US12391669, Compound 43)
Copy SMILES
Affinity Data
IC50: 1.60E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765074
(US12391669, Compound 84)
Copy SMILES
Affinity Data
IC50: 1.98E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765064
(US12391669, Compound 77)
Copy SMILES
Affinity Data
IC50: 2.10E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765084
(US12391669, Compound 55)
Copy SMILES
Affinity Data
IC50: 3.19E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765064
(US12391669, Compound 77)
Copy SMILES
Affinity Data
IC50: 6.20E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE1
(Human)
University Of California
US Patent
Ligand
BDBM765067
(US12391669, Compound 88)
Copy SMILES
Affinity Data
IC50: 7.30E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765071
(US12391669, Compound 30)
Copy SMILES
Affinity Data
IC50: 8.40E+3nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765077
(US12391669, Compound 16)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765078
(US12391669, Compound 20)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL
Target
Serine/threonine-protein kinase/endoribonuclease IRE2
(Human)
University Of California
US Patent
Ligand
BDBM765067
(US12391669, Compound 88)
Copy SMILES
Affinity Data
IC50: 1.00E+4nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
Copy BDB DOI
US Patent
Copy reaction URL