Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 13182
TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765231(N-(3-((2-((3-Fluoro-4-(1-methylpiperidin-4-yl)phen...)
Affinity DataIC50: 0.700nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50557395(CHEMBL4762807 | US20240140952, Compound 7 | US1239...)
Affinity DataIC50: 1.10nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM601867(US11643396, Example SG2-082 | US12391676, ID SY3-0...)
Affinity DataIC50: 1.60nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765232(N-(3-((2-((3-Fluoro-5-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 3.10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM81541(US20240140952, Compound 6 | US12391676, ID MA9-060)
Affinity DataIC50: 3.30nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM50557395(CHEMBL4762807 | US20240140952, Compound 7 | US1239...)
Affinity DataIC50: 6.40nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM601871(US11643396, Example SG3-111 | US12391676, ID MA9-0...)
Affinity DataIC50: 8.20nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765235(N-(2-Chloro-5-((2-((3-fluoro-5-(4-methylpiperazin-...)
Affinity DataIC50: 17nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM81541(US20240140952, Compound 6 | US12391676, ID MA9-060)
Affinity DataIC50: 26nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765235(N-(2-Chloro-5-((2-((3-fluoro-5-(4-methylpiperazin-...)
Affinity DataIC50: 49nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765231(N-(3-((2-((3-Fluoro-4-(1-methylpiperidin-4-yl)phen...)
Affinity DataIC50: 87nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765232(N-(3-((2-((3-Fluoro-5-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 127nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM601871(US11643396, Example SG3-111 | US12391676, ID MA9-0...)
Affinity DataIC50: 143nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765137(N-(3-((2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent

TargetBromodomain-containing protein 4(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM765137(N-(3-((2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phen...)
Affinity DataIC50: 3.96E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/25/2025
Entry Details
US Patent