Compile Data Set for Download or QSAR
Report error Found 174 Enz. Inhib. hit(s) with all data for entry = 13277
TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719814(2-hydroxy-N-methyl-N-((5-(2-((2- methyl-6-(trifluo...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719730(N-(2-(5-(2-((2- (trifluoromethyl)quinazolin-4- yl)...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719815(2-hydroxy-N-((5-(2-((5- (trifluoromethyl)oxazolo[5...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719812(2,2-difluoro-N-((5-(2-((2- (trifluoromethyl)pyrido...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719729(N-((3-fluoro-5-(2-((1-methyl-1H- pyrazolo[3,4-d]py...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719732(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719817(2-hydroxy-N-((5-(2-((2-methyl-6- (trifluoromethyl)...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719731(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719816(2-hydroxy-N-((5-(2-((6- (trifluoromethyl)oxazolo[4...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719733(N-methyl-N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]py...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719823(2-hydroxy-N-((5-(2-((1-(2- methoxyethyl)-6-(triflu...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719981(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719822(N-((5-(2-((6-fluoro-2- methylpyrido[2,3-d]pyrimidi...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719735(N-((5-(2-((2-methylquinazolin-4- yl)thio)acetyl)th...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719830(2-hydroxy-N-((5-(2-((2-(2- methoxyethyl)-6-(triflu...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719734(N-methyl-N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]py...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719824(2-hydroxy-N-((5-(2-((2-methyl-6- (trifluoromethoxy...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719772(2-hydroxy-N-((5-(2-((1-methyl-6- (trifluoromethyl)...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719720(N-((5-(2-((2- (difluoromethyl)quinazolin-4- yl)thi...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719771(N-((5-(2-((6-chloro-7-fluoro-2- methylquinazolin-4...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719717(N-((5-(2-((2- (dimethylamino)quinazolin-4- yl)thio...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719774(2-hydroxy-N-((5-(2-((2-methyl-6- (trifluoromethyl)...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719722(N-((5-(2-((6-(difluoromethyl)-1- methyl-1H-pyrazol...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719773(N-((5-(2-((7-fluoro-6-methoxy-2- methylquinazolin-...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719721(N-((5-(2-((1-methyl-6- (trifluoromethyl)-1H-pyrazo...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719783(2-hydroxy-N-((5-(2-((2-methyl-6- (4-methylpiperazi...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719725(3-methyl-1-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]py...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719777(N-((5-(2-((2-cyclopropyl-6- (trifluoromethyl)-2H-p...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719724(N-((5-(2-((5-methyloxazolo[4,5- b]pyridin-2- yl)th...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719811(2-hydroxy-N-((5-(2-((2- (trifluoromethyl)pyrido[2,...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719727(1-(2-(5-(2-((2- (trifluoromethyl)quinazolin-4- yl)...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719806(N-((5-(2-((8-fluoro-6-methoxy-2- methylquinazolin-...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719726(1-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719807(2-hydroxy-N-((5-(2-((6-methoxy- 2-methylquinazolin...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719858(N-((5-(2-((5-fluoro-6-methoxy-2- methylquinazolin-...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719788(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719859(2-hydroxy-N-((5-(2-((6-methoxy- 2-(trifluoromethyl...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719851(2-hydroxy-N-((5-(2-((2- methylpyrido[3,2-d]pyrimid...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719785(N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]pyrimidin-4...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719854(2-hydroxy-N-((5-(2-((6-methoxy- 2-(trifluoromethyl...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719864(N-((5-(2-((2-(difluoromethyl)-6- methoxypyrido[2,3...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719790(N-methyl-N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]py...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719701(N-((5-(2-((2-isopropylquinazolin- 4-yl)thio)acetyl...)
Affinity DataIC50: 100nMAssay Description:Table 9: Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a bacul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719860(N-((5-(2-((6-ethoxy-2- methylpyrido[2,3-d]pyrimidi...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719789(N-methyl-N-((5-(2-((1-methyl-1H- pyrazolo[3,4-d]py...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719863(2-methoxy-N-((5-(2-((6-methoxy- 2-methylpyrido[2,3...)
Affinity DataIC50: 100nMAssay Description:Table 8: Dose response testing of HDAC6 and HDAC 1 were run at Reaction Biology Corporation (RBC). Inhibition of HDAC enzymes was performed using N-t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719792(N-(2-(5-(2-((2-methylquinazolin-4- yl)thio)acetyl)...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719704(N-((5-(2-((2-methylquinazolin-4- yl)thio)acetyl)th...)
Affinity DataIC50: 100nMAssay Description:Table 9: Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a bacul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719791(1-cyclopropyl-N-((5-(2-((2- methylquinazolin-4- yl...)
Affinity DataIC50: 100nMAssay Description:Compounds were tested in biochemical protein-protein interaction assays to determine if they can specifically block the interaction between the extra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Augustine Therapeutics

US Patent
LigandPNGBDBM719703(N-((5-(2-((2- cyclopropylquinazolin-4- yl)thio)ace...)
Affinity DataIC50: 100nMAssay Description:Table 9: Inhibition of HDAC enzymes was performed in 384-well plate format using human full-length recombinant HDAC1 and HDAC6, isolated from a bacul...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/8/2026
Entry Details
US Patent

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