Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 13365
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783826((4S)-8-[3-(3,4-dichloro-2- methyl- 2H-indazol-5-yl...)
Affinity DataIC50: 5.30nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM50557716(CHEMBL4782469 | US12458640, Example 23)
Affinity DataIC50: 5.40nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783819((4S)-8-[3-(4-chloro-2- methyl-2H- indazol-5-yl)-5-...)
Affinity DataIC50: 5.60nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM50557713(CHEMBL4762585 | US12458640, Example 16)
Affinity DataIC50: 7nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM50557712(CHEMBL4759997 | US12458640, Example 8)
Affinity DataIC50: 7.10nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM50557714(CHEMBL4788960 | US12458640, Example 20)
Affinity DataIC50: 7.10nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783828((4S)-8-[3-(4-chloro-2- ethyl-2H- indazol-5-yl)-5-m...)
Affinity DataIC50: 7.60nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783910((1R)-8-[3-(3,4-dichloro-2- methyl-2H-indazol-5-yl)...)
Affinity DataIC50: 7.60nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783913((3S,4S)-8-[3-(3-chloro-2- fluorophenyl)-5-methyl-1...)
Affinity DataIC50: 9.80nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783918({6-[(3S,4S)-4-amino-3- methyl-2-oxa-8-azaspiro[4.5...)
Affinity DataIC50: 11nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM50557711(CHEMBL4777771 | US12458640, Example 7)
Affinity DataIC50: 11nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM50557715(CHEMBL4752044 | US12458640, Example 22)
Affinity DataIC50: 11nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783906((1R)-8-[3-(5-chloro-3- methoxyquinoxalin-6-yl)-5- ...)
Affinity DataIC50: 13nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783912({6-[(3S,4S)-4-amino-3- methyl-2- oxa-8-azaspiro[4....)
Affinity DataIC50: 14nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783905(7-(6-[(1R)-1-amino-8- azaspiro[4.5]decan-8-yl]-5- ...)
Affinity DataIC50: 15nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783915({6-[(3S,4S)-4-amino-3- methyl-2- oxa-8-azaspiro[4....)
Affinity DataIC50: 15nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783812((1R)-8-[3-(4-chloro-2-methyl- 2H- indazol-5-yl)-5-...)
Affinity DataIC50: 17nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783901((3S,4S)-8-[3-(5-chloro-3- methoxyquinoxalin-6-yl)-...)
Affinity DataIC50: 18nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783849((38,4S)-8-[3-(4-chloro-2- methyl-2H-indazol-5-yl)-...)
Affinity DataIC50: 18nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783903((3S,4S)-8-{3-[5-chloro-3- (dimethylamino)quinoxali...)
Affinity DataIC50: 19nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783811((1R,3R)-8-[3-(4-chloro-2- methyl- 2H-indazol-5-yl)...)
Affinity DataIC50: 20nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783919((3S,4S)-8-{3-[3-(azetidin-1-yl)- 5-chloroquinoxali...)
Affinity DataIC50: 24nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Otsuka Pharmaceutical Co.

US Patent
LigandPNGBDBM783920((3S,4S)-8-{3-[5-chloro-3- (morpholin-4-yl)quinoxal...)
Affinity DataIC50: 28nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/24/2026
Entry Details US Patent