Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 13370
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Alcon

US Patent
LigandPNGBDBM783887(US12459956, Compound 7)
Affinity DataIC50: 1.10nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM50557723(CHEMBL4743703 | US12459956, Compound 2)
Affinity DataIC50: 5nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM783883(US12459956, Compound 3)
Affinity DataIC50: 6nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM783884(US12459956, Compound 4)
Affinity DataIC50: 6nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 1(Human)
Alcon

US Patent
LigandPNGBDBM783883(US12459956, Compound 3)
Affinity DataIC50: 7nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM50557726(CHEMBL4776650 | US12459956, Compound 11)
Affinity DataIC50: 7nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Alcon

US Patent
LigandPNGBDBM783886(US12459956, Compound 6)
Affinity DataIC50: 8nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetTyrosine-protein kinase JAK2(Human)
Alcon

US Patent
LigandPNGBDBM783885(US12459956, Compound 5)
Affinity DataIC50: 8.90nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetTyrosine-protein kinase JAK2(Human)
Alcon

US Patent
LigandPNGBDBM569299(US11427563, Compound 54 | US12459956, Compound 9)
Affinity DataIC50: 12nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetTyrosine-protein kinase JAK2(Human)
Alcon

US Patent
LigandPNGBDBM569299(US11427563, Compound 54 | US12459956, Compound 9)
Affinity DataIC50: 12nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM50557727(CHEMBL4749989 | US12459956, Compound 12)
Affinity DataIC50: 12nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM50557728(CHEMBL4761315 | US12459956, Compound 13)
Affinity DataIC50: 18nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetTyrosine-protein kinase JAK2(Human)
Alcon

US Patent
LigandPNGBDBM783884(US12459956, Compound 4)
Affinity DataIC50: 22nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetTyrosine-protein kinase JAK2(Human)
Alcon

US Patent
LigandPNGBDBM783900(US12459956, Compound 22)
Affinity DataIC50: 22nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM783895(US12459956, Compound 17)
Affinity DataIC50: 30nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM783896(US12459956, Compound 18)
Affinity DataIC50: 30nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Alcon

US Patent
LigandPNGBDBM783898(US12459956, Compound 20)
Affinity DataIC50: 35nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 1(Human)
Alcon

US Patent
LigandPNGBDBM783897(US12459956, Compound 19)
Affinity DataIC50: 43nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM783894(US12459956, Compound 16)
Affinity DataIC50: 54nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM783899(US12459956, Compound 21)
Affinity DataIC50: 111nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetRho-associated protein kinase 2(Human)
Alcon

US Patent
LigandPNGBDBM783892(US12459956, Compound 14)
Affinity DataIC50: 230nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent

TargetTyrosine-protein kinase JAK1(Human)
Alcon

US Patent
LigandPNGBDBM783893(US12459956, Compound 15)
Affinity DataIC50: 350nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/23/2026
Entry Details US Patent