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Found
27
Enz. Inhib. hit(s) with all data for entry = 5555
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369192
(6-(2-Aminoanilino)-3H-1,3-benzothiazol-2-one | US1...)
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Affinity Data
Kd: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369207
(3,3-Difluoro-5-(2-isopropylbenzimidazol-1-yl)indol...)
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Affinity Data
Kd: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369213
(5-(2-Isopropylbenzimidazol-1-yl)-1,3-dihydropyrrol...)
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Affinity Data
Kd: <1nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369208
(6-(4-Hydroxyisoindoline-2-carbonyl)-3H-1,3-benzoxa...)
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Affinity Data
Kd: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369190
(2-Isopropyl-N-methyl-1-(2-oxoindolin-6-yl)benzimid...)
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Affinity Data
Kd: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369191
(2-Isopropyl-N-methyl-1-(2-oxoindolin-5-yl)benzimid...)
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Affinity Data
Kd: 3nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM368972
(N-(2-Oxo-3H-1,3-benzoxazol-6-yl)benzamide | US1252...)
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Affinity Data
Kd: 4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369199
(6-(Indoline-1-carbonyl)-3H-1,3-benzoxazol-2-one | ...)
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Affinity Data
Kd: 4nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369198
(N-(1-Acetyl-4-piperidyl)-2-oxo-3H-1,3-benzoxazole-...)
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Affinity Data
Kd: 6nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM368996
(N-(2-Oxoindolin-5-yl)furan-2-carboxamide | US12528...)
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Affinity Data
Kd: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369205
(N-(1-Acetyl-4-piperidyl)-2-oxo-3H-oxazolo[4,5-b]py...)
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Affinity Data
Kd: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369212
(2-Isopropyl-A-methyl-1-(2-oxo-1,3-dihydropyrrolo[2...)
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Affinity Data
Kd: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369194
(6-(2-Aminoanilino)-3H-1,3-benzoxazol-2-one | US125...)
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Affinity Data
Kd: 8nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369206
(5-(Indoline-1-carbonyl)-1,3-dihydropyrrolo[2,3-b]p...)
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Affinity Data
Kd: 13nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369189
(2-(2-Methylphenoxy)-N-(2-oxo-3H-1,3-benzothiazol-6...)
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Affinity Data
Kd: 14nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369209
(6-(4-Nitroisoindoline-2-carbonyl)-3H-1,3-benzoxazo...)
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Affinity Data
Kd: 14nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369203
(5-(Indoline-1-carbonyl)indolin-2-one | US12528797,...)
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Affinity Data
Kd: 15nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369193
(6-(2-Isopropylbenzimidazol-1-yl)-3H-1,3-benzothiaz...)
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Affinity Data
Kd: 19nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369204
(2-Oxo-N-phenyl-3H-oxazolo[4,5-b]pyridine-6-carboxa...)
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Affinity Data
Kd: 24nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369200
(6-(2,3-Dihydropyrrolo[2,3-b]pyridine-1-carbonyl)-3...)
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Affinity Data
Kd: 24nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369202
(6-(Indoline-1-carbonyl)-3H-1,3-benzothiazol-2-one ...)
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Affinity Data
Kd: 28nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369210
(N-(3,3-difluoro-2-oxo-indolin-5-yl)tetralin-1-carb...)
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Affinity Data
Kd: 28nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369211
(N-(3,3-Difluoro-1-oxo-indolin-5-yl)benzofuran-3-ca...)
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Affinity Data
Kd: 52nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369197
(2-Oxo-N-phenyl-3H-1,3-benzoxazole-6-carboxamide | ...)
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Affinity Data
Kd: 54nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369201
(2-Oxo-N-phenyl-3H-1,3-benzothiazole-6-carboxamide ...)
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Affinity Data
Kd: 79nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369196
(2-Oxo-N-phenylindoline-5-carboxamide | US12528797,...)
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Affinity Data
Kd: 91nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL
Target
Protein cereblon
(Human)
C4 Therapeutics
US Patent
Ligand
BDBM369195
(6-(2-Isopropylbenzimidazol-1-yl)-3H-1,3-benzoxazol...)
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Affinity Data
Kd: 108nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Date in BDB:
6/1/2026
Entry Details
US Patent
Copy reaction URL