Compile Data Set for Download or QSAR
Report error Found 151 Enz. Inhib. hit(s) with all data for entry = 7999
LigandChemical structure of BindingDB Monomer ID 791691BDBM791691(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 1nMAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791692BDBM791692((S)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 1nMAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791688BDBM791688(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 2nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791694BDBM791694(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 2nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791676BDBM791676(US12544374, Compound C37)
Affinity DataIC50: 2nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791696BDBM791696((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 3nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791667BDBM791667(US12544374, Compound C28)
Affinity DataIC50: 5nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791715BDBM791715((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 5nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791665BDBM791665(8-chloro-N-(4-(((5-((4-(methylsulfonyl)piperazin-1...)
Affinity DataIC50: 6nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791669BDBM791669(US12544374, Compound C30)
Affinity DataIC50: 7nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791681BDBM791681(US12544374, Compound C42)
Affinity DataIC50: 7nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791688BDBM791688(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 8nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791675BDBM791675(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 9nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791657BDBM791657(2-hydroxyethyl (2-(((4-((8-chloro-1,7-naphthyridin...)
Affinity DataIC50: 10nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791713BDBM791713((S)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 10nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791675BDBM791675(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 11nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791665BDBM791665(8-chloro-N-(4-(((5-((4-(methylsulfonyl)piperazin-1...)
Affinity DataIC50: 12nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791685BDBM791685(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 12nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791716BDBM791716(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 12nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791685BDBM791685(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 13nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791653BDBM791653(2-(2-(((4-((8-methoxy-1,7-naphthyridin-2-yl)amino)...)
Affinity DataIC50: 13nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791696BDBM791696((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 15nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791656BDBM791656(2-methoxyethyl (2-(((4-((8-chloro-1,7-naphthyridin...)
Affinity DataIC50: 15nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791676BDBM791676(US12544374, Compound C37)
Affinity DataIC50: 15nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791692BDBM791692((S)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 15nMAssay Description:The ELISA portion of the assay is performed in a black Maxisorp 96-well plate that is coated overnight at 4° C. with 100 uL/well of the cell lysa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791655BDBM791655(Methyl (2-(((4-((8-chloro-1,7-naphthyridin-2-yl)am...)
Affinity DataIC50: 17nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791669BDBM791669(US12544374, Compound C30)
Affinity DataIC50: 17nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791713BDBM791713((S)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 18nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791690BDBM791690(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 18nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791707BDBM791707(2-((2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)...)
Affinity DataIC50: 18nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791681BDBM791681(US12544374, Compound C42)
Affinity DataIC50: 18nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791666BDBM791666(US12544374, Compound C27)
Affinity DataIC50: 19nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791710BDBM791710((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 19nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791678BDBM791678(US12544374, Compound C39)
Affinity DataIC50: 20nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791668BDBM791668(US12544374, Compound C29)
Affinity DataIC50: 20nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791699BDBM791699(2-(((4-((8-(methylamino)-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 21nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791715BDBM791715((R)-2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 21nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791668BDBM791668(US12544374, Compound C29)
Affinity DataIC50: 22nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791699BDBM791699(2-(((4-((8-(methylamino)-1,7-naphthyridin-2-yl)ami...)
Affinity DataIC50: 22nMAssay Description:Inhibition of cAMP Activity of GPR6 In Vitro AssayThis cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity o...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791664BDBM791664(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)cycl...)
Affinity DataIC50: 23nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791689BDBM791689(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 23nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791674BDBM791674(8-chloro-N-(4-(((5-((oxetan-3-yloxy)methyl)pyrimid...)
Affinity DataIC50: 24nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791677BDBM791677(US12544374, Compound C38)
Affinity DataIC50: 24nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791643BDBM791643(N-(2-(((4-((8-methoxy-1,7-naphthyridin-2-yl)amino)...)
Affinity DataIC50: 25nMAssay Description:To measure cell-based anti-HCV activity of selected compounds of the present invention, replicon cells were seeded at 5000 cells/well in 96-well coll...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791716BDBM791716(2-(2-(((4-((8-chloro-1,7-naphthyridin-2-yl)amino)c...)
Affinity DataIC50: 25nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791670BDBM791670(US12544374, Compound C31)
Affinity DataIC50: 26nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791666BDBM791666(US12544374, Compound C27)
Affinity DataIC50: 27nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791674BDBM791674(8-chloro-N-(4-(((5-((oxetan-3-yloxy)methyl)pyrimid...)
Affinity DataIC50: 27nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791687BDBM791687(8-chloro-N-(4-(((5-(2-(oxetan-3-ylamino)ethyl)pyri...)
Affinity DataIC50: 27nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

LigandChemical structure of BindingDB Monomer ID 791656BDBM791656(2-methoxyethyl (2-(((4-((8-chloro-1,7-naphthyridin...)
Affinity DataIC50: 27nMAssay Description:Accumulation of intracellular cAMP was examined as a measure of the ability of the peptides of the present invention to elicit a functional response ...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/22/2026
Entry Details US Patent

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