Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 13435
Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793462BDBM793462((3S,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-y...)
Affinity DataKi:  0.00200nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793410BDBM793410(7-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  0.0280nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 139370BDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataKi:  0.0360nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent
PDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793465BDBM793465(4-[(4-cyclopropoxyphenyl)methyl]-7-fluoro-2-(1-met...)
Affinity DataKi:  0.150nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793457BDBM793457((3R,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-y...)
Affinity DataKi:  0.200nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793450BDBM793450(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(cyclopr...)
Affinity DataKi:  0.277nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793458BDBM793458(8-fluoro-2-(1-methylpyrrol-3-yl)-4-[[(4-isobutoxy)...)
Affinity DataKi:  0.410nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793414BDBM793414(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  0.429nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793455BDBM793455(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[3-fluoro-4...)
Affinity DataKi:  0.947nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793465BDBM793465(4-[(4-cyclopropoxyphenyl)methyl]-7-fluoro-2-(1-met...)
Affinity DataKi:  1.33nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793450BDBM793450(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(cyclopr...)
Affinity DataKi:  1.62nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793459BDBM793459(7-chloro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  1.63nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793458BDBM793458(8-fluoro-2-(1-methylpyrrol-3-yl)-4-[[(4-isobutoxy)...)
Affinity DataKi:  1.69nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793461BDBM793461(2-(1-methylpiperidin-4-yl)-4-[[4-(2-methylpropoxy)...)
Affinity DataKi:  1.74nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793453BDBM793453(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[(4-methoxyp...)
Affinity DataKi:  2.03nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793410BDBM793410(7-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  2.40nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793451BDBM793451(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  2.72nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 139370BDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataKi:  2.94nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793453BDBM793453(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[(4-methoxyp...)
Affinity DataKi:  2.99nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793414BDBM793414(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  3.39nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793457BDBM793457((3R,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-y...)
Affinity DataKi:  4.19nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793452BDBM793452(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  5.29nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793463BDBM793463(7,8-difluoro-2-(4-isobutoxybenzyl)-4-(1-methylpipe...)
Affinity DataKi:  5.98nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793455BDBM793455(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[3-fluoro-4...)
Affinity DataKi:  9.36nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793456BDBM793456(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[(6-isoprop...)
Affinity DataKi:  9.78nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793454BDBM793454(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[2-fluoro-4...)
Affinity DataKi:  12.7nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793464BDBM793464(7-fluoro-2-[[4-(2-hydroxy-2-methylpropyl)phenyl]me...)
Affinity DataKi:  18.2nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793464BDBM793464(7-fluoro-2-[[4-(2-hydroxy-2-methylpropyl)phenyl]me...)
Affinity DataKi:  20.1nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793462BDBM793462((3S,4S)-8-fluoro-2-(1-methyl-3-fluoropiperidin-4-y...)
Affinity DataKi:  26.1nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793451BDBM793451(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  27.3nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793452BDBM793452(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  42.4nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793460BDBM793460(7-fluoro-1'-methyl-2-[[4-(2-methylpropoxy)phenyl]m...)
Affinity DataKi:  53.3nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 139370BDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataIC50: 208nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793410BDBM793410(7-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataIC50: 260nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793459BDBM793459(7-chloro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataKi:  486nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793450BDBM793450(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(cyclopr...)
Affinity DataIC50: 1.19E+3nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Jiangsu Nhwa Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 793414BDBM793414(8-fluoro-2-(1-methylpiperidin-4-yl)-4-[[4-(2-methy...)
Affinity DataIC50: 3.17E+3nMAssay Description:HEK293 cell lines stably expressing cloned human NR1/NR2B and NR1/NR2A, respectively, were established according to standard previously described met...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/6/2026
Entry Details
US Patent