Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 912
TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 496962BDBM496962(cmdc.202100576, 23e | US12636275, Compound A5)
Affinity DataIC50: 0.450nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808569BDBM808569(DC406016 | N-((S)-1-(((S)-4-(benzylamino)-3, 4-dio...)
Affinity DataIC50: 0.450nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808571BDBM808571(DC406020 | N-((S)-1-(((S)-4-(benzylamino)-3, 4-dio...)
Affinity DataIC50: 0.470nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808573BDBM808573(DC406067 | N-((S)-1-(((S)-4-(cyclopropylamino)-3, ...)
Affinity DataIC50: 0.570nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808572BDBM808572(DC406068 | N-((S)-1-(((S)-4-(cyclopropylamino)-3, ...)
Affinity DataIC50: 0.630nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808570BDBM808570(DC406009 | N-((S)-1-(((S)-4-(benzylamino)-3, 4-dio...)
Affinity DataIC50: 0.660nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetProcathepsin L(Human)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298298BDBM298298(DC403113 | N-((S)-l-(((S)-4-(benzylamino)-3,4-dion...)
Affinity DataIC50: 1.36nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298298BDBM298298(DC403113 | N-((S)-l-(((S)-4-(benzylamino)-3,4-dion...)
Affinity DataIC50: 2.40E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298310BDBM298310(DC404001 | N-((S)-1-(((S)-4-(benzylamino)-3,4-dion...)
Affinity DataIC50: 3.00E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743443BDBM743443(N-((S)-1-(((S)-4-(benzyl)-3,4-dione-1- (cyclohexyl...)
Affinity DataIC50: 3.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743438BDBM743438(N-((S)-1-(((S)-4-(benzyl)-3,4-dione-1- (isopropyla...)
Affinity DataIC50: 4.50E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 458395BDBM458395(N-((S)-1-(((S)-4-(benzylamino)-3,4-dione-1- ((S)-2...)
Affinity DataIC50: 4.70E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743472BDBM743472(N-((S)-1-(((S)-4-(4-methylbenzylmethylamino)-3, 4-...)
Affinity DataIC50: 4.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743442BDBM743442(N-((S)-l-(((S)-4-(benzyl)-3,4-dione-1- (isopropyla...)
Affinity DataIC50: 4.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 458407BDBM458407(N-((S)-1-(((S)-4-(cyclohexylamino)-3,4-dione- 1-((...)
Affinity DataIC50: 4.90E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743446BDBM743446(N-((S)-1-(((S)-4-(cyclohexylamino)-3, 4-dione-1-((...)
Affinity DataIC50: 5.20E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743459BDBM743459(N-((S)-1-(((S)-4-(benzylamino)-3, 4-dione-1-((S)-2...)
Affinity DataIC50: 5.60E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 458403BDBM458403(N-((S)-1-(((S)-4-(cyclohexylamino)-3,4-dione- 1-((...)
Affinity DataIC50: 5.60E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808563BDBM808563(N-((S)-1-((S)-4-(4-phenylbenzylamino)-3, 4-dione-1...)
Affinity DataIC50: 5.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 458422BDBM458422(N-((S)-1-(((S)-4-(tert-butylamino)-3,4-dione- 1-((...)
Affinity DataIC50: 5.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 458406BDBM458406(N-((S)-1-(((S)-4-(tert-butylamino)-3,4-dione- 1-((...)
Affinity DataIC50: 5.90E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298328BDBM298328(N-((S)-1-(((S)-4-(tert-butylamino)-3,4-dione- 1-((...)
Affinity DataIC50: 6.50E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808567BDBM808567(N-((S)-1-(((S)-4-(benzylamino)-3, 4-dione-1-((S)-2...)
Affinity DataIC50: 6.70E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 458404BDBM458404(N-((S)-1-(((S)-4-(benzylamino)-3,4-dione-1- ((S)-2...)
Affinity DataIC50: 6.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743468BDBM743468(N-((S)-1-(((S)-4-(3,5-difluorobenzylamino)-3, 4-di...)
Affinity DataIC50: 7.60E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808566BDBM808566(N-((S)-1-(((S)-4-(benzylamino)-3, 4-dione-1-((S)-2...)
Affinity DataIC50: 8.50E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743467BDBM743467(N-((S)-1-(((S)-4-(benzylamino)-3, 4-dione-1-((S)-2...)
Affinity DataIC50: 8.80E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 743454BDBM743454(N-((S)-1-(((S)-4-(benzylamino)-3, 4-dione-1-((S)-2...)
Affinity DataIC50: 9.50E+3nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298303BDBM298303(N-((S)-3-cyclohexyl-1-(((S)-4-(cyclohexylami no)-3...)
Affinity DataIC50: 9.80E+3nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 458426BDBM458426(N-((S)-l-(((S)-4-(cyclohexyl)-3,4-dione-1- (isopro...)
Affinity DataIC50: 1.03E+4nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298299BDBM298299(N-((S)-1-(((S)-4-(benzylamino)-3,4-dione-1- ((S)-2...)
Affinity DataIC50: 1.25E+4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298302BDBM298302(N-((S)-1-(((S)-4-(tert-butylamino)-3,4-dione- 1-((...)
Affinity DataIC50: 1.52E+4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808564BDBM808564(N-((S)-1-(((S)-4-(tert-butylamino)-3, 4-dione-1-((...)
Affinity DataIC50: 1.52E+4nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298317BDBM298317(N-((S)-3-cyclohexyl-1-(((S)-4-(cyclohexylamino)- 3...)
Affinity DataIC50: 2.35E+4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298311BDBM298311(N-((S)-3-cyclohexyl-1-(((S)-4-(cyclohexylami no)-3...)
Affinity DataIC50: 2.41E+4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298327BDBM298327(N-((S)-1-(((S)-4-(benzylamino)-3,4-dione-1- ((S)-2...)
Affinity DataIC50: 2.52E+4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 298276BDBM298276(N-((S)-1-(((S)-4-(tert-butylamino)-3,4-dione- 1-((...)
Affinity DataIC50: 2.53E+4nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Shanghai Institute of Materia Medica, Chinese Academy Of Sciences

US Patent
LigandChemical structure of BindingDB Monomer ID 808565BDBM808565(N-((S)-1-(((S)-4-((R)-1-phenyl-ethyl)-amino)- 3,4-...)
Affinity DataIC50: 2.64E+4nMAssay Description:The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
3/11/2019
Entry Details
US Patent