Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 13595
TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809336BDBM809336((S)-6-chloro-2-((5-(3- methylisoxazol-5- yl)pyrimi...)
Affinity DataIC50: 4nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809338BDBM809338((S)-6-chloro-2-((5-(5- methyloxazol-2-yl)pyrimidin...)
Affinity DataIC50: 4nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809337BDBM809337((S)-6-chloro-2-((5-(4- methyloxazol-2-yl)pyrimidin...)
Affinity DataIC50: 8nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809335BDBM809335(US12643890, Example 15)
Affinity DataIC50: 9nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809339BDBM809339((S)-6-chloro-2-((5-(5- methylpyrazin-2-yl)pyrimidi...)
Affinity DataIC50: 10nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809341BDBM809341((S)-6-chloro-2-[[5-(3-methyl- 1,2,4-triazol-1-yl)p...)
Affinity DataIC50: 12nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809340BDBM809340((S)-6-chloro-2-((5-methyl- [2,5$#8243;-bipyrimidin...)
Affinity DataIC50: 14nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809324BDBM809324(US12643890, Example 4)
Affinity DataIC50: 38nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809211BDBM809211(US12643890, Example 1)
Affinity DataIC50: 108nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809323BDBM809323(US12643890, Example 3)
Affinity DataIC50: 108nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809332BDBM809332(US12643890, Example 12)
Affinity DataIC50: 139nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809330BDBM809330(US12643890, Example 10)
Affinity DataIC50: 160nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809326BDBM809326(US12643890, Example 6)
Affinity DataIC50: 163nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809325BDBM809325(US12643890, Example 5)
Affinity DataIC50: 177nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809328BDBM809328(US12643890, Example 8)
Affinity DataIC50: 180nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809334BDBM809334(US12643890, Example 14)
Affinity DataIC50: 216nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809327BDBM809327(US12643890, Example 7)
Affinity DataIC50: 217nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809333BDBM809333(US12643890, Example 13)
Affinity DataIC50: 217nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809322BDBM809322(US12643890, Example 2)
Affinity DataIC50: 221nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809329BDBM809329(US12643890, Example 9)
Affinity DataIC50: 235nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent

TargetAutotaxin(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 809331BDBM809331(US12643890, Example 11)
Affinity DataIC50: 251nMAssay Description:ATX is diluted to 2.2 nM in assay buffer. Choline oxidase and horseradish peroxidase are diluted to 7.3 U/ml and 14.7 U/ml, respectively. 18:1 LPC an...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/19/2026
Entry Details
US Patent