Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 8784
TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519522BDBM519522(US11142505, FAH-74 | US20210101879, Compound FAH-7...)
Affinity DataIC50: 9nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796652BDBM796652(US20210101879, Compound FAH-86)
Affinity DataIC50: 14nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796663BDBM796663(US20210101879, Compound FAH-127)
Affinity DataIC50: 14nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796640BDBM796640(US20210101879, Compound FAH-66)
Affinity DataIC50: 18nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796639BDBM796639(US20210101879, Compound FAH-65)
Affinity DataIC50: 19nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796667BDBM796667(US20210101879, Compound FAH-152)
Affinity DataIC50: 20nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796650BDBM796650(US20210101879, Compound FAH-84)
Affinity DataIC50: 28nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796659BDBM796659(US20210101879, Compound FAH-110)
Affinity DataIC50: 47nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519501BDBM519501(US11142505, FAH-32 | US20210101879, Compound FAH-3...)
Affinity DataIC50: 70nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796660BDBM796660(US20210101879, Compound FAH-111)
Affinity DataIC50: 80nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796643BDBM796643(US20210101879, Compound FAH-69)
Affinity DataIC50: 110nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519506BDBM519506(US11142505, FAH-43 | US20210101879, Compound FAH-4...)
Affinity DataIC50: 140nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796644BDBM796644(US20210101879, Compound FAH-72)
Affinity DataIC50: 140nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796655BDBM796655(US20210101879, Compound FAH-99)
Affinity DataIC50: 150nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796668BDBM796668(US20210101879, Compound FAH-156)
Affinity DataIC50: 200nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796664BDBM796664(US20210101879, Compound FAH-135)
Affinity DataIC50: 210nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796647BDBM796647(US20210101879, Compound FAH-75)
Affinity DataIC50: 210nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796651BDBM796651(US20210101879, Compound FAH-85)
Affinity DataIC50: 220nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796634BDBM796634(US20210101879, Compound FAH-57)
Affinity DataIC50: 240nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796665BDBM796665(US20210101879, Compound FAH-136)
Affinity DataIC50: 250nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796661BDBM796661(US20210101879, Compound FAH-116)
Affinity DataIC50: 270nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796653BDBM796653(US20210101879, Compound FAH-87)
Affinity DataIC50: 300nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519507BDBM519507(US11142505, FAH-44 | US20210101879, Compound FAH-4...)
Affinity DataIC50: 300nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519475BDBM519475(US11142505, FAH #62 | US20210101879, Compound FAH-...)
Affinity DataIC50: 370nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796666BDBM796666(US20210101879, Compound FAH-137)
Affinity DataIC50: 460nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796648BDBM796648(US20210101879, Compound FAH-82)
Affinity DataIC50: 780nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796654BDBM796654(US20210101879, Compound FAH-88)
Affinity DataIC50: 840nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796645BDBM796645(US20210101879, Compound FAH-73)
Affinity DataIC50: 870nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519515BDBM519515(US11142505, FAH-63 | US20210101879, Compound FAH-6...)
Affinity DataIC50: 1.18E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796662BDBM796662(US20210101879, Compound FAH-117)
Affinity DataIC50: 1.37E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519471BDBM519471(US11142505, FAH #47 | US20210101879, Compound FAH-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519513BDBM519513(US11142505, FAH-59 | US20210101879, Compound FAH-5...)
Affinity DataIC50: 1.50E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519470BDBM519470(US11142505, FAH #46 | US20210101879, Compound FAH-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519473BDBM519473(US11142505, FAH #53 | US20210101879, Compound FAH-...)
Affinity DataIC50: 1.90E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519503BDBM519503(US11142505, FAH-37 | US20210101879, Compound FAH-3...)
Affinity DataIC50: 1.93E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796657BDBM796657(US20210101879, Compound FAH-106)
Affinity DataIC50: 2.18E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519505BDBM519505(US11142505, FAH-42 | US20210101879, Compound FAH-4...)
Affinity DataIC50: 2.30E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796656BDBM796656(US20210101879, Compound FAH-100)
Affinity DataIC50: 2.31E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796649BDBM796649(US20210101879, Compound FAH-83)
Affinity DataIC50: 2.91E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796638BDBM796638(US20210101879, Compound FAH-64)
Affinity DataIC50: 3.20E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 419594BDBM419594(US20210101879, Compound FAH-31)
Affinity DataIC50: 4.34E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519472BDBM519472(US11142505, FAH #48 | US20210101879, Compound FAH-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796658BDBM796658(US20210101879, Compound FAH-107)
Affinity DataIC50: 8.87E+3nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519465BDBM519465(US11142505, FAH #33 | US11142505, FAH-33 | US20210...)
Affinity DataIC50: 1.00E+4nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519467BDBM519467(US11142505, FAH #38 | US11142505, FAH-38 | US20210...)
Affinity DataIC50: 1.53E+4nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796642BDBM796642(US20210101879, Compound FAH-68)
Affinity DataIC50: 1.61E+4nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetBeta-secretase 1(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796641BDBM796641(US20210101879, Compound FAH-67)
Affinity DataIC50: 2.43E+4nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetCathepsin D(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796639BDBM796639(US20210101879, Compound FAH-65)
Affinity DataIC50: 4.71E+4nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetCathepsin D(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 796652BDBM796652(US20210101879, Compound FAH-86)
Affinity DataIC50: 5.00E+4nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent

TargetCathepsin D(Human)
University of California

US Patent
LigandChemical structure of BindingDB Monomer ID 519501BDBM519501(US11142505, FAH-32 | US20210101879, Compound FAH-3...)
Affinity DataIC50: 1.00E+5nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
9/8/2020
Entry Details
US Patent