Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 11434
TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195239BDBM50195239(CHEMBL3972563 | US10287258, Example 29 | US1066924...)
Affinity DataIC50: 2.40nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385058BDBM385058(US10669245, Example 18 | US11117874, Example 18 | ...)
Affinity DataIC50: 3.16nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195235BDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50: 4.47nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385076BDBM385076(US11680049, Example 36 | US20230278969, Example 36...)
Affinity DataIC50: 5.01nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385055BDBM385055(US10287258, Example 15 | (2S)-N-{(1S)-1-Cyano-2-[4...)
Affinity DataIC50: 5.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385077BDBM385077(US11680049, Example 37 | US20230278969, Example 37...)
Affinity DataIC50: 5.25nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 604854BDBM604854(US11667615, Example 10 | (2S)-N-{(1S)-1-Cyano-2-[4...)
Affinity DataIC50: 5.75nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385057BDBM385057((2S)-N-[(1S)-1-Cyano-2-{4-[3-(cyclopropylmethyl)-2...)
Affinity DataIC50: 6.31nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195248BDBM50195248(CHEMBL3891374 | US10287258, Example 27 | US1066924...)
Affinity DataIC50: 6.61nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 616202BDBM616202((2S)-N-[(1S)-1-Cyano-2-(4-13-[2-(dimethylamino)eth...)
Affinity DataIC50: 7.24nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385068BDBM385068(US11667615, Example 28 | (2S)-N-[(1S)-1-Cyano-2-{4...)
Affinity DataIC50: 8.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385061BDBM385061(US11117874, Example 21 | (2S)-N-[(1S)-1-Cyano-2-{4...)
Affinity DataIC50: 8.13nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385052BDBM385052(US10287258, Example 12 | US11117874, Example 12 | ...)
Affinity DataIC50: 10nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195240BDBM50195240(CHEMBL3960432 | US10287258, Example 3 | US10669245...)
Affinity DataIC50: 10.2nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385065BDBM385065(US10287258, Example 25 | US11667615, Example 25 | ...)
Affinity DataIC50: 10.7nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195238BDBM50195238(CHEMBL3962926 | US10287258, Example 20 | US1066924...)
Affinity DataIC50: 12.6nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385049BDBM385049(US10669245, Example 9 | US11117874, Example 9 | US...)
Affinity DataIC50: 12.9nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385066BDBM385066(US10287258, Example 26 | US11667615, Example 26 | ...)
Affinity DataIC50: 13.5nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195244BDBM50195244(CHEMBL3926554 | US10287258, Example 24 | US1066924...)
Affinity DataIC50: 13.8nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385059BDBM385059(US10669245, Example 19 | (2S)-N- [(1S)-1-Cyano-2-{...)
Affinity DataIC50: 14.5nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195245BDBM50195245(CHEMBL3972158 | US10287258, Example 5 | US10669245...)
Affinity DataIC50: 16.2nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195242BDBM50195242(CHEMBL3917575 | US10287258, Example 14 | US1066924...)
Affinity DataIC50: 16.6nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385062BDBM385062(US11667615, Example 22 | US11117874, Example 22 | ...)
Affinity DataIC50: 19.5nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385050BDBM385050((2S)-N-{(1S)-1-Cyano-2-[4-(3-ethyl-7-methyl-2-oxo-...)
Affinity DataIC50: 21.4nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385071BDBM385071(US11667615, Example 31 | US10669245, Example 31 | ...)
Affinity DataIC50: 21.4nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385075BDBM385075(US10287258, Example 35 | US10669245, Example 35 | ...)
Affinity DataIC50: 24.5nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195236BDBM50195236(CHEMBL3927609 | US10287258, Example 1 | US10669245...)
Affinity DataIC50: 35.5nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195255BDBM50195255(CHEMBL3945475 | US10287258, Example 6 | US10669245...)
Affinity DataIC50: 36.3nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385070BDBM385070(US10669245, Example 30 | (2S)-N-{(1S)-1-Cyano-2-[4...)
Affinity DataIC50: 37.2nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385072BDBM385072(US11117874, Example 32 | US11667615, Example 32 | ...)
Affinity DataIC50: 42.7nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195262BDBM50195262(CHEMBL3966946 | US11655221, Example 34 | US2023027...)
Affinity DataIC50: 60.3nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 50195263BDBM50195263(CHEMBL3942969 | US10287258, Example 33 | US1066924...)
Affinity DataIC50: 61.7nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385063BDBM385063((2S)-N-[(1S)-2-(4'-Carbamoy1-3'-fluorobiphenyl-4-y...)
Affinity DataIC50: 67.6nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385047BDBM385047(US11117874, Example 7 | (2S)-N-[(1S)-1-Cyano-2-(3'...)
Affinity DataIC50: 69.2nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385044BDBM385044(4′-[(2S)-2-Cyano-2-{[(2S)-1,4-oxazepan-2-ylc...)
Affinity DataIC50: 79.4nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385048BDBM385048(US11117874, Example 8 | US10287258, Example 8 | US...)
Affinity DataIC50: 87.1nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 385051BDBM385051(US11667615, Example 11 | (2S)-N-[(1S)-1-Cyano-2-{4...)
Affinity DataIC50: 89.1nMAssay Description:The activity of DPP1 was determined by measuring the enzymatic release of aminomethyl coumarin (AMC) from the peptide substrate (H-Gly-Arg-AMC), whic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2023
Entry Details
US Patent