Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 11614
TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576730BDBM50576730(CHEMBL4869200 | US20230348495, Example 9)
Affinity DataIC50: 0.700nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576728BDBM50576728(CHEMBL4849611 | US20230348495, Example 7)
Affinity DataIC50: 0.700nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633148BDBM633148(US20230348495, Example 1)
Affinity DataIC50: 0.800nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576729BDBM50576729(CHEMBL4876274 | US20230348495, Example 8)
Affinity DataIC50: 0.900nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576726BDBM50576726(CHEMBL4872714 | US20230348495, Example 3)
Affinity DataIC50: 1.20nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633208BDBM633208(US20230348495, Example 11)
Affinity DataIC50: 1.40nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576725BDBM50576725(CHEMBL4875572 | US20230348495, Example 2)
Affinity DataIC50: 1.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633194BDBM633194(US20230348495, Example 4)
Affinity DataIC50: 1.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633207BDBM633207(US20230348495, Example 10)
Affinity DataIC50: 1.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633226BDBM633226(US20230348495, Example 20)
Affinity DataIC50: 3nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633229BDBM633229(US20230348495, Example 23)
Affinity DataIC50: 3nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633238BDBM633238(US20230348495, Example 32)
Affinity DataIC50: 3.20nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576727BDBM50576727(CHEMBL4857517 | US20230348495, Example 6)
Affinity DataIC50: 3.20nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633234BDBM633234(US20230348495, Example 28)
Affinity DataIC50: 3.60nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633209BDBM633209(US20230348495, Example 12)
Affinity DataIC50: 4.40nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633218BDBM633218(US20230348495, Example 15)
Affinity DataIC50: 4.70nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576731BDBM50576731(CHEMBL4852554 | US20230348495, Example 18)
Affinity DataIC50: 5.10nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633210BDBM633210(US20230348495, Example 13)
Affinity DataIC50: 5.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633195BDBM633195(US20230348495, Example 5)
Affinity DataIC50: 6.20nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633225BDBM633225(US20230348495, Example 19)
Affinity DataIC50: 7.10nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633212BDBM633212(US20230348495, Example 14)
Affinity DataIC50: 8.90nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633243BDBM633243(US20230348495, Example 37)
Affinity DataIC50: 9.60nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576732BDBM50576732(CHEMBL4878409 | US20230348495, Example 21)
Affinity DataIC50: 9.70nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633220BDBM633220(US20230348495, Example 16)
Affinity DataIC50: 10.2nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633239BDBM633239(US20230348495, Example 33)
Affinity DataIC50: 11.3nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633236BDBM633236(US20230348495, Example 30)
Affinity DataIC50: 11.7nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633228BDBM633228(US20230348495, Example 22)
Affinity DataIC50: 13nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633241BDBM633241(US20230348495, Example 35)
Affinity DataIC50: 13.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633240BDBM633240(US20230348495, Example 34)
Affinity DataIC50: 14.1nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633222BDBM633222(US20230348495, Example 17)
Affinity DataIC50: 14.6nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633230BDBM633230(US20230348495, Example 24)
Affinity DataIC50: 17nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633237BDBM633237(US20230348495, Example 31)
Affinity DataIC50: 17.7nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 50576733BDBM50576733(CHEMBL4853619 | US20230348495, Example 27)
Affinity DataIC50: 18.5nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633232BDBM633232(US20230348495, Example 26)
Affinity DataIC50: 19.9nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633242BDBM633242(US20230348495, Example 36)
Affinity DataIC50: 27.4nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633235BDBM633235(US20230348495, Example 29)
Affinity DataIC50: 37.8nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Taiho Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 633231BDBM633231(US20230348495, Example 25)
Affinity DataIC50: 39.8nMAssay Description:For the measurement of the inhibitory activity of compounds on GDP-GTP exchange rate of recombinant KRAS G12D, BODIPY FL GDP-bound KRAS G12D protein ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2023
Entry Details
US Patent