Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 11644
TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636515BDBM636515(US20230365558, Compound 36)
Affinity DataIC50: 7nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636517BDBM636517(US20230365558, Compound 37)
Affinity DataIC50: 8nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636513BDBM636513(US20230365558, Compound 35)
Affinity DataIC50: 11nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636530BDBM636530(US20230365558, Compound 34)
Affinity DataIC50: 13nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636520BDBM636520(US20230365558, Compound 8)
Affinity DataIC50: 15nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636526BDBM636526(US20230365558, Compound 24)
Affinity DataIC50: 15nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636528BDBM636528(US20230365558, Compound 29)
Affinity DataIC50: 16nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636516BDBM636516(US20230365558, Compound 3)
Affinity DataIC50: 18nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636524BDBM636524(US20230365558, Compound 23)
Affinity DataIC50: 18nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636512BDBM636512(US20230365558, Compound 1)
Affinity DataIC50: 20nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636518BDBM636518(US20230365558, Compound 4)
Affinity DataIC50: 22nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636531BDBM636531(US20230365558, Compound 49b)
Affinity DataIC50: 26.2nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636519BDBM636519(US20230365558, Compound 39)
Affinity DataIC50: 34nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636521BDBM636521(US20230365558, Compound 40)
Affinity DataIC50: 34nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636529BDBM636529(US20230365558, Compound 48b)
Affinity DataIC50: 34.2nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636522BDBM636522(US20230365558, Compound 9)
Affinity DataIC50: 36nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636525BDBM636525(US20230365558, Compound 47)
Affinity DataIC50: 42nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636527BDBM636527(US20230365558, Compound 48a)
Affinity DataIC50: 46.2nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636523BDBM636523(US20230365558, Compound 46a)
Affinity DataIC50: 58nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent

TargetProtein arginine N-methyltransferase 5(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 636514BDBM636514(US20230365558, Compound 2)
Affinity DataIC50: 128nMAssay Description:Experimental objective: To test the inhibitory effect of compounds on PRMT5 enzyme activity. Experimental materials: PRMT5 enzyme. Experimental opera...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/12/2024
Entry Details
US Patent