Compile Data Set for Download or QSAR
Report error Found 100 Enz. Inhib. hit(s) with all data for entry = 11699
TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640844BDBM640844(N2-(2-ethoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640845BDBM640845(8-(1,5-dimethyl-1H-pyrazol-4-yl)-N-(2-methoxy-6-me...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640838BDBM640838(N-(2-ethoxy-6-methyl-5,6,7,8-tetrahydro-1,6-naphth...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640839BDBM640839(8-(2-methoxyphenyl)-N-(6-methyl-5,6,7,8-tetrahydro...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640850BDBM640850(8-benzyl-N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640851BDBM640851(3-((8-(1,5-dimethyl-1H-pyrazol-4-yl)quinazolin-2-y...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640849BDBM640849((R)-N8-(3,3-dimethylbut-2-yl)-N2-(2-ethoxy-6-methy...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640890BDBM640890(US20230399327, Example 104)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640891BDBM640891(US20230399327, Example 105)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640893BDBM640893(US20230399327, Example 107)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640886BDBM640886(US20230399327, Example 100)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640887BDBM640887(US20230399327, Example 101)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640888BDBM640888(US20230399327, Example 102)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640885BDBM640885(US20230399327, Example 103 | US20230399327, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640898BDBM640898((R)-2-((2-((6-methoxy-2-methyl-1,2,3,4 tetrahydroi...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640834BDBM640834(8-(6-chloropyridin-2-yl)-N-(2-methoxy-6-methyl-5,6...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640835BDBM640835(N2-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-naph...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640836BDBM640836((S)-N8-(3,3-dimethylbut-2-yl)-N2-(2-methoxy-6-meth...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640894BDBM640894(US20230399327, Example 108)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640895BDBM640895(US20230399327, Example 109)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640896BDBM640896(US20230399327, Example 110)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640897BDBM640897(US20230399327, Example 111)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640833BDBM640833(N8-isobutyl-N2-(2-methoxy-6-methyl-5,6,7,8-tetrahy...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640811BDBM640811(3-(2-((2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-n...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640875BDBM640875(US20230399327, Example 89)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640876BDBM640876(US20230399327, Example 90)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640818BDBM640818(8-(2-fluoro-6-methoxyphenyl)-N-(2-methoxy-6-methyl...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640820BDBM640820(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640821BDBM640821(1-(2-((2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-n...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640885BDBM640885(US20230399327, Example 103 | US20230399327, Exampl...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640815BDBM640815(1-(4-(2-((2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640879BDBM640879(US20230399327, Example 93)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640816BDBM640816(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640817BDBM640817(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640854BDBM640854(6-methyl-3-((8-(neopentylamino)pyrido[3,4-d]pyrimi...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640802BDBM640802(8-(2-fluorophenyl)-N-(2-methoxy-6-methyl-5,6,7,8-t...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640866BDBM640866(3-((8-(4,4-difluoropiperidin-1-yl)piperido[3,4-d]p...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640803BDBM640803(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640804BDBM640804(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640869BDBM640869(3-((8-(4,4-difluoropiperidin-1-yl)pyrido[3,4-d]pyr...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640799BDBM640799(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640863BDBM640863(3-((8-(cyclohex-1-en-1-yl)pyrido[3,4-d]pyrimidin-2...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640800BDBM640800(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640864BDBM640864((R)-6-methyl-3-((8-(2-methylpiperidin-1-yl)pyrido[...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640801BDBM640801(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640865BDBM640865(6-methyl-3-((8-(((1-methylcyclopropyl)methyl)amino...)
Affinity DataIC50: 0.100nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640840BDBM640840(N-(2,6-dimethyl-5,6,7,8-tetrahydro-1,6-naphthyridi...)
Affinity DataIC50: 0.150nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640822BDBM640822(N-(2-methoxy-6-methyl-5,6,7,8-tetrahydro-1,6-napht...)
Affinity DataIC50: 0.160nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640870BDBM640870(6-(2-hydroxyethyl)-1-methyl-3-((8-(piperidin-1-yl)...)
Affinity DataIC50: 0.160nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Adlai Nortye Biopharma Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 640880BDBM640880(US20230399327, Example 94)
Affinity DataIC50: 0.160nMAssay Description:The specific operation is as follows: configure the enzymatic reaction system buffer (10 mM MOPS, pH 7.2, 5 mM β-glycerol-phosphate, 10 mM MgCl2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2024
Entry Details
US Patent

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