Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 11872
TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656032(2-fluoro-1-[6-({4-methyl-1-[6-(difluoromethyl)pyri...)
Affinity DataKi:  0.900nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656030(1-[6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl...)
Affinity DataKi:  1.10nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656031(1-[6-({1-[6-(difluoromethyl)pyridin-3-yl]-4-methyl...)
Affinity DataKi:  1.60nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM655994(1-[6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazo...)
Affinity DataKi:  1.70nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656014(2-fluoro-1-(3-{[5-methyl-3-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  1.90nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656016(N-cyclopropyl-3-{[5-methyl-3-(6-methylpyridin-3-yl...)
Affinity DataKi:  2.20nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656009(1-(3-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazo...)
Affinity DataKi:  2.30nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM655997(2-methanesulfonyl-1-(6-{[5-methyl-3-(6-methylpyrid...)
Affinity DataKi:  3.5nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656015(2-methyl-1-(3-{[5-methyl-3-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  4.30nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656012(5-{4-[({7-cyclopropanecarbonyl-5H,6H,7H,8H-pyrido[...)
Affinity DataKi:  4.40nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656006((5R)-1-methyl-5-(6-{[5-methyl-3-(6-methylpyridin-3...)
Affinity DataKi:  5.70nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656013(1-(3-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazo...)
Affinity DataKi:  6nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM655998(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  6nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656019(2-fluoro-1-(6-{[4-methyl-1-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  6.60nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656008(1-ethyl-4-(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1...)
Affinity DataKi:  6.90nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656002(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  7.20nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656018(1-(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-...)
Affinity DataKi:  7.90nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656017(1-[3-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl...)
Affinity DataKi:  8.10nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656003(1-methyl-4-(6-{[5-methyl-3-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  8.30nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656005(1-methyl-5-(6-{[5-methyl-3-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  9nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656037(2-fluoro-1-(6-{[1-methyl-4-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  9.10nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656006((5R)-1-methyl-5-(6-{[5-methyl-3-(6-methylpyridin-3...)
Affinity DataKi:  9.40nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM655996(1-[6-({5-methyl-3-[6-(trifluoromethyl)pyridin-3-yl...)
Affinity DataKi:  9.70nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656011(2-methyl-5-[5-methyl-4-({[7-(oxane-4-carbonyl)-5H,...)
Affinity DataKi:  10nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656000(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  10nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656004(4-(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazo...)
Affinity DataKi:  11nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656010(4-(3-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazo...)
Affinity DataKi:  13nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656026(2-fluoro-1-[6-({4-methyl-1-[6-(trifluoromethyl)pyr...)
Affinity DataKi:  15nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM655999(4-(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazo...)
Affinity DataKi:  16nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656001(6-{[5-methyl-3-(6-methylpyridin-3-yl)-1,2-oxazol-4...)
Affinity DataKi:  17nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656022(1-(6-{[4-methyl-1-(6-methylpyridin-3-yl)-1H-1,2,3-...)
Affinity DataKi:  20nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656023(2-cyclopropanecarbonyl-6-{[4-methyl-1-(6-methylpyr...)
Affinity DataKi:  22nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656033(1-(6-{[1-methyl-4-(6-methylpyridin-3-yl)-1H-1,2,3-...)
Affinity DataKi:  22nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656024(1-[6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl...)
Affinity DataKi:  25nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656020(2-methyl-1-(6-{[4-methyl-1-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  30nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656028(2-cyclopropanecarbonyl-6-({4-methyl-1-[6-(trifluor...)
Affinity DataKi:  31nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656025(1-[6-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl...)
Affinity DataKi:  33nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656034(1-(6-{[1-methyl-4-(6-methylpyridin-3-yl)-1H-1,2,3-...)
Affinity DataKi:  33nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656038(1-(6-{[1-methyl-4-(6-methylpyridin-3-yl)-1H-1,2,3-...)
Affinity DataKi:  37.2nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM655995(tert-butyl 6-{[5-methyl-3-(6-methylpyridin-3-yl)-1...)
Affinity DataKi:  38nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656035(2-methyl-1-(6-{[1-methyl-4-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  43nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656027(2-methyl-1-[6-({4-methyl-1-[6-(trifluoromethyl)pyr...)
Affinity DataKi:  44nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656021(3-methyl-1-(6-{[4-methyl-1-(6-methylpyridin-3-yl)-...)
Affinity DataKi:  48nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656036(2-cyclopropanecarbonyl-6-{[1-methyl-4-(6-methylpyr...)
Affinity DataKi:  52nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent

TargetGamma-aminobutyric acid receptor subunit alpha-5(Human)
Richter Gedeon

US Patent
LigandPNGBDBM656029(1-[3-({4-methyl-1-[6-(trifluoromethyl)pyridin-3-yl...)
Affinity DataKi:  99.1nMAssay Description:Receptor binding assays were performed in 96-well format in deep-well plates. For each 96-well plate one ampule of membrane homogenate was thawed and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
US Patent