Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 11893
TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657972BDBM657972(US20240083888, Compound 38A)
Affinity DataIC50: 1.30nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657958BDBM657958(4-Amino-N-(1-cyano-2-(2,8-difluoro-6H-benzo[c]chro...)
Affinity DataIC50: 2.70nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657960BDBM657960(4-Amino-N-(1-cyano-2-(8-cyano-6H-benzo[c]chromen-3...)
Affinity DataIC50: 3.10nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657956BDBM657956(US20240083888, Compound 22 | 4-Amino-N-(1-cyano-2-...)
Affinity DataIC50: 3.20nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657975BDBM657975((S)-4-Amino-N-(1-cyano-2-(9-fluoro-6-methyl-5-oxo-...)
Affinity DataIC50: 3.70nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657949BDBM657949((S)-N-((S)-1-Cyano-2-(8-cyano-2-fluoro-6H-benzo[c]...)
Affinity DataIC50: 5.31nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657952BDBM657952((S)-4-Amino-N-(1-cyano-2-(8,9-difluoro-6H-benzo[c]...)
Affinity DataIC50: 5.70nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657977BDBM657977((S)-4-Amino-N-(1-cyano-2-(7-fluorodibenzo[b,d]fura...)
Affinity DataIC50: 5.70nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657967BDBM657967(4-Amino-N-(1-cyano-2-(9-(pyrrolidin-3-yl)-6H-benzo...)
Affinity DataIC50: 6.20nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657942BDBM657942(4-Amino-N-(1-cyano-2-(9,10-dihydrophenanthren-2-yl...)
Affinity DataIC50: 6.80nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657970BDBM657970(4-Amino-N-(1-cyano-2-(9-fluoro-6,7-dihydrodibenzo[...)
Affinity DataIC50: 7.10nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 50195235BDBM50195235(CHEMBL3900409 | US10287258, Example 2 | US10669245...)
Affinity DataIC50: 7.69nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657961BDBM657961((2S,3aS,6aS)-N-((S)-1-Cyano-2-(8-cyano-2-fluoro-6H...)
Affinity DataIC50: 8.90nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657964BDBM657964((S)-N-((S)-1-Cyano-2-(2-fluoro-8-(methylsulfonyl)-...)
Affinity DataIC50: 10nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657955BDBM657955((S)-N-((S)-1-Cyano-2-(2,8-difluoro-6H-benzo[c]chro...)
Affinity DataIC50: 11nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657965BDBM657965((S)-N-((S)-1-Cyano-2-(9-cyano-2-fluoro-6H-benzo[c]...)
Affinity DataIC50: 13nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657971BDBM657971(4-Amino-N-(1-cyano-2-(9-fluoro-5,7-dihydrodibenzo[...)
Affinity DataIC50: 14nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657956BDBM657956(US20240083888, Compound 22 | 4-Amino-N-(1-cyano-2-...)
Affinity DataIC50: 14.5nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657969BDBM657969((2S)-N-(2-(8-(Azetidin-1-ylsulfonyl)-2-fluoro-6H-b...)
Affinity DataIC50: 15nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657947BDBM657947((2S)-N-(1-Cyano-2-(2,8-difluoro-6H-benzo[c]chromen...)
Affinity DataIC50: 16nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657993BDBM657993((S)-1-Amino-N-(1-cyano-2-(2-(4-fluorophenyl)-3-oxo...)
Affinity DataIC50: 17nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657963BDBM657963((2S)-N-(1-Cyano-2-(2-fluoro-8-(methylsulfonyl)-6H-...)
Affinity DataIC50: 17.1nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657985BDBM657985((S)-4-Amino-N-(1-cyano-2-(3-oxo-2-phenylisoindolin...)
Affinity DataIC50: 19nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657962BDBM657962((S)-N-((S)-1-Cyano-2-(8-cyano-2-fluoro-6,6-dimethy...)
Affinity DataIC50: 23nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657978BDBM657978((2S)-N-(1-Cyano-2-(2-fluoro-9-(methylsulfonyl)-6H-...)
Affinity DataIC50: 26nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657989BDBM657989((S)-4-Amino-N-(1-cyano-2-(2-(4-fluorophenyl)isoind...)
Affinity DataIC50: 28nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657983BDBM657983((S)-4-Amino-N-(1-cyano-2-(2-(3-methyl-2-oxo-2,3-di...)
Affinity DataIC50: 29nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657982BDBM657982((S)-4-Amino-N-(1-cyano-2-(2-(3-cyanophenyl)-1-oxoi...)
Affinity DataIC50: 29nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657976BDBM657976((S)-N-((S)-1-Cyano-2-(9-cyano-2-fluoro-6-methyl-5-...)
Affinity DataIC50: 30.5nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657953BDBM657953(US20240083888, Compound 18 | (2S)-N-(1-Cyano-2-(3-...)
Affinity DataIC50: 32nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657948BDBM657948((2S)-N-(1-Cyano-2-(8-cyano-6H-benzo[c]chromen-3-yl...)
Affinity DataIC50: 37nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657991BDBM657991((S)-4-Amino-N-(1-cyano-2-(2-(4-fluorobenzoyl)-1,2,...)
Affinity DataIC50: 37nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657986BDBM657986((S)-4-Amino-N-(1-cyano-2-(2-methyl-1,2,3,4-tetrahy...)
Affinity DataIC50: 39nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657979BDBM657979((S)-4-Amino-N-(1-cyano-2-(4-(4-fluorophenyl)-5-oxo...)
Affinity DataIC50: 39nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657936BDBM657936((S)-4-Amino-N-(1-cyano-2-(1-oxo-2-phenylisoindolin...)
Affinity DataIC50: 42nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657974BDBM657974(4-Amino-N-(1-cyano-2-(3-fluoro-6,7-dihydrodibenzo[...)
Affinity DataIC50: 46nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657992BDBM657992((S)-4-Amino-N-(1-cyano-2-(2-(4-fluorophenyl)-1,2,3...)
Affinity DataIC50: 48nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657953BDBM657953(US20240083888, Compound 18 | (2S)-N-(1-Cyano-2-(3-...)
Affinity DataIC50: 49nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657981BDBM657981((S)-4-Amino-N-(1-cyano-2-(2-(4-cyanobenzoyl)isoind...)
Affinity DataIC50: 54nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657939BDBM657939(4-Amino-N-(1-cyano-2-(5,6,7,8-tetrahydronaphthalen...)
Affinity DataIC50: 54nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657941BDBM657941(4-Amino-N-(1-cyano-2-(2,3-dihydro-1H-inden-5-yl)et...)
Affinity DataIC50: 56nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657984BDBM657984((S)-4-Amino-N-(1-cyano-2-(1-oxo-2-phenyl-1,2,3,4-t...)
Affinity DataIC50: 57nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657943BDBM657943((S)-N-((S)-1-Cyano-2-(9,10-dihydrophenanthren-2-yl...)
Affinity DataIC50: 60nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657980BDBM657980((S)-4-Amino-N-(1-cyano-2-(2-(4-cyanophenyl)-1-oxoi...)
Affinity DataIC50: 72nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657946BDBM657946((2S)—N-(1-Cyano-2-(8-fluoro-6H-benzo[c]chrome...)
Affinity DataIC50: 74nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657945BDBM657945((S)-4-Amino-N-(2-(chroman-7-yl)-1-cyanoethyl)tetra...)
Affinity DataIC50: 74nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657973BDBM657973(US20240083888, Compound 38B)
Affinity DataIC50: 76nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657966BDBM657966((2S)—N-(1-Cyano-2-(3-cyano-9-fluoro-5H-chrome...)
Affinity DataIC50: 85nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657951BDBM657951((S)-N-((S)-1-Cyano-2-(8,9-difluoro-6H-benzo[c]chro...)
Affinity DataIC50: 91nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandChemical structure of BindingDB Monomer ID 657987BDBM657987((S)-4-Amino-N-(1-cyano-2-(isochroman-7-yl)ethyl)te...)
Affinity DataIC50: 138nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
US Patent

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