Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 11963
TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665692BDBM665692(US20240116912, Example 71 | 3-(6-((2R,4R)-4-((5-cy...)
Affinity DataEC50:  2.10nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665639BDBM665639(US20240116912, Example 18 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  2.90nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665687BDBM665687(US20240116912, Example 66 | 3-(6-((1R,3r,5S)-3-((5...)
Affinity DataEC50:  3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665644BDBM665644(US20240116912, Example 23 | 3-(4-((2R,4R)-4-((5-cy...)
Affinity DataEC50:  3.10nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665671BDBM665671(US20240116912, Example 50 | 3-(4-((1R,F,5S)-3-((5-...)
Affinity DataEC50:  3.20nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665634BDBM665634(US20240116912, Example 13 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  3.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665624BDBM665624(US20240116912, Example 3 | 3-(4-(4-((5-cyclopropyl...)
Affinity DataEC50:  3.60nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665668BDBM665668(US20240116912, Example 47 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  3.70nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665627BDBM665627(US20240116912, Example 6 | 3-(6-(4-((5-cyclopropyl...)
Affinity DataEC50:  4.40nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665693BDBM665693(US20240116912, Example 72 | 3-(6-((2R,4R)-4-((3-(2...)
Affinity DataEC50:  4.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665635BDBM665635(US20240116912, Example 14 | 3-(2-chloro-4-(4-((5-c...)
Affinity DataEC50:  8.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665674BDBM665674(US20240116912, Example 53 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  9nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665646BDBM665646(US20240116912, Example 25 | 2-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  9.10nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665631BDBM665631(US20240116912, Example 10 | 6-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  9.10nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665690BDBM665690(US20240116912, Example 69 | 5-(6-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  9.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665664BDBM665664(US20240116912, Example 43 | 6-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  11.2nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665670BDBM665670(US20240116912, Example 49 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  11.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665653BDBM665653(US20240116912, Example 32 | 3-(4-((3S,4R)-4-((5-cy...)
Affinity DataEC50:  12.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665688BDBM665688(US20240116912, Example 67 | 6-(4-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  12.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665660BDBM665660(US20240116912, Example 39 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  16.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665680BDBM665680(US20240116912, Example 59 | 5-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  17.9nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665657BDBM665657(US20240116912, Example 36 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  18.8nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665665BDBM665665(US20240116912, Example 44 | 3-(4-(4-((3-(2-chlorop...)
Affinity DataEC50:  21.3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665632BDBM665632(US20240116912, Example 11 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  21.9nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665686BDBM665686(US20240116912, Example 65 | 5-(4-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  22.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665637BDBM665637(US20240116912, Example 16 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  24nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665689BDBM665689(US20240116912, Example 68 | 5-(6-((1R,3R,5S)-3-((5...)
Affinity DataEC50:  26.4nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665629BDBM665629(US20240116912, Example 8 | 3-(5-(4-((5-cyclopropyl...)
Affinity DataEC50:  28.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665659BDBM665659(US20240116912, Example 38 | 3-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  28.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665626BDBM665626(US20240116912, Example 5 | 3-(2-(4-((5-cyclopropyl...)
Affinity DataEC50:  31nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665675BDBM665675(US20240116912, Example 54 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  37.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665669BDBM665669(US20240116912, Example 48 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  41.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665677BDBM665677(US20240116912, Example 56 | 3-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  43.1nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665656BDBM665656(US20240116912, Example 35 | 3-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  43.5nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665652BDBM665652(US20240116912, Example 31 | 3-(4-((3R,4S)-4-((5-cy...)
Affinity DataEC50:  45nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665694BDBM665694(US20240116912, Example 73 | 3-(6-((2R,4R)-4-((5-cy...)
Affinity DataEC50:  47.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665658BDBM665658(US20240116912, Example 37 | 5-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  49.4nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665662BDBM665662(US20240116912, Example 41 | 6-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  58.4nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665643BDBM665643(US20240116912, Example 22 | 3-(4-((2S,4S)-4-((5-cy...)
Affinity DataEC50:  63.3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665685BDBM665685(US20240116912, Example 64 | 3-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  70nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665633BDBM665633(US20240116912, Example 12 | 5-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  73.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665667BDBM665667(US20240116912, Example 46 | 6-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  74.6nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665661BDBM665661(US20240116912, Example 40 | 5-(5-(4-((5-cyclopropy...)
Affinity DataEC50:  76nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665642BDBM665642(US20240116912, Example 21 | 3-(4-((2R,4S)-4-((5-cy...)
Affinity DataEC50:  79.3nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665678BDBM665678(US20240116912, Example 57 | 6-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  84.7nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665681BDBM665681(US20240116912, Example 60 | 5-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  104nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665628BDBM665628(US20240116912, Example 7 | 3-(3-(4-((5-cyclopropyl...)
Affinity DataEC50:  105nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665695BDBM665695(US20240116912, Example 74 | 3-(6-(4-((5-cyclopropy...)
Affinity DataEC50:  107nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665647BDBM665647(US20240116912, Example 26 | 3-(4-(4-((5-cyclopropy...)
Affinity DataEC50:  111nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

TargetRNA-binding protein FXR1 [244-476](Human)
Terns Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 665641BDBM665641(US20240116912, Example 20 | 3-(4-((2S,4R)-4-((5-cy...)
Affinity DataEC50:  114nMAssay Description:A cell free coactivator recruitment assay was developed for FXR, to measure the functional potency of novel FXR compounds. In this assay, novel FXR c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2024
Entry Details
US Patent

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