Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 12002
TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669519(US20240132463, Compound 1 | N-(2-(2,6-dioxopiperid...)
Affinity DataIC50: 2nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669522(US20240132463, Compound 7 | 3-chloro-N-(2-(2,6-dio...)
Affinity DataIC50: 13nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669521(US20240132463, Compound 5 | 3-chloro-N-(2-(2,6-dio...)
Affinity DataIC50: 38nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669520(US20240132463, Compound 2 | N-(2-(2,6-dioxopiperid...)
Affinity DataIC50: 54nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent

TargetProtein cereblon(Human)
St. Jude Children'S Research Hospital

US Patent
LigandPNGBDBM669523(US20240132463, Compound 20 | N-(2-(2,6-dioxopiperi...)
Affinity DataIC50: 72nMAssay Description:In this competitive fluorescent polarization assay Cy5 conjugated lenalidomide analog (Cy5-O-Len)13 was used as a fluorescent probe. 6×His-CRBN-DDB1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/16/2024
Entry Details
US Patent