Compile Data Set for Download or QSAR
Report error Found 1791 Enz. Inhib. hit(s) with all data for entry = 12029
TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671244BDBM671244((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.300nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671279BDBM671279((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)-sec-b...)
Affinity DataIC50: 0.300nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671102BDBM671102((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.330nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672599BDBM672599((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.330nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671846BDBM671846((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.330nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672675BDBM672675((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.330nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671343BDBM671343((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)-sec-b...)
Affinity DataIC50: 0.350nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671722BDBM671722((3S,9S,18S,21S,25S,28S,34S)-28-cyclohexyl-9-(cyclo...)
Affinity DataIC50: 0.350nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671446BDBM671446((3S,9S,18S,21S,25S,28S,34S)-28-cyclohexyl-9-(cyclo...)
Affinity DataIC50: 0.350nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672081BDBM672081((3S,9S,18S,21S,25S,28S,34S,36R)-3-[2-[3-chloro-4-(...)
Affinity DataIC50: 0.360nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671849BDBM671849((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.370nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671243BDBM671243((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.370nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672486BDBM672486((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.370nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672410BDBM672410((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.380nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671322BDBM671322((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.380nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672608BDBM672608((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.380nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672016BDBM672016((3S,9S,18S,21S,25S,28S,34S)-28-cyclohexyl-9-(cyclo...)
Affinity DataIC50: 0.390nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672532BDBM672532((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.400nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672447BDBM672447((6S,9S,13S,16S,22S,25S,31S,34S)-25-[2-[3-chloro-4-...)
Affinity DataIC50: 0.410nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672584BDBM672584((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.410nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672485BDBM672485((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.410nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672774BDBM672774(US20240148821, Compound 2117 | (3S,9S,18S,21S,25S,...)
Affinity DataIC50: 0.410nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672093BDBM672093((3S,9S,18S,21S,25S,28S,34S)-28-cyclohexyl-9-(cyclo...)
Affinity DataIC50: 0.420nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672735BDBM672735(5-(2-((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)...)
Affinity DataIC50: 0.420nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671879BDBM671879((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.420nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672402BDBM672402((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.420nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672569BDBM672569((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.430nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671241BDBM671241((3S,6S,9S,13S,16S,22S,25S,31S,34S)-25-[2-[3-chloro...)
Affinity DataIC50: 0.430nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672667BDBM672667((3S,9S,18S,21S,25S,28S,34S,36R)-3-[2-[3-chloro-4-(...)
Affinity DataIC50: 0.430nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671147BDBM671147((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8-((S)-sec-b...)
Affinity DataIC50: 0.430nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672027BDBM672027((3S,9S,18S,21S,25S,28S,34S,36R)-3-[2-[3-chloro-4-(...)
Affinity DataIC50: 0.440nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671829BDBM671829((3S,6S,9S,13S,16S,22S,25S,31S,34S)-25-[2-[3-chloro...)
Affinity DataIC50: 0.440nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671862BDBM671862((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.440nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671648BDBM671648((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.440nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672503BDBM672503((3S,9S,18S,21S,25S,28S,34S,36R)-3-[2-[3-chloro-4-(...)
Affinity DataIC50: 0.450nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672643BDBM672643((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.450nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671282BDBM671282((3S,9S,18S,21S,25S,28S,34S)-3-[2-(4-chlorophenyl)e...)
Affinity DataIC50: 0.450nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672778BDBM672778(US20240148821, Compound 2122 | (3S,9S,18S,21S,25S,...)
Affinity DataIC50: 0.460nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671773BDBM671773((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671101BDBM671101((3S,9S,18S,21S,25S,28S,34S)-28-cyclohexyl-9-(cyclo...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671311BDBM671311((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671995BDBM671995((3S,9S,18S,21S,25S,28S,34S)-9-(cyclohexylmethyl)-2...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671765BDBM671765((5S,8S,11S,15S,18S,23aS,29S,35S,37aS)-8,18-di((S)-...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672052BDBM672052((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672656BDBM672656((3S,9S,18S,21S,25S,28S,34S,36R)-3-[2-[3-chloro-4-(...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672547BDBM672547((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672770BDBM672770(US20240148821, Compound 2113 | (3S,9S,18S,21S,25S,...)
Affinity DataIC50: 0.470nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672574BDBM672574((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.480nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 672137BDBM672137((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.480nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

TargetGTPase KRas (G12D) and Son of Sevenless Homolog 1 (SOS)(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 671481BDBM671481((3S,9S,18S,21S,25S,28S,34S)-3-[2-[3-chloro-4-(trif...)
Affinity DataIC50: 0.480nMAssay Description:Protein-protein interaction inhibition (PPI) between Kras and SOS1 was measured by energy transfer from nickel-conjugated donor beads to streptavidin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2024
Entry Details
US Patent

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