Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 12149
LigandChemical structure of BindingDB Monomer ID 682742BDBM682742(US20240208953, Example 17A)
Affinity DataIC50: 200nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682741BDBM682741(US20240208953, Example 16B)
Affinity DataIC50: 200nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682740BDBM682740(US20240208953, Example 16A)
Affinity DataIC50: 400nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682754BDBM682754(US20240208953, Example 42B)
Affinity DataIC50: 800nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682743BDBM682743(US20240208953, Example 18B)
Affinity DataIC50: 1.20E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682745BDBM682745(US20240208953, Example 24C | 6-((R)-2-((3aR,5R,6aS...)
Affinity DataIC50: 1.20E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682739BDBM682739(US20240208953, Example 14B)
Affinity DataIC50: 1.30E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682738BDBM682738(US20240208953, Example 10A)
Affinity DataIC50: 2.10E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682753BDBM682753(US20240208953, Example 42A)
Affinity DataIC50: 2.20E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682746BDBM682746(US20240208953, Example 28A | 6-((R)-1-hydroxy-2-((...)
Affinity DataIC50: 2.40E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682737BDBM682737(US20240208953, Example 8A)
Affinity DataIC50: 2.80E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682744BDBM682744(US20240208953, Example 21)
Affinity DataIC50: 3.60E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682749BDBM682749(US20240208953, Example 31B | 8-fluoro-6-((S)-1-hyd...)
Affinity DataIC50: 3.90E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682751BDBM682751(US20240208953, Example 33B)
Affinity DataIC50: 4.90E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682752BDBM682752(US20240208953, Example 36A)
Affinity DataIC50: 5.50E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682734BDBM682734(US20240208953, Example 5D)
Affinity DataIC50: 5.90E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682733BDBM682733(US20240208953, Example 5C)
Affinity DataIC50: 6.00E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682748BDBM682748(US20240208953, Example 31A | 8-fluoro-6-((R)-1-hyd...)
Affinity DataIC50: 7.30E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682731BDBM682731(US20240208953, Example 1B | 6-((S)-1-hydroxy-2-((3...)
Affinity DataIC50: 7.60E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682746BDBM682746(US20240208953, Example 28A | 6-((R)-1-hydroxy-2-((...)
Affinity DataIC50: 8.20E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682732BDBM682732(US20240208953, Example 4B | 6-((S)-2-((3aS,4S,5S,6...)
Affinity DataIC50: 9.20E+3nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682730BDBM682730(US20240208953, Example 1A | 6-((R)-1-hydroxy-2-((3...)
Affinity DataIC50: 1.07E+4nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682747BDBM682747(US20240208953, Example 29B | 8-fluoro-6-((S)-2-((3...)
Affinity DataIC50: 1.25E+4nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682735BDBM682735(US20240208953, Example 6C | 8-fluoro-6-((R)-2-((3a...)
Affinity DataIC50: 1.33E+4nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682736BDBM682736(US20240208953, Example 7B)
Affinity DataIC50: 1.52E+4nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 682755BDBM682755(US20240208953, Example 44B | (3aS,4S,5S,6aR)-5-(2-...)
Affinity DataIC50: 1.57E+4nMAssay Description:hERG currents were recorded using the Qpatch automated patch clamp systems (Sophion Bioscience Inc., North Brunswick, NJ) in the whole (single) cell ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent