Compile Data Set for Download or QSAR
Report error Found 113 Enz. Inhib. hit(s) with all data for entry = 12152
TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682868BDBM682868(US20240208970, Compound 50 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  28nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682869BDBM682869(US20240208970, Compound 51 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  29nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682872BDBM682872(US20240208970, Compound 56 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  31nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682875BDBM682875(US20240208970, Compound 62 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  36nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682816BDBM682816(US20240208970, Compound 15 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  38nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682871BDBM682871(US20240208970, Compound 53 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  42nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682837BDBM682837(US20240208970, Compound 44 | US20240208970, Compou...)
Affinity DataIC50: 57nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682835BDBM682835(US20240208970, Compound 42 | 2-(3-chlorothiophen-2...)
Affinity DataIC50: 59nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682829BDBM682829(US20240208970, Compound 36 | 2-(2-chloro-6- fluoro...)
Affinity DataIC50: 64nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682841BDBM682841(US20240208970, Compound 49 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 64nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682842BDBM682842(US20240208970, Compound 54 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 66nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682890BDBM682890(US20240208970, Compound 95 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 69nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682831BDBM682831(US20240208970, Compound 38 | US20240208970, Compou...)
Affinity DataIC50: 71nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682817BDBM682817(US20240208970, Compound 16 | US20240208970, Compou...)
Affinity DataIC50: 79nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682816BDBM682816(US20240208970, Compound 15 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 80nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682837BDBM682837(US20240208970, Compound 44 | US20240208970, Compou...)
Affinity DataIC50: 81nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682833BDBM682833(US20240208970, Compound 40 | 2-(2-chlorothiophen-3...)
Affinity DataIC50: 81nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682827BDBM682827(US20240208970, Compound 34 | US20240208970, Compou...)
Affinity DataIC50: 82nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682863BDBM682863(US20240208970, Compound 24 | 2-(7-(isoquinolin-4-y...)
Affinity DataIC50: 86nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682898BDBM682898(US20240208970, Compound 63 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  87nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682898BDBM682898(US20240208970, Compound 63 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  89nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682825BDBM682825(US20240208970, Compound 32 | 2-(2-chloro-4- fluoro...)
Affinity DataIC50: 95nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682826BDBM682826(US20240208970, Compound 33 | 2-(2-chloro-4- fluoro...)
Affinity DataIC50: 99nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682868BDBM682868(US20240208970, Compound 50 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 105nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682884BDBM682884(US20240208970, Compound 89 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 105nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682882BDBM682882(US20240208970, Compound 87 | 2-(2-chloro-4,5- difl...)
Affinity DataIC50: 115nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682817BDBM682817(US20240208970, Compound 16 | US20240208970, Compou...)
Affinity DataIC50: 127nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682870BDBM682870(US20240208970, Compound 52 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  134nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682817BDBM682817(US20240208970, Compound 16 | US20240208970, Compou...)
Affinity DataIC50: 140nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682869BDBM682869(US20240208970, Compound 51 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 141nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682802BDBM682802(US20240208970, Compound 1 | US20240208970, Compoun...)
Affinity DataKd:  141nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682872BDBM682872(US20240208970, Compound 56 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 145nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682823BDBM682823(US20240208970, Compound 30 | 2-(2-chloro-3- fluoro...)
Affinity DataIC50: 150nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682888BDBM682888(US20240208970, Compound 93 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 157nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682822BDBM682822(US20240208970, Compound 29 | US20240208970, Compou...)
Affinity DataIC50: 165nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682805BDBM682805(US20240208970, Compound 4 | 7-(isoquinolin-4-yl)-2...)
Affinity DataKd:  168nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682835BDBM682835(US20240208970, Compound 42 | 2-(3-chlorothiophen-2...)
Affinity DataIC50: 185nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682843BDBM682843(US20240208970, Compound 55 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 187nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682861BDBM682861(US20240208970, Compound 22 | 7-(isoquinolin-4-yl)-...)
Affinity DataIC50: 197nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682875BDBM682875(US20240208970, Compound 62 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 201nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682829BDBM682829(US20240208970, Compound 36 | 2-(2-chloro-6- fluoro...)
Affinity DataIC50: 205nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682897BDBM682897(US20240208970, Compound 61 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  214nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682885BDBM682885(US20240208970, Compound 90 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 223nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682878BDBM682878(US20240208970, Compound 83 | 2-(2-chloro-4-fluorop...)
Affinity DataIC50: 241nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682873BDBM682873(US20240208970, Compound 59 | 2-(2-chlorophenyl)-7-...)
Affinity DataKd:  250nMAssay Description:The SPR experiments were performed using a Biacore S200 instrument and CM5 biosensor chips (Cytiva, Uppsala, Sweden) at 25 C. Streptavidin (Sigma) wa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682871BDBM682871(US20240208970, Compound 53 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 253nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682883BDBM682883(US20240208970, Compound 88 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 253nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682802BDBM682802(US20240208970, Compound 1 | US20240208970, Compoun...)
Affinity DataIC50: 260nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682892BDBM682892(US20240208970, Compound 97 | 2-(2-chlorophenyl)-7-...)
Affinity DataIC50: 287nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Individual

US Patent
LigandChemical structure of BindingDB Monomer ID 682822BDBM682822(US20240208970, Compound 29 | US20240208970, Compou...)
Affinity DataIC50: 291nMAssay Description:It was performed in 20 mM Tris, 50 mM NaCl and 0.1 mM EDTA (Merck KGaA, Darmstadt, Germany), pH 7.5 at room temperature. Compounds were transferred w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2024
Entry Details
US Patent

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