Compile Data Set for Download or QSAR
Report error Found 490 Enz. Inhib. hit(s) with all data for entry = 12177
TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662513BDBM662513(N-(4-(2-(4- chlorophenyl)but-3- yn-2-yl)thiazol-2-...)
Affinity DataIC50: 3.70nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662250BDBM662250((S)-1-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol...)
Affinity DataIC50: 4nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662520BDBM662520((S)-N-(4-(2-(4- chlorophenyl)but-3- yn-2-yl)thiazo...)
Affinity DataIC50: 5nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662263BDBM662263(US20240109853, Compound A299 | US20240109853, Comp...)
Affinity DataIC50: 5.40nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662517BDBM662517(2,6-difluoro-N-(4-(2- (4- fluorophenyl)propan- 2-y...)
Affinity DataIC50: 6nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662324BDBM662324(N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol-2-y...)
Affinity DataIC50: 7nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662274BDBM662274(1-((2-(3- aminopyrrolidin-1- yl)pyrimidin-5- yl)me...)
Affinity DataIC50: 7nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662552BDBM662552(2,6-difluoro-N-[4-[1- methyl-1-(p- tolyl)prop-2- y...)
Affinity DataIC50: 7nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662254BDBM662254((S)-N-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol...)
Affinity DataIC50: 7nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662521BDBM662521(N-(4-(2-(4- chlorophenyl)but-3- yn-2-yl)thiazol-2-...)
Affinity DataIC50: 7nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662165BDBM662165(1-((2-(3- aminopyrrolidin-1- yl)pyrimidin-5- yl)me...)
Affinity DataIC50: 8nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662260BDBM662260((S)-1-(4-(2-(4- methoxyphenyl)but-3- yn-2-yl)thiaz...)
Affinity DataIC50: 8nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662257BDBM662257((S)-1-(2-hydroxyethyl)- 3-(4-(2-(4- methoxyphenyl)...)
Affinity DataIC50: 8nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662147BDBM662147(5-((3-(4-(2-(4- methoxyphenyl)propan- 2-yl)thiazol...)
Affinity DataIC50: 8nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662536BDBM662536((S)-N-(4-(2-(4- chlorophenyl)-1- methoxypropan-2- ...)
Affinity DataIC50: 8nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662095BDBM662095(4-((3-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2...)
Affinity DataIC50: 8nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662180BDBM662180(1-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2-yl)...)
Affinity DataIC50: 9nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662291BDBM662291(1-(4-(4-aminopiperidin- 1-yl)benzyl)-3-(4-(2-(4- b...)
Affinity DataIC50: 9nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662300BDBM662300(1-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2-yl)...)
Affinity DataIC50: 9nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662247BDBM662247((S)-1-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol...)
Affinity DataIC50: 10nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662519BDBM662519((R)-N-(4-(2-(4- chlorophenyl)but-3- yn-2-yl)thiazo...)
Affinity DataIC50: 10nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662515BDBM662515(N-(4-(1-(4- chlorophenyl)ethyl)thi- azol-2-yl)-2,6...)
Affinity DataIC50: 11nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662470BDBM662470(N-(4-(2-(4-chlorophenyl)but- 3-yn-2-yl)thiazol-2-y...)
Affinity DataIC50: 12nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662186BDBM662186(1-((2-(4-aminopiperidin- 1-yl)pyrimidin-5- yl)meth...)
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662323BDBM662323(N-(4-(1-(4- bromophenyl)cyclopent- yl)thiazol-2-yl...)
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662526BDBM662526(US20240109853, Compound C014 | N-(4-(2-(4- bromoph...)
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662349BDBM662349(1-(4-(2-(4- chlorophenyl)but-3-yn- 2-yl)thiazol-2-...)
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662111BDBM662111(1-(4-(2-(4- chlorophenyl)but-3-yn- 2-yl)thiazol-2-...)
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662175BDBM662175(1-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2-yl)...)
Affinity DataIC50: 13nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662567BDBM662567(US20240109853, Compound D004 | N-(4-(2-(4-chloroph...)
Affinity DataIC50: 14nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662280BDBM662280(1-(4-(4-aminopiperidin- 1-yl)benzyl)-3-(4-(1-(4- b...)
Affinity DataIC50: 15nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662129BDBM662129(4-((3-(4-(2-(4- methoxyphenyl)propan- 2-yl)thiazol...)
Affinity DataIC50: 15nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662528BDBM662528(US20240109853, Compound C016 | N-(4-(2-(4- chlorop...)
Affinity DataIC50: 16nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662547BDBM662547(US20240109853, Compound C036 | 2,6-difluoro-N-[4-[...)
Affinity DataIC50: 16nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662258BDBM662258(1-(4-(2-(4- methoxyphenyl)but-3- yn-2-yl)thiazol-2...)
Affinity DataIC50: 16nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662173BDBM662173(1-(4-(2-(4- methoxyphenyl)propan- 2-yl)thiazol-2-y...)
Affinity DataIC50: 16nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662332BDBM662332(S)-N-(4-(2-(4- chlorophenyl)but-3-yn- 2-yl)thiazol...)
Affinity DataIC50: 16nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662567BDBM662567(US20240109853, Compound D004 | N-(4-(2-(4-chloroph...)
Affinity DataIC50: 16nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662168BDBM662168(1-((2-((2- aminoethyl)amino)pyri- midin-5-yl)methy...)
Affinity DataIC50: 17nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662251BDBM662251((R)-1-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol...)
Affinity DataIC50: 17nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662549BDBM662549(N-(4-(2-(4-chloro-3- fluorophenyl)but-3- yn-2-yl)t...)
Affinity DataIC50: 17nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685067BDBM685067(N-(4-(2-(4-chlorophenyl)but- 3-yn-2-yl)thiazol-2- ...)
Affinity DataIC50: 18nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662523BDBM662523((S)-N-(4-(2-(4- chlorophenyl)but-3- yn-2-yl)thiazo...)
Affinity DataIC50: 18nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 684782BDBM684782(1-(4-((2- aminoethyl)amino)-3- fluorobenzyl)-3-(4-...)
Affinity DataIC50: 18nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662202BDBM662202(5-((3-(4-(2-(4- methoxyphenyl)propan- 2-yl)thiazol...)
Affinity DataIC50: 19nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662325BDBM662325(1-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol-2-y...)
Affinity DataIC50: 19nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662546BDBM662546(2,6-difluoro-N-(4-(2- (4-fluorophenyl)but-3- yn-2-...)
Affinity DataIC50: 19nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 684770BDBM684770(1-((6-(3- aminopyrrolidin-1- yl)pyridin-3- yl)meth...)
Affinity DataIC50: 19nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662326BDBM662326(1-(4-(2-(4- bromophenyl)but-3-yn- 2-yl)thiazol-2-y...)
Affinity DataIC50: 20nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetAlpha-protein kinase 1(Human)
Shanghai Yao Yuan Biotechnology Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 662179BDBM662179(1-(4-(2-(4- bromophenyl)propan-2- yl)thiazol-2-yl)...)
Affinity DataIC50: 20nMAssay Description:In brief, dose-response studies were performed with HEK293 cells cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented 10% fetal bovine se...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

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