Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 12183
TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684691BDBM684691(US20240228490, Example 3 | 3-Ethyl-7-((4-(8-(methy...)
Affinity DataIC50: 0.400nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684706BDBM684706(5-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.600nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684706BDBM684706(5-(1-((7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-...)
Affinity DataIC50: 0.600nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684690BDBM684690(US20240228490, Example 2 | 5-(1-((7-Ethyl-6-oxo-5,...)
Affinity DataIC50: 0.760nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684711BDBM684711(US20240228490, Example 59 | N-(1-Cyanocyclopropyl)...)
Affinity DataIC50: 0.800nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684701BDBM684701(US20240228490, Example 36 | US20240228490, Example...)
Affinity DataIC50: 0.800nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 595739BDBM595739(US11591331, Example 64 | US20240228490, Example 45)
Affinity DataIC50: 0.800nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684710BDBM684710(US20240228490, Example 58 | N-(Cyanomethyl)-1̸...)
Affinity DataIC50: 0.900nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684717BDBM684717(US20240228490, Example 81 | 1′-((7-Ethyl-6-o...)
Affinity DataIC50: 0.900nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684700BDBM684700(US20240228490, Example 33 | 4-(1-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 0.910nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 595701BDBM595701(US11591331, Example 8 | US20240228490, Example 1 |...)
Affinity DataIC50: 0.930nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684707BDBM684707(US20240228490, Example 53 | 7-((4-(1,5-Dimethyl-1H...)
Affinity DataIC50: 0.960nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684696BDBM684696(US20240228490, Example 29 | N-Cyclopropyl-1′...)
Affinity DataIC50: 0.980nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684701BDBM684701(US20240228490, Example 36 | US20240228490, Example...)
Affinity DataIC50: 1nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684699BDBM684699(US20240228490, Example 32 | (R)-1′-((7-Ethyl...)
Affinity DataIC50: 1nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684698BDBM684698(US20240228490, Example 31 | (S)-1′-((7-Ethyl...)
Affinity DataIC50: 1nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684708BDBM684708(US20240228490, Example 56 | 2-Chloro-1′-((7-...)
Affinity DataIC50: 1.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684704BDBM684704(US20240228490, Example 42 | 1′-((5-Cyano-3-e...)
Affinity DataIC50: 1.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684697BDBM684697(US20240228490, Example 30 | 1′-((7-Ethyl-6-o...)
Affinity DataIC50: 1.40nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684719BDBM684719(US20240228490, Example 83 | 1′-((7-Ethyl-6-o...)
Affinity DataIC50: 1.40nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684701BDBM684701(US20240228490, Example 36 | US20240228490, Example...)
Affinity DataIC50: 1.60nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684695BDBM684695(US20240228490, Example 24 | 3-Ethyl-7-((4-(2-methy...)
Affinity DataIC50: 1.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684713BDBM684713(US20240228490, Example 66 | 4-(1-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 1.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684727BDBM684727(US20240228490, Example 93 | 1′-(1-(7-Ethyl-6...)
Affinity DataIC50: 2.10nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684714BDBM684714(US20240228490, Example 67 | 4-(1-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 2.10nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684712BDBM684712(US20240228490, Example 65 | 3-Chloro-4-(1-((7-ethy...)
Affinity DataIC50: 2.20nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684725BDBM684725(US20240228490, Example 90 | 1′-((3-Ethyl-2-o...)
Affinity DataIC50: 2.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684720BDBM684720(US20240228490, Example 84 | N-Methyl-1′-((6-...)
Affinity DataIC50: 2.70nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684709BDBM684709(US20240228490, Example 57 | N-Cyano-1′-((7-e...)
Affinity DataIC50: 2.80nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684692BDBM684692(US20240228490, Example 6 | 3-Ethyl-7-((4-(2-methyl...)
Affinity DataIC50: 2.90nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684726BDBM684726(US20240228490, Example 91 | 1′-((3-Ethyl-2,4...)
Affinity DataIC50: 3nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684694BDBM684694(US20240228490, Example 23 | 7-((4-(1H-Pyrrolo[2,3-...)
Affinity DataIC50: 3.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684715BDBM684715(US20240228490, Example 79 | 5-(4-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 3.30nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684721BDBM684721(US20240228490, Example 85 | 2-Chloro-1′-((3-...)
Affinity DataIC50: 3.5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684693BDBM684693(US20240228490, Example 17 | 3-Ethyl-7-((4-(1-oxois...)
Affinity DataIC50: 4.5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684723BDBM684723(US20240228490, Example 87 | 2-Chloro-1′-((2-...)
Affinity DataIC50: 4.90nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684724BDBM684724(US20240228490, Example 88 | 1′-((2-Ethyl-3-o...)
Affinity DataIC50: 5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684716BDBM684716(US20240228490, Example 80 | 6-(4-((7-Ethyl-6-oxo-5...)
Affinity DataIC50: 5nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent

TargetPoly [ADP-ribose] polymerase 1(Human)
Shanghai Hansoh Biomedical

US Patent
LigandChemical structure of BindingDB Monomer ID 684722BDBM684722(US20240228490, Example 86 | 1′-((3-Ethyl-2-o...)
Affinity DataIC50: 5.10nMAssay Description:1. Experimental ObjectiveThe experimental objective of this Test Example is to determine the inhibitory activity of the compounds on PARP1 enzyme.2. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/22/2024
Entry Details
US Patent