Compile Data Set for Download or QSAR
Report error Found 122 Enz. Inhib. hit(s) with all data for entry = 12197
TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685694BDBM685694(US20240239813, Compound 34a)
Affinity DataIC50: 3.10nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685724BDBM685724(US20240239813, Compound 49a)
Affinity DataIC50: 4.05nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685684BDBM685684(US20240239813, Compound 29a)
Affinity DataIC50: 4.30nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685662BDBM685662(US20240239813, Compound 18a)
Affinity DataIC50: 4.5nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685666BDBM685666(US20240239813, Compound 20a)
Affinity DataIC50: 4.70nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685610BDBM685610(US20240239813, Compound 68)
Affinity DataIC50: 6.30nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685726BDBM685726(US20240239813, Compound 50a)
Affinity DataIC50: 6.76nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685668BDBM685668(US20240239813, Compound 21a)
Affinity DataIC50: 6.80nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685646BDBM685646(US20240239813, Compound 10a)
Affinity DataIC50: 6.90nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685644BDBM685644(US20240239813, Compound 9a)
Affinity DataIC50: 7.90nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685692BDBM685692(US20240239813, Compound 33a)
Affinity DataIC50: 10.3nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685616BDBM685616(US20240239813, Compound 73)
Affinity DataIC50: 10.7nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685650BDBM685650(US20240239813, Compound 12a)
Affinity DataIC50: 12.1nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685680BDBM685680(US20240239813, Compound 27a)
Affinity DataIC50: 12.7nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685652BDBM685652(US20240239813, Compound 13a)
Affinity DataIC50: 13.2nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685678BDBM685678(US20240239813, Compound 26a)
Affinity DataIC50: 13.3nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685708BDBM685708(US20240239813, Compound 41a)
Affinity DataIC50: 14.2nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685664BDBM685664(US20240239813, Compound 19a)
Affinity DataIC50: 16.1nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685630BDBM685630(US20240239813, Compound 2a)
Affinity DataIC50: 18.8nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685656BDBM685656(US20240239813, Compound 15a)
Affinity DataIC50: 19.6nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685672BDBM685672(US20240239813, Compound 23a)
Affinity DataIC50: 31.2nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685686BDBM685686(US20240239813, Compound 30a)
Affinity DataIC50: 41.6nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 50614266BDBM50614266(CHEMBL5279240 | US20240239813, Compound 25)
Affinity DataIC50: 43.6nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685612BDBM685612(US20240239813, Compound 70)
Affinity DataIC50: 67.4nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685701BDBM685701(US20240239813, Compound 50)
Affinity DataIC50: 71nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685611BDBM685611(US20240239813, Compound 3)
Affinity DataIC50: 102nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685700BDBM685700(US20240239813, Compound 37a)
Affinity DataIC50: 121nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685620BDBM685620(US20240239813, Compound 96)
Affinity DataIC50: 128nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685632BDBM685632(US20240239813, Compound 3a)
Affinity DataIC50: 141nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685682BDBM685682(US20240239813, Compound 28a)
Affinity DataIC50: 159nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685677BDBM685677(US20240239813, Compound 38)
Affinity DataIC50: 163nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685609BDBM685609(US20240239813, Compound 2)
Affinity DataIC50: 185nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685714BDBM685714(US20240239813, Compound 44a)
Affinity DataIC50: 234nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685607BDBM685607(US20240239813, Compound 1)
Affinity DataIC50: 261nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685626BDBM685626(US20240239813, Compound 117)
Affinity DataIC50: 373nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685658BDBM685658(US20240239813, Compound 16a)
Affinity DataIC50: 385nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685608BDBM685608(US20240239813, Compound 67)
Affinity DataIC50: 415nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685618BDBM685618(US20240239813, Compound 92)
Affinity DataIC50: 416nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685706BDBM685706(US20240239813, Compound 40a)
Affinity DataIC50: 424nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685690BDBM685690(US20240239813, Compound 32a)
Affinity DataIC50: 481nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685715BDBM685715(US20240239813, Compound 57)
Affinity DataIC50: 510nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685688BDBM685688(US20240239813, Compound 31a)
Affinity DataIC50: 518nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685712BDBM685712(US20240239813, Compound 43a)
Affinity DataIC50: 557nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685676BDBM685676(US20240239813, Compound 25a)
Affinity DataIC50: 639nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685636BDBM685636(US20240239813, Compound 5a)
Affinity DataIC50: 652nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685718BDBM685718(US20240239813, Compound 46a)
Affinity DataIC50: 684nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685628BDBM685628(US20240239813, Compound 1a)
Affinity DataIC50: 752nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685621BDBM685621(US20240239813, Compound 10)
Affinity DataIC50: 881nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685627BDBM685627(US20240239813, Compound 13)
Affinity DataIC50: 979nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Risen (Suzhou) Pharma Tech Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 685629BDBM685629(US20240239813, Compound 14)
Affinity DataIC50: 1.00E+3nMAssay Description:The ability of a test compound to bind to KRASG12D was measured by using an HTRF KRASG12D GTP Binding Kit (Cisbio, 63ADK000CB27PEG). 100×His-tagged H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2024
Entry Details
US Patent

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