Compile Data Set for Download or QSAR
Report error Found 200 Enz. Inhib. hit(s) with all data for entry = 12214
TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688031BDBM688031(US20240247015, Example 144)
Affinity DataIC50: 1.97nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688082BDBM688082(US20240247015, Example 196)
Affinity DataIC50: 2.38nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687955BDBM687955(US20240247015, Example 66 | US20240247015, Example...)
Affinity DataIC50: 2.86nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688067BDBM688067(US20240247015, Example 181)
Affinity DataIC50: 2.95nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688065BDBM688065(US20240247015, Example 179)
Affinity DataIC50: 3.68nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688092BDBM688092(US20240247015, Example 206)
Affinity DataIC50: 3.77nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688071BDBM688071(US20240247015, Example 185)
Affinity DataIC50: 3.86nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688060BDBM688060(US20240247015, Example 174)
Affinity DataIC50: 3.89nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688088BDBM688088(US20240247015, Example 202)
Affinity DataIC50: 3.89nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688068BDBM688068(US20240247015, Example 182)
Affinity DataIC50: 3.95nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688086BDBM688086(US20240247015, Example 200)
Affinity DataIC50: 3.95nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688024BDBM688024(US20240247015, Example 137)
Affinity DataIC50: 4.04nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688079BDBM688079(US20240247015, Example 193)
Affinity DataIC50: 4.10nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688032BDBM688032(US20240247015, Example 145)
Affinity DataIC50: 4.35nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688051BDBM688051(US20240247015, Example 165)
Affinity DataIC50: 4.37nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688034BDBM688034(US20240247015, Example 147)
Affinity DataIC50: 4.51nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688066BDBM688066(US20240247015, Example 180)
Affinity DataIC50: 4.60nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688084BDBM688084(US20240247015, Example 198)
Affinity DataIC50: 4.61nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688085BDBM688085(US20240247015, Example 199)
Affinity DataIC50: 4.61nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688072BDBM688072(US20240247015, Example 186)
Affinity DataIC50: 4.71nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688036BDBM688036(US20240247015, Example 150)
Affinity DataIC50: 4.76nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688049BDBM688049(US20240247015, Example 163)
Affinity DataIC50: 4.77nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688058BDBM688058(US20240247015, Example 172)
Affinity DataIC50: 4.78nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688052BDBM688052(US20240247015, Example 166)
Affinity DataIC50: 4.83nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687931BDBM687931(US20240247015, Example 42 | 1-acetyl-4-[4-({(1R)-1...)
Affinity DataIC50: 4.87nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687988BDBM687988(US20240247015, Example 100)
Affinity DataIC50: 4.89nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688063BDBM688063(US20240247015, Example 177)
Affinity DataIC50: 5.01nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688043BDBM688043(US20240247015, Example 157)
Affinity DataIC50: 5.04nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688026BDBM688026(US20240247015, Example 139)
Affinity DataIC50: 5.40nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688059BDBM688059(US20240247015, Example 173)
Affinity DataIC50: 5.62nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688069BDBM688069(US20240247015, Example 184 | US20240247015, Exampl...)
Affinity DataIC50: 5.62nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688089BDBM688089(US20240247015, Example 203)
Affinity DataIC50: 5.65nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688087BDBM688087(US20240247015, Example 201)
Affinity DataIC50: 5.81nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687968BDBM687968(US20240247015, Example 81 | US20240247015, Example...)
Affinity DataIC50: 5.88nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688076BDBM688076(US20240247015, Example 190)
Affinity DataIC50: 5.90nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688090BDBM688090(US20240247015, Example 204)
Affinity DataIC50: 5.96nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688025BDBM688025(US20240247015, Example 138)
Affinity DataIC50: 6.01nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687954BDBM687954(US20240247015, Example 89 | US20240247015, Example...)
Affinity DataIC50: 6.06nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687935BDBM687935(US20240247015, Example 46 | 2-{3-[(1R)-1-{[6-(1-ac...)
Affinity DataIC50: 6.10nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688040BDBM688040(US20240247015, Example 154)
Affinity DataIC50: 6.15nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687899BDBM687899(US20240247015, Example 7 | 1-acetyl-4-[2-methyl-4-...)
Affinity DataIC50: 6.24nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688029BDBM688029(US20240247015, Example 142)
Affinity DataIC50: 6.30nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687947BDBM687947(US20240247015, Example 58)
Affinity DataIC50: 6.33nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688074BDBM688074(US20240247015, Example 188)
Affinity DataIC50: 6.34nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 687920BDBM687920(US20240247015, Example 31 | 4-[2-methyl-4-({(1R)-1...)
Affinity DataIC50: 6.37nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688081BDBM688081(US20240247015, Example 195)
Affinity DataIC50: 6.56nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688057BDBM688057(US20240247015, Example 171)
Affinity DataIC50: 6.76nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688062BDBM688062(US20240247015, Example 176)
Affinity DataIC50: 6.82nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688093BDBM688093(US20240247015, Example 207)
Affinity DataIC50: 6.84nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

TargetSon of sevenless homolog 1/GTPase KRas [G12C](Human)
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 688050BDBM688050(US20240247015, Example 164)
Affinity DataIC50: 7.01nMAssay Description:The assay buffer containes 5 mM HEPES pH 7.4 (Applichem), 150 mM NaCl (Sigma), 10 mM EDTA (Promega), 1 mM DTT (Thermofisher), 0.05% BSA Fraction V, p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2024
Entry Details
US Patent

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