Compile Data Set for Download or QSAR
Report error Found 1004 Enz. Inhib. hit(s) with all data for entry = 12278
TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692721BDBM692721(2-(7-((2S,5R)-5-ethyl-2-methyl-4-(1-(quinoxalin-6-...)
Affinity DataIC50: 1nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692696BDBM692696(US20240270751, Compound A74a)
Affinity DataIC50: 2.20nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693064BDBM693064(US20240270751, Compound A360b)
Affinity DataIC50: 2.70nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692676BDBM692676(2-(7-((2S,5R)-2,5-diethyl-4-(1- (isoquinolin-3-yl)...)
Affinity DataIC50: 2.80nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692695BDBM692695(2-(7-((2S,5R)-2,5-diethyl-4-(1-(5- fluoropyridin-2...)
Affinity DataIC50: 3.80nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692634BDBM692634(7-((2S,5R)-2,5-diethyl-4-(4- (trifluoromethoxy)ben...)
Affinity DataIC50: 4.30nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692712BDBM692712(2-(7-((2S,5R)-2,5-diethyl-4-(1- phenylethyl)pipera...)
Affinity DataIC50: 4.30nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692632BDBM692632(US20240270751, Compound A25 | 7-((2S,5R)-2,5-dieth...)
Affinity DataIC50: 4.30nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693065BDBM693065(2-(7-((2S,5R)-2,5-diethyl-4-(1-(5- (trifluorometho...)
Affinity DataIC50: 5.10nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692771BDBM692771(2-(7-((2S,5R)-4-(1-(2,4- difluorophenyl)ethyl)-2,5...)
Affinity DataIC50: 5.90nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693051BDBM693051(2-(7-((2S,5R)-4-(1-(3,3-dimethyl-2,3-dihydrofuro[3...)
Affinity DataIC50: 6nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692635BDBM692635(US20240270751, Compound A28 | US20240270751, Compo...)
Affinity DataIC50: 6.70nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693017BDBM693017(2-(7-((2S,5R)-4-(1-(3H-spiro[benzo[b][1,4]dioxine-...)
Affinity DataIC50: 7nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692763BDBM692763(2-(7-((2S,5R)-4-(1-(2,3-dihydrobenzo[b][1,4]dioxin...)
Affinity DataIC50: 7.20nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692676BDBM692676(2-(7-((2S,5R)-2,5-diethyl-4-(1- (isoquinolin-3-yl)...)
Affinity DataIC50: 7.30nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692636BDBM692636(US20240270751, Compound A28a)
Affinity DataIC50: 7.60nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692801BDBM692801(US20240270751, Compound A155b)
Affinity DataIC50: 7.60nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692635BDBM692635(US20240270751, Compound A28 | US20240270751, Compo...)
Affinity DataIC50: 7.80nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692671BDBM692671(2-(7-((2S,5R)-2,5-diethyl-4-((4- fluoro-2-methoxyp...)
Affinity DataIC50: 7.80nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693043BDBM693043(US20240270751, Compound A347b)
Affinity DataIC50: 8nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692722BDBM692722(US20240270751, Compound A97a)
Affinity DataIC50: 8.60nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692679BDBM692679(2-(7-((2S,5R)-2,5-diethyl-4-(1- (quinolin-7-yl)eth...)
Affinity DataIC50: 8.60nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692771BDBM692771(2-(7-((2S,5R)-4-(1-(2,4- difluorophenyl)ethyl)-2,5...)
Affinity DataIC50: 8.90nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693045BDBM693045(US20240270751, Compound A348b)
Affinity DataIC50: 9nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692673BDBM692673(2-(7-((2S,5R)-2,5-diethyl-4-(1- (quinoxalin-2-yl)e...)
Affinity DataIC50: 9nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692662BDBM692662(US20240270751, Compound A46d)
Affinity DataIC50: 9nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692700BDBM692700(2-(7-((2S,5R)-2,5-diethyl-4-(4- (trifluoromethoxy)...)
Affinity DataIC50: 9.20nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692665BDBM692665(2-(7-((2S,5R)-2,5-diethyl-4-(1-(quinoxalin-6-yl)et...)
Affinity DataIC50: 9.30nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692685BDBM692685(2-(7-((2S,5R)-2,5-diethyl-4-(1-(4- fluorophenyl)et...)
Affinity DataIC50: 10nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692758BDBM692758(2-(7-((2S,5R)-2,5-diethyl-4-(1-(4- (trifluorometho...)
Affinity DataIC50: 10.5nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693060BDBM693060(US20240270751, Compound A357b)
Affinity DataIC50: 12nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692683BDBM692683(2-(7-((2S,5R)-2,5-diethyl-4-(1-(3-methylquinoxalin...)
Affinity DataIC50: 12nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692713BDBM692713(2-(7-((2S,5R)-2,5-diethyl-4-(1- (pyridin-2-yl)ethy...)
Affinity DataIC50: 13nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692822BDBM692822(US20240270751, Compound A172b)
Affinity DataIC50: 14nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693012BDBM693012(2-(cyanomethyl)-7-((2S,5R)-2,5-dimethyl-4-((S)-1-(...)
Affinity DataIC50: 15nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692693BDBM692693(US20240270751, Compound A72b)
Affinity DataIC50: 15nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692725BDBM692725(US20240270751, Compound A98a)
Affinity DataIC50: 15nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692752BDBM692752(2-(7-((2S,5R)-2,5-diethyl-4-(1-(1-ethyl-5-(trifluo...)
Affinity DataIC50: 15nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692769BDBM692769(2-(7-((2S,5R)-2,5-diethyl-4-(1- (pyrimidin-2-yl)et...)
Affinity DataIC50: 15nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692833BDBM692833(2-(7-((2S,5R)-4-(1-(6-(difluoromethoxy)pyridin-3-y...)
Affinity DataIC50: 15nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692678BDBM692678(2-(7-((2S,5R)-2,5-diethyl-4-(1- (quinolin-6-yl)eth...)
Affinity DataIC50: 17nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692975BDBM692975(US20240270751, Compound A286b)
Affinity DataIC50: 17nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692802BDBM692802(2-(cyanomethyl)-7-((2S,5R)-5-ethyl-2-methyl-4-(1-(...)
Affinity DataIC50: 18nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693021BDBM693021(2-(7-((2S,5R)-2,5-diethyl-4-(1-(4- fluoro-2-(1- me...)
Affinity DataIC50: 19nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692993BDBM692993(2-(3,3-difluoroallyl)-7-((2S,5R)-2,5-dimethyl-4-((...)
Affinity DataIC50: 19nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692660BDBM692660(US20240270751, Compound A46b)
Affinity DataIC50: 21nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692954BDBM692954(US20240270751, Compound A269d)
Affinity DataIC50: 21nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase zeta(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 693011BDBM693011(2-(7-((2S,5R)-2,5-dimethyl-4-((S)-1-(3-methylquino...)
Affinity DataIC50: 21nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692709BDBM692709(2-(7-((2S,5R)-2,5-diethyl-4-(1- (pyridin-4-yl)ethy...)
Affinity DataIC50: 22nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

TargetDiacylglycerol kinase alpha(Human)
Beigene

US Patent
LigandChemical structure of BindingDB Monomer ID 692673BDBM692673(2-(7-((2S,5R)-2,5-diethyl-4-(1- (quinoxalin-2-yl)e...)
Affinity DataIC50: 22nMAssay Description:The inhibition activities testing for the compound disclosed herein were carried out at room temperature in assay buffer containing 50 mM HEPES, 10 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/3/2024
Entry Details
US Patent

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