Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 12265
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691426BDBM691426(US20240279174, Compound JH-LPH-104)
Affinity DataIC50: 0.230nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691422BDBM691422(US20240279174, Compound JH-LPH-96)
Affinity DataIC50: 2nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691420BDBM691420(US20240279174, Compound JH-LPH-92)
Affinity DataIC50: 5nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691408BDBM691408(US20240279174, Compound JH-LPH-50)
Affinity DataIC50: 8nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691423BDBM691423(US20240279174, Compound JH-LPH-97)
Affinity DataIC50: 8nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691425BDBM691425(US20240279174, Compound JH-LPH-99)
Affinity DataIC50: 11nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691409BDBM691409(US20240279174, Compound JH-LPH-65)
Affinity DataIC50: 13nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691405BDBM691405(US20240279174, Compound JH-LPH-45)
Affinity DataIC50: 17nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691424BDBM691424(US20240279174, Compound JH-LPH-98)
Affinity DataIC50: 24nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691421BDBM691421(US20240279174, Compound JH-LPH-93)
Affinity DataIC50: 32nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691413BDBM691413(US20240279174, Compound JH-LPH-79)
Affinity DataIC50: 37nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691412BDBM691412(US20240279174, Compound JH-LPH-73)
Affinity DataIC50: 37nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691406BDBM691406(US20240279174, Compound JH-LPH-48)
Affinity DataIC50: 49nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691411BDBM691411(US20240279174, Compound JH-LPH-70)
Affinity DataIC50: 62nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691404BDBM691404(US20240279174, Compound JH-LPH-41)
Affinity DataIC50: 73nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691410BDBM691410(US20240279174, Compound JH-LPH-69)
Affinity DataIC50: 79nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691415BDBM691415(US20240279174, Compound JH-LPH-86)
Affinity DataIC50: 85nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691403BDBM691403(US20240279174, Compound JH-LPH-33 | US20240417387,...)
Affinity DataIC50: 104nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691419BDBM691419(US20240279174, Compound JH-LPH-91)
Affinity DataIC50: 105nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691418BDBM691418(US20240279174, Compound JH-LPH-90)
Affinity DataIC50: 111nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691402BDBM691402(US20240279174, Compound JH-LPH-28)
Affinity DataIC50: 139nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691407BDBM691407(US20240279174, Compound JH-LPH-49)
Affinity DataIC50: 152nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691401BDBM691401(US20240279174, Compound AZ1 | US20240279174, Compo...)
Affinity DataIC50: 361nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691414BDBM691414(US20240279174, Compound JH-LPH-80)
Affinity DataIC50: 431nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691417BDBM691417(US20240279174, Compound JH-LPH-89)
Affinity DataIC50: 2.44E+3nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetUDP-2,3-diacylglucosamine hydrolase()
Duke University

US Patent
LigandChemical structure of BindingDB Monomer ID 691416BDBM691416(US20240279174, Compound JH-LPH-88)
Affinity DataIC50: 3.20E+3nMAssay Description:Briefly, two reaction mixtures were prepared. Mixture 1 contains 20 mM Tris-HCl (pH 8.0), 0.5 mg/mL BSA, 0.02% Triton X-100, 1 mM MnCl2, 1 mM DTT, 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent