Compile Data Set for Download or QSAR
Report error Found 472 Enz. Inhib. hit(s) with all data for entry = 12267
TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691911BDBM691911(US20240279215, Compound 372 | US20240279215, Compo...)
Affinity DataEC50:  240nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691544BDBM691544(US20240279215, Compound 5 | 4-(hydroxymethyl)benzy...)
Affinity DataEC50:  290nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691489BDBM691489(US20240279215, Compound 3 | pyridin-4-ylmethyl (R)...)
Affinity DataEC50:  310nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691551BDBM691551(US20240279215, Compound 12 | 4-chlorobenzyl (S)-(4...)
Affinity DataEC50:  340nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691427BDBM691427(US20240279215, Compound 1 | 4-methoxybenzyl (R)-(4...)
Affinity DataEC50:  440nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691545BDBM691545(US20240279215, Compound 6 | oxazol-5-ylmethyl (R)-...)
Affinity DataEC50:  550nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691558BDBM691558(US20240279215, Compound 19 | 4-chlorobenzyl (4- ((...)
Affinity DataEC50:  590nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691702BDBM691702(US20240279215, Compound 163 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  680nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691573BDBM691573(US20240279215, Compound 34 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  820nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691589BDBM691589(US20240279215, Compound 50 | 4-chlorobenzyl (4-((N...)
Affinity DataEC50:  890nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691615BDBM691615(US20240279215, Compound 76 | 4-chlorobenzyl (S)-(4...)
Affinity DataEC50:  890nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691556BDBM691556(US20240279215, Compound 17 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  900nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691488BDBM691488(US20240279215, Compound 2 | 4-carbamoylbenzyl (R)-...)
Affinity DataEC50:  960nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691575BDBM691575(US20240279215, Compound 36 | 4-chlorobenzyl (4-((3...)
Affinity DataEC50:  1.00E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691572BDBM691572(US20240279215, Compound 33 | 4-chlorobenzyl (4- ((...)
Affinity DataEC50:  1.01E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691963BDBM691963(US20240279215, Compound 424 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  1.13E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691639BDBM691639(US20240279215, Compound 100 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  1.22E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691577BDBM691577(US20240279215, Compound 38 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  1.22E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691697BDBM691697(US20240279215, Compound 158 | 4-chlorobenzyl (4-((...)
Affinity DataEC50:  1.27E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691596BDBM691596(US20240279215, Compound 57 | 4-chlorobenzyl (S)-(4...)
Affinity DataEC50:  1.29E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691613BDBM691613(US20240279215, Compound 74 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  1.42E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691637BDBM691637(US20240279215, Compound 98 | methyl 4-(4-((((4- ch...)
Affinity DataEC50:  1.49E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691568BDBM691568(US20240279215, Compound 29 | 4-chlorobenzyl (4-((4...)
Affinity DataEC50:  1.51E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691703BDBM691703(US20240279215, Compound 164 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  1.60E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691616BDBM691616(US20240279215, Compound 77 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  1.67E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691597BDBM691597(US20240279215, Compound 58 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  1.73E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691626BDBM691626(US20240279215, Compound 87 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  1.75E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691612BDBM691612(US20240279215, Compound 73 | 4-chlorobenzyl (4-((4...)
Affinity DataEC50:  1.76E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691929BDBM691929(US20240279215, Compound 390 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  1.80E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691594BDBM691594(US20240279215, Compound 55 | 4-chlorobenzyl (4-((3...)
Affinity DataEC50:  1.82E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691584BDBM691584(US20240279215, Compound 45 | 4-chlorobenzyl (4-((1...)
Affinity DataEC50:  1.88E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691563BDBM691563(US20240279215, Compound 24 | 4-chlorobenzyl (4-((4...)
Affinity DataEC50:  1.88E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691641BDBM691641(US20240279215, Compound 102 | 4-chlorobenzyl (4-((...)
Affinity DataEC50:  1.89E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691778BDBM691778(US20240279215, Compound 239 | 4-chlorobenzyl (4-((...)
Affinity DataEC50:  1.89E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691599BDBM691599(US20240279215, Compound 60 | 4-chlorobenzyl (S)-(4...)
Affinity DataEC50:  1.91E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691644BDBM691644(US20240279215, Compound 105 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  1.94E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691560BDBM691560(US20240279215, Compound 21 | 4-chlorobenzyl (4-((6...)
Affinity DataEC50:  2.00E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691588BDBM691588(US20240279215, Compound 49 | 4-chlorobenzyl (4-((N...)
Affinity DataEC50:  2.02E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691915BDBM691915(US20240279215, Compound 376 | oxazol-5-ylmethyl (R...)
Affinity DataEC50:  2.02E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691724BDBM691724(US20240279215, Compound 185 | 4-chlorobenzyl (4-((...)
Affinity DataEC50:  2.04E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691973BDBM691973(US20240279215, Compound 434 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  2.11E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691739BDBM691739(US20240279215, Compound 200 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  2.12E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691760BDBM691760(US20240279215, Compound 221 | 4-chlorobenzyl (4-(2...)
Affinity DataEC50:  2.16E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691554BDBM691554(US20240279215, Compound 15 | 4-chlorobenzyl (4-(1-...)
Affinity DataEC50:  2.16E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691668BDBM691668(US20240279215, Compound 129 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  2.22E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691675BDBM691675(US20240279215, Compound 136 | 4-chlorobenzyl (4-((...)
Affinity DataEC50:  2.23E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691680BDBM691680(US20240279215, Compound 141 | 4-chlorobenzyl (S)-(...)
Affinity DataEC50:  2.24E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691986BDBM691986(US20240279215, Compound 447 | oxazol-5-ylmethyl (4...)
Affinity DataEC50:  2.31E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691960BDBM691960(US20240279215, Compound 421 | methyl 8-(4-(((oxazo...)
Affinity DataEC50:  2.33E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

TargetNicotinamide phosphoribosyltransferase(Human)
Cytokinetics, Incorporated

US Patent
LigandChemical structure of BindingDB Monomer ID 691898BDBM691898(US20240279215, Compound 360 | US20240279215, Compo...)
Affinity DataEC50:  2.33E+3nMAssay Description:Compounds described herein were assayed for their ability to stimulate the synthesis of nicotinamide mononucleotide (NMN) by the enzyme NAMPT. The hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
US Patent

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