Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 12393
LigandChemical structure of BindingDB Monomer ID 700285BDBM700285(Dimethyl-oxo-[[2-[[4-[4-(4-pyridyl)-1H-pyrazol-3-y...)
Affinity DataIC50: 0.0500nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700283BDBM700283(2-[[4-[4-(4-Pyridyl)-1H-pyrazol-3-yl]phenoxy]methy...)
Affinity DataIC50: 0.0630nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700280BDBM700280(N-[Dimethyl(oxo)-lambda6- sulfanylidene]-2-[[4- [1...)
Affinity DataIC50: 0.0630nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700235BDBM700235(N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[4-(...)
Affinity DataIC50: 0.0630nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700215BDBM700215(2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700249BDBM700249(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700244BDBM700244(2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700291BDBM700291(4-[2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]pheno...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700216BDBM700216(Ammonium 2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl...)
Affinity DataIC50: 0.0790nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700252BDBM700252(N-(Cyclopropyl- methyl-oxo-lambda6- sulfanylidene)...)
Affinity DataIC50: 0.100nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700284BDBM700284(N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[4-(...)
Affinity DataIC50: 0.100nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700282BDBM700282(2-[[4-[4-(4-Pyridyl)-1H-pyrazol-3-yl]phenoxy]methy...)
Affinity DataIC50: 0.100nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700248BDBM700248(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [4-[1-...)
Affinity DataIC50: 0.100nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700257BDBM700257(N-[Dimethyl(oxo)-λ6-sulfanylidene]-2-[[4-[1-m...)
Affinity DataIC50: 0.120nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700256BDBM700256(N-Methyl-2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl...)
Affinity DataIC50: 0.135nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700251BDBM700251(2-[[4-[1-Methyl-4-(4- pyridyl)pyrazol-3- yl]phenox...)
Affinity DataIC50: 0.138nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700250BDBM700250(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[4...)
Affinity DataIC50: 0.145nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700263BDBM700263(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.174nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700214BDBM700214(2-[[4-[2-Methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]...)
Affinity DataIC50: 0.204nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700288BDBM700288(1-Methyl-3-[2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3...)
Affinity DataIC50: 0.214nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700233BDBM700233(N-[Dimethyl(oxo)-λ6-sulfanylidene]-5-methyl-2...)
Affinity DataIC50: 0.224nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700290BDBM700290(4-[2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]pheno...)
Affinity DataIC50: 0.224nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700269BDBM700269(N-[Dimethyl(oxo)-lambda6- sulfanylidene]-5- fluoro...)
Affinity DataIC50: 0.257nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700287BDBM700287(N-[2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]pheno...)
Affinity DataIC50: 0.288nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700268BDBM700268(N-[Dimethyl(oxo)-lambda6- sulfanylidene]-6- fluoro...)
Affinity DataIC50: 0.324nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700292BDBM700292(1-[2-[[4-[1-Methyl-4-(4-pyridyl)pyrazol-3-yl]pheno...)
Affinity DataIC50: 0.347nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700289BDBM700289(1-[Dimethyl(oxo)-λ6-sulfanylidene]-3-[2-[[4-[...)
Affinity DataIC50: 0.347nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700294BDBM700294(1-[3-[[4-[1-Methyl-4- (4-pyridyl)pyrazol- 3- yl]ph...)
Affinity DataIC50: 0.355nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700261BDBM700261(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-2- [[4-[1...)
Affinity DataIC50: 0.372nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700213BDBM700213(2-[[4-[2-Methyl-4-(4-pyridyl)pyrazol-3-yl]phenoxy]...)
Affinity DataIC50: 0.372nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700281BDBM700281(2-[[4-[1-Cyclopropyl- 4-(4-pyridyl)pyrazol- 3- yl]...)
Affinity DataIC50: 0.380nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700278BDBM700278(N-[Dimethyl(oxo)-lambda6- sulfanylidene]-6- fluoro...)
Affinity DataIC50: 0.389nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700217BDBM700217(2-[4-(4-Pyridyl)-3-[4-(2-quinolylmethoxy)phenyl]py...)
Affinity DataIC50: 0.389nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700258BDBM700258(N-[Dimethyl(oxo)- lambda6-sulfanylidene]-3- [[4-[1...)
Affinity DataIC50: 0.457nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700286BDBM700286(Imino-methyl-oxo-[2-[[4-[4-(4-pyridyl)-1H-pyrazol-...)
Affinity DataIC50: 0.479nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700255BDBM700255(N-Methyl-2-[[4-[1-methyl-4-(4-pyridyl)pyrazol-3-yl...)
Affinity DataIC50: 0.603nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700279BDBM700279(5-Chloro-N- [Dimethyl(oxo)-lambda6- sulfanylidene]...)
Affinity DataIC50: 0.741nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700293BDBM700293(2-[[4-[1-Methyl-4-(4- pyridyl)pyrazol-3- yl]phenox...)
Affinity DataIC50: 1.05nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700295BDBM700295(2-[[4-[1-Methyl-4-(4- pyridyl)pyrazol-3- yl]phenox...)
Affinity DataIC50: 1.10nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700218BDBM700218(2-[[4-[1-Methylsulfonyl-4-(4-pyridyl)pyrazol-3-yl]...)
Affinity DataIC50: 4.37nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700264BDBM700264(N-[Dimethyl(oxo)-λ6-sulfanylidene]-7-fluoro-2...)
Affinity DataIC50: 4.79nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 700272BDBM700272(N-[Dimethyl(oxo)-lambda6- sulfanylidene]-6- methyl...)
Affinity DataIC50: 5.13nMAssay Description:Semi Log compound dilutions starting at a final concentration of 50 μM were dispensed into a black 384 well plate alongside, DMSO and an Inhibit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent