Compile Data Set for Download or QSAR
Report error Found 1004 Enz. Inhib. hit(s) with all data for entry = 12436
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702884BDBM702884(((1S,2R)-2-fluorocyclopropyl)(3-(2-(1-methyl-1H-py...)
Affinity DataIC50: 0.100nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702890BDBM702890(US20240360157, Example 244)
Affinity DataIC50: 0.200nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702885BDBM702885(US20240360157, Example 239)
Affinity DataIC50: 0.200nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702863BDBM702863(((1S,2R)-2-fluorocyclopropyl)(3-(2-(2-(methylamino...)
Affinity DataIC50: 0.400nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702891BDBM702891(US20240360157, Example 245)
Affinity DataIC50: 0.400nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702887BDBM702887(US20240360157, Example 241)
Affinity DataIC50: 0.400nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702846BDBM702846(((1S,2R)-2-fluorocyclopropyl)(3-(2-(1-methyl-1H-py...)
Affinity DataIC50: 0.400nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702745BDBM702745(US20240360157, Example 99)
Affinity DataIC50: 0.700nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702663BDBM702663(US20240360157, Example 17)
Affinity DataIC50: 1nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702883BDBM702883(cyclopropyl(3-(2-(1-(difluoromethyl)-1H-pyrazol-4-...)
Affinity DataIC50: 1.10nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702805BDBM702805(((1S,2R)-2-fluorocyclopropyl)(3-(6-(1-methyl-1H-py...)
Affinity DataIC50: 1.10nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702816BDBM702816(US20240360157, Example 170)
Affinity DataIC50: 1.20nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702780BDBM702780(US20240360157, Example 134)
Affinity DataIC50: 1.40nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702667BDBM702667(US20240360157, Example 21)
Affinity DataIC50: 1.40nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702747BDBM702747(US20240360157, Example 101)
Affinity DataIC50: 1.40nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702893BDBM702893(US20240360157, Example 247)
Affinity DataIC50: 1.40nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702664BDBM702664(US20240360157, Example 18)
Affinity DataIC50: 1.5nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702847BDBM702847(((S)-2,2-difluorocyclopropyl)(3-(2-(1-methyl-1H-py...)
Affinity DataIC50: 1.5nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702817BDBM702817(US20240360157, Example 171)
Affinity DataIC50: 1.5nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702668BDBM702668(US20240360157, Example 22)
Affinity DataIC50: 1.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702764BDBM702764(US20240360157, Example 118)
Affinity DataIC50: 1.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702815BDBM702815(US20240360157, Example 169)
Affinity DataIC50: 1.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702862BDBM702862((3-(2-(3-fluoro-1-methyl-1H-pyrazol-4-yl)-3H-imida...)
Affinity DataIC50: 1.90nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702734BDBM702734(((1S,2R)-2-fluorocyclopropyl)(3-(6-(2-methoxypyrid...)
Affinity DataIC50: 1.90nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702665BDBM702665(US20240360157, Example 19)
Affinity DataIC50: 2.10nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702819BDBM702819(US20240360157, Example 173)
Affinity DataIC50: 2.40nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702848BDBM702848(US20240360157, Example 202)
Affinity DataIC50: 2.5nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702859BDBM702859(US20240360157, Example 213)
Affinity DataIC50: 2.5nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702746BDBM702746(US20240360157, Example 100)
Affinity DataIC50: 2.5nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702762BDBM702762(US20240360157, Example 116)
Affinity DataIC50: 2.60nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702818BDBM702818(US20240360157, Example 172)
Affinity DataIC50: 2.60nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702867BDBM702867((3-(6-(1-(difluoromethyl)-1H-pyrazol-4-yl)-7H-pyrr...)
Affinity DataIC50: 2.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702889BDBM702889(US20240360157, Example 243)
Affinity DataIC50: 2.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702758BDBM702758(US20240360157, Example 112)
Affinity DataIC50: 2.90nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702774BDBM702774(US20240360157, Example 128)
Affinity DataIC50: 2.90nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702863BDBM702863(((1S,2R)-2-fluorocyclopropyl)(3-(2-(2-(methylamino...)
Affinity DataIC50: 3nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702759BDBM702759(US20240360157, Example 113)
Affinity DataIC50: 3nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702755BDBM702755(US20240360157, Example 109)
Affinity DataIC50: 3.20nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702778BDBM702778(US20240360157, Example 132)
Affinity DataIC50: 3.30nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702750BDBM702750(US20240360157, Example 104)
Affinity DataIC50: 3.40nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702757BDBM702757(US20240360157, Example 111)
Affinity DataIC50: 3.60nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702768BDBM702768(US20240360157, Example 122)
Affinity DataIC50: 3.70nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702760BDBM702760(US20240360157, Example 114)
Affinity DataIC50: 3.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702775BDBM702775(US20240360157, Example 129)
Affinity DataIC50: 3.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702882BDBM702882(cyclopropyl(3-(2-(1-methyl-1H-pyrazol-4-yl)-1H-pyr...)
Affinity DataIC50: 3.80nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702890BDBM702890(US20240360157, Example 244)
Affinity DataIC50: 4nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702898BDBM702898(((1S,2R)-2-fluorocyclopropyl)(3-(2-(1-methyl-1H-py...)
Affinity DataIC50: 4nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702886BDBM702886(US20240360157, Example 240)
Affinity DataIC50: 4.40nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702851BDBM702851(US20240360157, Example 205)
Affinity DataIC50: 4.60nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 702767BDBM702767(US20240360157, Example 121)
Affinity DataIC50: 4.70nMAssay Description:The kinase activity of recombinantly generated catalytic kinase (also known as JH1) domain of human JAK1, JAK2, JAK3 and TYK2 were evaluated in a pla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2025
Entry Details
US Patent

Displayed 1 to 50 (of 1004 total ) | Next | Last >>
Jump to: