Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 12497
Affinity DataIC50: 10.6nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HTT HEK293 cells were prepared in a 384 mic...More data for this Ligand-Target Pair
Affinity DataIC50: 21.9nMAssay Description:SERT inhibition was measured using a Neruotransmitter Transportation Fluorescence assay. Briefly, stable 5HTT HEK293 cells were prepared in a 384 mic...More data for this Ligand-Target Pair
TargetIsoform 2 of 3',5'-cyclic-AMP phosphodiesterase 4D(Homo sapiens (Human))
Sensorium Therapeutics
US Patent
Sensorium Therapeutics
US Patent
Affinity DataIC50: 2.70E+3nMAssay Description:Step 1:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution.2) Add 25 μl of FAM-Cyclic-3′,5′-AMP (200 nM) t...More data for this Ligand-Target Pair
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)(Human)
Sensorium Therapeutics
US Patent
Sensorium Therapeutics
US Patent
Affinity DataIC50: 3.20E+3nMAssay Description:Step 1:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution.2) Add 25 μl of FAM-Cyclic-3′,5′-AMP (200 nM) t...More data for this Ligand-Target Pair
TargetIsoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4A (RD1)(Human)
Sensorium Therapeutics
US Patent
Sensorium Therapeutics
US Patent
Affinity DataIC50: 4.30E+3nMAssay Description:Step 1:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution.2) Add 25 μl of FAM-Cyclic-3′,5′-AMP (200 nM) t...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+4nMAssay Description:Step 1:1) Dilute 20 μM FAM-Cyclic-3′, 5′-AMP stock 100-fold with PDE buffer to make a 200 nM solution.2) Add 25 μl of FAM-Cyclic-3′,5′-AMP (200 nM) t...More data for this Ligand-Target Pair
