Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 12604
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Cardurion Pharmaceuticals

US Patent
LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 10nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Cardurion Pharmaceuticals

US Patent
LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 10nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Cardurion Pharmaceuticals

US Patent
LigandPNGBDBM712953(US20250019381, Compound (P2))
Affinity DataIC50: 36nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Cardurion Pharmaceuticals

US Patent
LigandPNGBDBM559569(US11608342, Compound (P1) | US11370795, Compound (...)
Affinity DataIC50: 42nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Cardurion Pharmaceuticals

US Patent
LigandPNGBDBM50397838(CHEMBL2179105 | US10513524, Reference compound dis...)
Affinity DataIC50: 70nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandPNGBDBM247206(US9434733, 2-[[3-[(4-fluorophenyl)methoxy]azetidin...)
Affinity DataIC50: 1.01E+3nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

LigandPNGBDBM50397838(CHEMBL2179105 | US10513524, Reference compound dis...)
Affinity DataIC50: 2.50E+3nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

LigandPNGBDBM426313(US10513524, Compound (P3 | US11608342, Compound (P...)
Affinity DataIC50: 3.00E+3nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

LigandPNGBDBM712953(US20250019381, Compound (P2))
Affinity DataIC50: 5.28E+3nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent

LigandPNGBDBM559569(US11608342, Compound (P1) | US11370795, Compound (...)
Affinity DataIC50: 4.51E+4nMAssay Description:Non-limiting examples of PDE9 inhibitors of formula (II) are disclosed in WO 2013/110768, the contents of which are incorporated herein by reference ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2025
Entry Details
US Patent