Compile Data Set for Download or QSAR
Report error Found 116 Enz. Inhib. hit(s) with all data for entry = 12755
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725642BDBM725642(US20250074895, Compound 23)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725641BDBM725641(US20250074895, Compound 22)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725640BDBM725640(US20250074895, Compound 21)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725639BDBM725639(US20250074895, Compound 20)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725646BDBM725646(US20250074895, Compound 27)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725645BDBM725645(US20250074895, Compound 26)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725644BDBM725644(US20250074895, Compound 25)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725643BDBM725643(US20250074895, Compound 24)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725634BDBM725634(US20250074895, Compound 15)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725633BDBM725633(US20250074895, Compound 14)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725631BDBM725631(US20250074895, Compound 12)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725638BDBM725638(US20250074895, Compound 19)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725636BDBM725636(US20250074895, Compound 17)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725635BDBM725635(US20250074895, Compound 16)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725658BDBM725658(US20250074895, Compound 39)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725656BDBM725656(US20250074895, Compound 37)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725655BDBM725655(US20250074895, Compound 36)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725662BDBM725662(US20250074895, Compound 43)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725660BDBM725660(US20250074895, Compound 41)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725650BDBM725650(US20250074895, Compound 31)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725649BDBM725649(US20250074895, Compound 30)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725648BDBM725648(US20250074895, Compound 29)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725647BDBM725647(US20250074895, Compound 28)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725654BDBM725654(US20250074895, Compound 35)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725653BDBM725653(US20250074895, Compound 34)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725652BDBM725652(US20250074895, Compound 33)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725651BDBM725651(US20250074895, Compound 32)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725674BDBM725674(US20250074895, Compound 55)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725673BDBM725673(US20250074895, Compound 54)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725672BDBM725672(US20250074895, Compound 53)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725671BDBM725671(US20250074895, Compound 52)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725677BDBM725677(US20250074895, Compound 58)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725676BDBM725676(US20250074895, Compound 57)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725675BDBM725675(US20250074895, Compound 56)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725666BDBM725666(US20250074895, Compound 47)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725665BDBM725665(US20250074895, Compound 46)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725664BDBM725664(US20250074895, Compound 45)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725663BDBM725663(US20250074895, Compound 44)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725670BDBM725670(US20250074895, Compound 51)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725669BDBM725669(US20250074895, Compound 50)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725668BDBM725668(US20250074895, Compound 49)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725667BDBM725667(US20250074895, Compound 48)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725626BDBM725626(US20250074895, Compound 7)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725625BDBM725625(US20250074895, Compound 6)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725624BDBM725624(US20250074895, Compound 5)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725623BDBM725623(US20250074895, Compound 4)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725630BDBM725630(US20250074895, Compound 11)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725629BDBM725629(US20250074895, Compound 10)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725628BDBM725628(US20250074895, Compound 9)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Blueprint Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 725627BDBM725627(US20250074895, Compound 8)
Affinity DataIC50: 10nMAssay Description:nhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the enzymatic phosphorylation activity of CDK e...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
7/9/2025
Entry Details
US Patent

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