Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 13257
TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771611(US20250084112, Example 3A)
Affinity DataIC50: 10nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771601(US20250084112, Example 1A)
Affinity DataIC50: 10nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771605(US20250084112, Example 2A)
Affinity DataIC50: 20nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771613(US20250084112, Example 4A)
Affinity DataIC50: 31.6nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771606(US20250084112, Example 3)
Affinity DataIC50: 126nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771600(US20250084112, Example 1)
Affinity DataIC50: 158nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771603(US20250084112, Example 2)
Affinity DataIC50: 251nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent

TargetSodium channel protein type 10 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM771612(US20250084112, Example 4)
Affinity DataIC50: 794nMAssay Description:Human embryonic kidney 293 cells (HEK293) expressing human Nav1.8, human Navβ1 and human TREK1 (HEK293-Nav1.8) were grown at 37° C., 5% CO2 in 150 cm...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
12/30/2025
Entry Details
US Patent